From the monthly archives:

October 2009

Recently I saw a patient who had been diagnosed in 1983 with a malignant tumor in her right breast. For reasons of her own, she had refused any form of conventional treatment, including radiation, chemotherapy, and hormones. She told me that the tumor was quite large but had not spread to any lymph nodes under her arm. “I think I’d better examine it,” I said, and she hesitated.

“I should warn you,” she said, “that most doctors are very frightened when they see this, because of its size. I generally don’t even let a doctor touch me, because the fear in their eyes makes me scared. On my own I’m not scared. You may not believe this, but I have never felt that I was in any danger. I can be shaken, though, when I see a doctor’s fear. They even say things like, ‘How dace you be so cruel to your husband by not having
surgery:

“I thought that maybe a woman doctor would be more understanding, but w.hen 1 went to one, she was more horrified than the rest. She asked me.
Why did you come to see me if you arent going to me
remove that thing?’ And I said, ‘Because I just want you to monitor it has grown slightly in the past five years, and I want it followed. Almost shaking she stood up and told me, ‘Don’t come back to see me unless you want that thing removed. I can’t stand the sight of it.”

I had no idea what my react ion would be. About half of the women diagnosed with breast cancer have localized tumors confined to the breast. The standard treatment has been either to remove the breast or to remove the lump and radiate the site to kill any remaining cancer cells. In both cases, when there is no further follow-up treatment, 70 percent of patients do not have a recurrence in the next three years. With some sort of chemotherapy, ranging
mild to quite heavy, the proportion of long-term survivors can be raised to 90 percent. This woman had decided to defy odds that were very much in the patient’s favor and yet she would not be the first to ignore doctors and survive.

When she lay on the examining table and I saw the tumor, I understood why her previous doctors had been shocked it distended a large portion of her breast. I controlled my automatic reaction, and I hope no fear showed in my eyes. I sat down and held her hand, thinking. “Look,” I said softly, “I don’t believe you are in danger here. You have said that you don’t feel any danger, and that is good enough for me. But this rumor is a nuisance. You are denying yourself a more beautiful life by having to look after this. Why not go to a surgeon and have the nuisance removed?”

Apparently this struck her as an entirely new angle. She readily agreed that there was no advantage to keeping the tumor, and
referred her to a sympathetic surgeon. One of her parting comments stays with me. “I don’t identify myself with this tumor,” she said serenely, “I know I am much more than it. It will come and go like the rest of me, but inside, I am not really touched by it.” When she left the office, she looked extremely happy. I felt that this woman had reason on her side. The fear in a doctor’s eyes is a terrible stroke of condemnation, and in her position I would not have believed much in my chances of recovery. The impulses from my brain would not be saying, ”I’m definitely going to recover.” Instead, they would be saying, “They tell me I’ll probably recover,” which is quite a different thing,

When a doctor looks at a patient and says, “You have breast cancer, but you’re going to get well,” what is he really saying? The answer is by no means certain. At one extreme, his reassuring words, if they are believable, may be enough to make the difference in the patient’s case, At the other extreme, if he actually thinks the patient is doomed, some· thing in his voice will give that message, and from it a destructive confusion may set in.

Recently the term placebo was inverted into a new term, nocebo, to describe the negative effects of a doctor’s opinion. With placebo, you give a dummy drug and the patient responds because the doctor has told him that the drug ‘will work. With nocebo, you give a viable drug, but the patient doesn’t respond , because the doctor has signaled that the drug isn’t going to work,

If you take a completely materialistic view, there seems no difference between the surgery this woman refused before and the one she agreed to now. Yet, now she identifies surgery .with healing, whereas before it was violence, If a patient regards any treatment as violence, then his body will be flooded with negative emotions and the chemicals associated with them, It is well documented that ill a climate of negativity, the ability to heal is greatly reduced depressed people not only lower their immune response, fur example, but even weaken their DNA’s ability to repair itself. So my patient had reasonable cause, I think, to wait until her emotions told her to go ahead,

This case reminds me ·that there are always two centers of action within people, the head and the heart, Medical statistics appeal to the head, but the heart keep its own counsel. In recent years, alternative medicine has won much of its appeal on the ‘ basis of bringing back the heart, using love and airing to heal. Without these ingredients, nocebo effect can run would for the surroundings of
modem hospitals inject a powerful dose of it. The psychotic episodes that sometimes strike our of the blue in intensive care units show how unhealthy it is to hold people in sterile, confined spaces. (As a young child, my son showed an almost equal. fascination with hospitals and prisons, which I trace to a fear he could not express. If the saw either institution from the car, he would invariably ask, “Daddy, are people dying in there?”)

The great drawback of proclaiming that we need to bring the heart back into medicine is that it punishes people for their emotional weak lessees. The heart can be very frail; it can be hardened by suffering, or just by life. articels on holistic healing like to say that sick people “need” their sickness. Mainstream psychiatry points its own finger when it says that chthonic diseases can stand symbolically for self-punishment, revenge, or a deep feeling of worthlessness. I will not argue these insights, except to suggest that they may be harmful to the healing process rather than helpful. It is hard enough for any of us to face up to our emotional fallibility even at the best of times. Can we really be expected to reform when we are ill?

The deeper issue is that anything can function as a nocebo, just as anything can function as a placebo. It is not the dummy drug, the doctor’s bedside manner, or the antiseptic smell of a hospital that does harm or good; it is the patient’s interpretation of it. Therefore, the real war is not between the head and the heart. Something deeper, in the realm of silence, creates our view of reality.

The basic understanding most, of us have about ourselves comes from thinking and feeling, which seems only natural. But we know very little about the field of silence and how it exercises control over us. The head and the heart, it seems, are not the whole person. The stream of consciousness, which is constantly full of thoughts, acts as a screen to help silence hidden. The solid appearance of the physical body is another kind of screen, since we cannot see the molecules that are being constantly shuffled around ‘inside us, much less their blueprint, which is what we would like to change.

The blueprint of reality is an important concept. Every impulse of intelligence gives rise to a thought or a molecule, which spends a certain time in the relative world the world of the Senses before the next impulse follows. In that sense, every thought is like a piece of the future when it is created, a piece of the present when if is experienced, and a piece of the past after it has gone. As long as each impulse is healthy, the future is nor unknown it will Bow naturally from the present, moment by moment. (This accounts for why people who make the most of every day tend to retain their mental faculties intact into old age; the stream of intelligence is never allowed to dry up.)

Above the line is a flow of thoughts that never· ends, at· least while we are awake. Thought is linked to thought without end. Our normal experience keeps within this range of ongoing events, which may be infinite
on the horizontal axis yet quite shallow on ·the vertical. It is possible to spend a lifetime listening to the inventory of the mind without ever dipping into its source. Yet, touching the source is how the mind creates its patterns of intelligence’. These patterns are at first only blueprints, but whatever they inscribe will hold they will form our ideas and beliefs about reality.

The field of intelligence is extremely sensitive to change, however, both for good and ill. Two years ago I saw a woman in her thirties who came to Lancaster to be treated for breast cancer. Her condition was extremely serious, since the malignancy had metastasized to the bone marrow everywhere in her body. She suffered from constant pain in her hones as a result. After receiving the normal, and quite drastic, courses of radiation and chemotherapy from her doctor at home in Denver, she came to Boston for Ayurvedic treatments. She responded very well. After spending a week as an inpatient, her bone pain disappeared. She was not offered any promises about her cancer, ‘but she went home in a state of renewed hope and optimism. Unfortunately, when she reported to her doctor that she had improved, he told her that it was all in her head she had received no orthodox therapy that could have relieved her symptoms. Within a day her bone pain returned. She called me, feeling panicky, and I asked if she could return to Boston immediately. She did, and fortunately after another week het bone pain again receded.

Without intending to harm his patient I am sure he wanted to be realistic in his appraisal this woman’s doctor made a Cruel mistake. He assumed that what is “in your head” is nor real, or at least very inferior to the reality of cancer. Being trained in scientific methods, he knew the predictable outcomes of various kinds of malignancy, and when he saw an unexpected result, he tried to push it back into the range of the predictable. Doctors push patients into predictable results all the time, because medical-school training is focused entirely on the horizontal axis.

Making the links of cause and effect tighter and tighter is the whole motivation behind medical research. Our great-grandfathers vaguely knew that germs existed; we can anatomize thousands of specific viruses and bacteria, down to the tiniest amino-acid groups and beyond. Unfortunately, this leaves very little opening for any journey along the vertical
axis, which might take one to a deeper reality.

A recent patient listed on his medical questionnaire that he “once had a brain tumor.” I asked him what that meant, and he told me this story: About five years ago, while living in Michigan, he began to have sudden dizzy spells. These quickly grew worse, and in a few weeks he was vomiting and had double vision, with increasing loss of balance and motor coordination. He went to a hospital, where a CAT scan was taken of his brain. The doctors informed him that the test had disclosed a shadowy mass in his forebrain larger than a lemon; in their opinion, he had a brain tumor. A tissue sample taken from the rumor revealed that indeed it was a deadly, rapidly growing cancer.

Because the tumor was so large and delicately placed, it was considered inoperable. The doctors recommended high doses of radiation and chemotherapy, without which the man would be dead in six months. The therapy would have severe side effects, nearly as bad as his present symptoms. Certain of these, such as nausea, headaches, and skin irritation, would be ‘ uncomfortable; others, such ‘as the weakening of his immune system, could be deadly, since he would become prone to contracting other types of cancer in the future. There was also the definite possibility that he would be prey to anxiety and depression, which could be lasting. Even with maximum treatment to shrink the tumor, the prognosis for full recovery was not good, bur it was better than nothing.

The patient could not accept this reasoning (although it is statistically quite sound). He moved to California and joined a meditation group; he practiced a whole series of diets, mental techniques, exercises, and visualizations. He encouraged in himself a totally positive attitude toward his condition. Thousands of cancer parents, as a rule from the best-educated groups, rum to such measures, which conventional medicine looks on as trying to buy false hope. In this case, however, the man began to feel better, and within six months his symptoms were almost completely gone’. Hopeful but also anxious, he returned to Michigan and underwent another CAT Scan. This one showed no traces of cancer and no sign that any had ever been present.

In response to this, his doctors informed him that he had not recovered from cancer, because they had never heard of such a recovery. In fact, they said, the original CAT scan was not his but another patient’s. They were sorry for the mistake, but from that moment on, they disavowed any involvement with his case, The patient was immensely relieved that his symptoms were gone, and he believes in the original CAT, scan, which has his name and Social Security number On it. When I contacted the hospital to ask for-his records, I was informed that he had never been treated there for cancer bur had been mixed up with another brain-tumor patent.

All I can assume is that even with X rays and a biopsy, these doctors could not accept that a remission had occurred, for the simple reason that their experience told them it was impossible. One should never underestimate the power of indoctrination. Medical training is highly technical, specialized, and rigorous, bur it came about just like any other, human activity by people collecting experiences and using those experiences to form explanations and patterns. These patterns in turn serve to indoctrinate the pattern makers, and within a very short period of rime the indoctrination becomes law,

It is fascinating that a major study of four hundred spontaneous remissions of cancer, later interpreted by Elmer and Alyce Green of the Menninger Clinic, found that all the partiers had only one thing in common every person had changed his attitudes before the remission occurred, finding some way to become hopeful, courageous, and positive, In other words, they broke down their indoctrination (eve!! if the doctors did not break down theirs), The mystery that clouds this otherwise clear finding has to do with causation. Did the remissions occur because of the new attitudes or parallel to them? Perhaps causation is too delicate to pinpoint in this case, being replaced by a general, holistic process of getting well in mind and body at the same .time. The mind-body system, about to throw off the cancer, should know that the process is under way and may begin to generate much more positive thoughts simultaneously.

However it works, the key seems to be spontaneity. Channeling positive attitudes into oneself as a planned therapy has proved only haphazardly successful as a means of fighting disease. The positive input does not tend to go very deep. Consciousness is more pervasive than medicine gives it credit for. Even when it is ignored, however, the silent field of intelligence knows what is happening. It is, after all, intelligent. Its knowledge reaches’ beyond buffers and screens, going farther than we expect.

To illustrate: for decades, surgeons safely assumed that an anesthetized patient was unconscious and therefore not influenced by what happened in the operating room. Then it was discovered (by hypnotizing postoperative patients) that in fact the “unconscious” mind heard every word that was uttered during the procedure. When the surgeons said aloud that a condition was more serious than they had thought or had little chance of cure, the patients tended to play out those gloomy predictions by not recovering. As a result of these finding, which validate the ides of nocebo, it is now standard practice not to make negative remarks during surgery. The more positive the surgeon’s expressed opinions, in fact, the more positive the outcome for the patient.

It would be even better to use this highly sensitive, extremely powerful intelligence for the patient’s cure. The point of diving into the region of the quantum body is to change the blueprint itself, rather than to wait for symptoms on the surface, which will then have to be manipulated using medicine. The case of the woman with bone pain is a reminder that the buffer that keeps us so securely above the line, away revision at any time. We constantly build patterns of intelligence and look through them to tell us what is real. If we see pain, there is pain, but if we don’t the pain will be gone.

Nature did not make us ignorant of our deeper selves. Anesthetized patients have known what was going on all along, presumably since the beginnings of modern surgery in the 1850s. The silent field of intelligence is out of reach by our choice, reinforced through generations of cultural bias. Sometimes a new reality forces itself to be recognized, and then things can shift. New patterns of intelligence arise; a deep transformation can then take place, but it is not essentially different from the mind-body transformations we have already been talking about.

Normal reality is like a spell a very necessary one, since we must live by habits, routines, and codes that we take for granted. The problem arises when you can make the spell but not break it. If you could dive, this very minute, below your everyday reality to its source, you would certainly have a remarkable experience. The psychologist Abraham Maslow, who was a pioneer in studying the positive aspects of the human personality, gave a classic description of the experience of the deep self: “These moments were of pure, positive happiness, when left behind. Now self-consciousness was lost. All separateness and distance from the world disappeared.”

Although such experiences are rare Maslow termed them “peak experiences” for that reason they have a curative power that goes far beyond their brief durations, which may be a few days or just a few hours. Maslow records that two of his patients, one a long-term depressive who had often considered suicide, the other a person who suffered from severe anxiety attacks, were both immediately and permanently cured after spontaneously falling into such experiences (for each it happened only once)

Maslow also talks about the reconciliation with life that people have realized through these moments: “They felt one with the world, fused with it, really belonging to it instead of being outside looking in. (One subject said, for instance, ‘I felt like a member of a family, not like an orphan.’)

Any sudden revelation of a deeper reality carries enormous power with it one taste alone can make life undeniably worthwhile. Maslow’s patients recognized this inner power as something quite outside the ordinary. It is not energy or strength, genius or insight, but it underlies all of these. It is life power in its purest from. Maslow’s understanding stopped short at the critical moment he was never able actually to give anyone a peak experience yet he was fascinated by these events that transcend normal life. In 1961, after several decades of writing and thinking about the subject, he concluded that it was indeed normal life and not the mystical that he had been observing:

“The little that I had ever read about mystic experiences tied them in with religion, with visions of the supernatural. And, like most scientists, I had sniffed at them in disbelief and considered it all nonsense, maybe hallucinations, maybe hysteria almost surely pathological. But the people telling me about these experiences were not such people they were the healthiest people.”

Because he detected these experiences in fewer than I percent of the population, Maslow viewed them as accidents or as moments of grace. I believe that they were glimpses into a field that underlies everyone’s life but which has remained elusive. The implication is that we should dive very deep if we want to transcend normal reality. We are in search of an experience that will reshape the world.

Finding the silent gap that flashes in between our thoughts seems relatively easy, but because it flashes by, a tiny gap is not a doorway. The quantum body is not separate from us it is us yet we are not experiencing it right now. Sitting her, we are thinking, reading, talking, breathing, digesting, and so on, all of which happens above the line.

Here is an analogy that brings the quantum mechanical body into focus: Take a bar magnet and place a piece of paper over it. Next, sprinkle iron filings on the paper and jostle it slightly. What will emerge is a pattern of curving lines, one inside the other, that arch form the magnet’s north to south pole and back again. The overall design you have made represents a map of the magnetic lines of force that otherwise would be invisible, except that the iron particles automatically align themselves to bring out the image.

In this analogy, we see all mind-body activity above the paper and the hidden field of intelligence below. The iron filings moving around are mind-body activity, automatically aligning with the magnetic field, which is intelligence. The field is completely invisible and unknowable until it shows its hand by moving some bits of matter around. And the piece of paper? It is the quantum mechanical body, a thin screen that shows exactly what patterns of intelligence are being manifested at the moment.

There is more to this simple comparison than you might at first suppose. Without the paper to separate the two, the magnet and the iron cold not interact in any orderly way. Try bringing a magnet close to some iron filings. Instead of forming regularly spaced lines, the filings simply clump shapelessly onto the magnet’s surface. With the paper in place, not only do you can watch the iron filings move to mirror the new field that has been created. If you didn’t know that there was a magnet, you would sweat that the iron was alive, because it seems to move by itself. But it is really the hidden field that is generating these lifelike appearances.

There you have a true picture of how the body-mind actually relates to the field of intelligence. The tow remain separated, but the division is invisible and has no thickness whatever. It is just a gap. The only way one knows that the quantum level even exists is that images and patterns keep cropping up everywhere up everywhere in the body. Mysterious furrows run across the surface of the brain; beautiful swirls, exactly like the center of a sunflower, show up in molecules of DNA; the inside of the femur contains marvelous webs of bone tissue, like the intricate supports of a cantilever bridge.

Wherever you look, there is no chaos, and that is the strongest proof of all that there really is a hidden physiology. Intelligence turns chaos into patterns. There is incredible chaos implied in the idea of having to process billions of chemical messages every minute, yet in reality, the complexity of the mind-body system is misleading: what emerges from our brains are coherent images, just as a coherent newspaper photograph emerges from thousands of scattered dots. The matter in our bodies never disintegrates into a shapeless, mindless pile until the moment of death. In answer to the obvious question, “Where is this quantum mechanical body, anyway?” one can now confidently answer that it lies in a gap that unfortunately is rather difficult to picture, since it is silent, has no thickness, and exists everywhere.

To dive into the field of intelligence appears easy now: it requires only trip across a gap. But even though the gap has no thickness, it forms a barrier no steel door could possibly match. We can simplify our diagram to show what has happened to make the journey so difficult:

The whole story is contained in the difference between active and silent intelligence. We have confirmed that this difference is very real. DNA can be active or silent; our thoughts can be expressed or stored away in drawers of silence; we can be awake or asleep. All these changes require a journey across the gap, but not a conscious journey. To see what sleep is like, you would have to stay awake, which is impossible. If you want to see the difference between active and dormant DNAs are physically identical. And so on and on for all the transformations of mind and body.

The same difficulty holds true in physics a photon is a form of light, as is a light wave, but both arise from a hidden field. On the surface of reality we see either photons or light waves, but the reason why both can exist in one reality is that they preexist as mere possibilities in the quantum field. Who has ever photographed a possibility? Yet, that is all the quantum world is made of. If you say a word or make a molecule, you have chosen to act. A little wave laps up from the ocean’s surface, becoming an incident in the space-time world. The whole ocean remains behind, a vast, silent reservoir of possibilities, of waves that have yet to be born.

As they dance around on the paper, the iron filings might look at one another and say, “Well, this is life, let’s look into its mysteries.” Deciding to do that, they can begin a thought adventure of the kind we call science. No matter how adventurous their thoughts become, they will never cross the gap. The gap is a one-way door, as far as thinking goes, and that is its true mystery.

From a certain perspective, the whole idea that we are outcroppings from an invisible, infinite field seems ridiculous. A man’s body is a packet of flesh and bones occupying a few cubic feet of space; his mind is an amazingly intricate but finite mechanism filled with a set number of conceptions; his society is a grossly imperfect organization bound to a history of ignorance and conflict.

These obvious facts have never settled the issue, strangely enough. We trust our finite everyday experiences, which are good enough for driving a car, earning a living, and going to the beach, but they are not quite convincing enough compared to the overwhelming experience of the infinite. That experience, repeated throughout the centuries, causes some people to suspect that reality is very different, and far vaster, than what the mind, the body, and society generally accept.

Einstein himself experienced this reality. He has testified to moments when “one feels free from one’s own identification which human limitation.”

“At such moments one imagines that one stands on some spot of a small planet gazing in amazement at the cold and yet profoundly moving beauty of the eternal, the unfathomable. Life and death flow into one, and there is neither evolution not destiny, only Being.”

Although this sounds like a spiritual insight (and Einstein considered himself deeply spiritual), it is really a glimpse into a level of our own consciousness that can be mapped and explored. Without having any control over their awareness or any cogent explanation for what is happening, people sense that the state of rapt silence is not simply emptiness. The great traditions of wisdom have largely been founded by one or a few individuals who realized the universe through themselves. To solve the mystery of the gap, we need to consult the ones who have been there; if they have found a real world, then there will be new Einsteins to follow, and they will be Einsteins of consciousness.

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Silent Witness

October 28, 2009

in Uncategorized

The pressing need for a quantum medicine is well illustrated, I think, by the following case study. A young Israeli named Aaron, 24 years old, called me at my office and said, “I feel perfectly healthy, but my doctor has given me ninety days to live. He took some tests which showed that I have an incurable blood disorder that as exactly twenty-three days ago.”

Barely managing to suppress his emotions, he told me a story that had taken several strange turns. His diagnosis had come about entirely··by accident. Because of an old soccer injury, he had a deviated septum, with made it difficult for him to breathe. He visited a surgeon in Chicago who could repair his nose Aaron had moved to the United Start
several years earlier to attend business school and the surgeon asked him to have a routine blood test.

When the results carne back from he lab, the doctor was very disturbed. They showed that Aaron was severely anemic: his hemoglobin count had fallen from a normal of 14 to 6 (account of 12 would be considered borderline anemic); hemoglobin is the chemical component of the blood that carries oxygen throughout the body. His hematocrit had plummeted to 16; this means that when his blood was spun in a centrifuge to separate the red. blood cells from the plasma, the red cells occupied only 16 percent of the total volume. In normal blood, this should be closer to 40 percent. Aaron was immediately referred to a blood specialist, a hematologist, who asked him a standard series of questions.

“Have you been feeling short of breath lately?

‘”No, “Aaron answered.

“Do you wake up in the middle of the night feeling suffocated?

‘”N o.

‘”Have your ankles been swelling up?”

‘”No”

The hematologist looked at him very hard. ‘”Look,” he said, ‘”you’re pretty tired all the time, aren’t you?’” Aaron shook his head. ‘”That’s amazing!” the doctor exclaimed. ‘”With your hemoglobin counts, you should be in congestive heart failure by now.’” Aaron was shocked. Looking at the blood tests, however, his doctor had a right to be amazed. In severe anemia, the heart has to work much harder than normal to supply enough oxygen to the rest of the body. This, combined with its own oxygen deprivation, causes the heart muscle to .swell, leading to congestive heart failure. The patient begins to wake up at night feeling that he is suffocating to death, and eventually that is what happens.

Mystified, the hematologist took it sample of Aaron’s bone marrow The body typically contains only 9 ounces of bone marrow, but that it enough to manufacture our total supply of red blood corpuscles, at a rate of 200 billion new cells per day. Under examination, Aaron’s marrow showed no signs of the red-cell precursors that should have been present. The hematologist now knew that ar.t1it root of Aaron’s condition was a shutdown of the bone marrow (called a plastic anemia), but he could not determine any cause for it. Even without symptoms, Aaron was very sick. “No one knows for sure how long a red blood cell lives,” the doctor said. “The accepted figure is one hundred twenty days, but it could be as short as a month. Since you are not replacing your current red cells, I’m afraid you cannot live much longer than ninety days.”

As Aaron listened numbly, the doctor told him that medicine could do very little for him the suggested treatment was a bone marrow transplant, a major operation that he might not survive and that probably would nor save him. He could be given a blood transfusion to raise his red-cell count, but the sudden incursion of another person’s blood would further dampen his bone marrow function; moreover, when the marrow detected/that the blood count was up again, it might interpret that as a sign to roll back even further.

Because he felt no symptoms, Aaron hesitated to undergo the transplant. The hematologist gave him two weeks to decide. He also said that it was his legal duty to advise the young man to settle his affairs as quickly as possible. (Aaron was not exactly treated with compassion at any step of the way. At one point, he divulged to his doctor that his older sister had died suddenly and tragically in law school. The cause of death, though vague, was thought to be a rare blood disorder, perhaps inherited. On hearing this, the hematologist enthusiastically asked Aaron to try to find out precisely what his sister had died of, since together he and she would make an excellent article for the journals. When Aaron later recounted this incident, I found myself growing extremely angry.)

Within a day of his diagnosis, Aaron began to feel short of breath and found himself unable to sleep. He sought in desperation for a way to cure himself. Almost by chance he took up meditation and heard about our Ayurvedic clinic. Within a month, he had become my patient in Lancaster. “The most hopeful thing,” I said, “is that you felt healthy before you found out what was wrong with you. Let’s go on the assumption that you are controlling this disorder and do everything we can to allow your body to heal itself.”

Without knowing what caused his disease, I found as I was interviewing Aaron that there were many points of concern. The first was the frightening diagnosis itself, which had thrown him into a panic. In such a condition, it is difficult to see how the body-mind could begin to find a route toward healing. In addition, Aaron seemed a tense and driven person. He had worked four jobs at a time while he was in school, pushing himself to the limit in order to buy a car and keep ahead of school debts. The pressure of school itself was enormous. He routinely took huge doses of vitamins, plus an anti-ulcer medication to soothe his chronic stomach pain. A few months earlier he’d had tendonitis from playing tennis too hard and had taken an anti-inflammatory agent to bring down the swelling such drugs are known to suppress bone marrow function. I asked him to discontinue all medication.

He stayed two weeks at the clinic and for the first time lived in an environment free of “normal” stress. He continued to meditate, ate a simple vegetarian diet suited to his particular body type, and received a course of massage treatments that Ayurveda prescribes to purify the physiology. I also instructed· him in the primordial sound technique suitable for his condition. One night a nurse caught him walking down the hall with wet hair, and he sheepishly confessed that he had sneaked off the property to go swimming. When I heard. this, I was very happy’ another patient with Aaron’s blood count could easily have been on oxygen and blood transfusions. The signs were more than encouraging.

On the day he left, I asked Aaron not to have any more blood tests for at least two weeks. A blood sample drawn at Lancaster had disclosed that his supply of immature red blood cells, called reticulocytes, was four times higher than when he. entered. Since these are the cells that later mature into red corpuscles, I felt that his condition had turned around. As I write, Aaron has just outlived his original prognosis. He is still severely anemic, but oil the other hand he has nor gone into .the serious decline expected of someone whose blood count “is heading toward zero. In fact, his anemia has slightly improved.

In my mind, Aaron stands on the dividing line between two kinds of medicine. The first is standard scientific medicine, whose methods are deeply ingrained in me, bur which I can no longer trust absolutely. It is not that standard medicine has failed. Aaron’s doctors expertly tracked down his disease at every level of the body, from tissues co cells co molecules in Aaron’s case, the tissue was bone marrow, the cells were red blood corpuscles, and the molecule was hemoglobin. To a doctor trained in conventional medicine, this is the end of the route, a route that has taken two centuries of painstakingly rational investigation co find. Once you know what is wrong with a person’s very molecules, what else can be known?

This logic is impeccable science, but it is dangerously divorced from the ordinary input of life. By “ordinary input” I mean what a person eats and how he sleeps, the thoughts that go through his head, and all the sights, smells, sounds, and textures that enter through his senses. You can say that the body is made out of molecules, but with equal justice you could say that it is made out of experiences. That definition matches our own self-image, which is not scientific but fluid, ‘changeable, and alive. Out of ordinary experiences, the second medicine, which is quantum, takes its origin.

We might casually think that everyday life is too commonplace and simple for science to bother with. In truth, it is fur too complex. Although a molecule of hemoglobin is structured out of 10,000 separate atoms, it can be isolated and mapped a feat that has led to several Nobel prizes. However, to trace what hemoglobin is doing when you take in a single breath would be impossible, because each red blood cell contains 280 million molecules of hemoglobin, each of which picks up 8 atoms of oxygen. Considering that the lungs expose about one quart of blood to the air per breath containing 5 trillion red cells, the total
number of chemical exchanges is astronomical. The whole process quickly Disintegrates into a swirling chaos of activity.

When you open the human body during surgery, what confronts you is not the well-defined map of textarticle anatomy, with the nerves in blue, blood vessels in red, and a green liver ready set apart from a yellow gallbladder. Instead, an uneducated eye sees a jumble of tissue that is mostly undifferentiated almost all of it is pink and moist; one organ slides imperceptibly into another. The great wonder is that scientific medicine has learned as much as it has about this pulsating chaos. But in return for its knowledge, science has paid a high price by having to abandon ordinary experience. A breath of air, after all, is not chaos, except to a molecular biologist. Breathing is the basic rhythm of life, upon which all other rhythms are based.

Eric Cassell, a professor of physiology at Cornell, astutely points out that when a doctor asks his patient questions, he is not trying to find out what is wrong with him; he is trying to find our what symptoms he might have that match a known, classified disease. This is a subtle but very important distinction. It reminds us that the whole system of organs, tissues, and so on was set up intellectually to make the body easier to classify. There muse be other views that are truer to nature, in that they rely on ordinary experience, defying nature’s disorderly exterior in order to understand its real meaning.

Chaos is just an appearance, a mask, and with a different eye it metamorphoses into pure order. Until its code was cracked, a honeybee’s dance looked like chaos, a random display of twitches and rums. Now we see it as a precise set of directions leading the other bees in the hive to a source of nectar. This does not mean that the dance changed from chaos to order, only that its appearance changed in our eyes. Similarly, if you take a few blood pressure readings from a heart patient, it is nn1ikely that they will form any pattern, but if you monitor him constantly,
definite wave pattern emerges, with peaks and valleys that occur over the space of one or two days. This fact, which was only recently uncovered, has allowed cardiologists to detect hypertension in patients who haw deceptively normal pressure in a doctor’s office because their peaks occur only at night. Clearly some kind of tidal swing is at work, bur no one yet knows its significance. The ask of chaos is too freshly broken.

The two medicines do not have’ to be antagonists, but for the moment they clearly face in opposite directions. To a hematologist, it is largely irrelevant if Aaron is tense, driven, full of dubious substances, and panicked at the thought of dying. To an Ayurvedic doctor, these are primary inputs to his sickness-they have entered oil the quantum level, where he turns into the person he is. The hematologist is not being heartless; he may care very deeply about Aaron, bur he cannot prove a connection between bone marrow dysfunction and working four jobs at a time. That is the limit where the Newtonian notion of cause and effect, the basis of standard scientific medicine, breaks down.

You cannot possibly ask enough questions to ‘ find out what really makes a patient sick. In Aaron’s case, I would want to know how he felt about his sister’s death, what he ears for bteaId3st, who his friends are, how he feels when he loses at tennis in effect, I want to know every relevant experience. This is virtually impossible. So many influences press in on us every day that the idea of causation disappears. I would think it absurd to dissect a poet’s brain to find the cause of his sonnets; his cortex undeniably had to exhibit specific brain-wave patterns to produce a sonnet, but they have evaporated and been carried to a realm hidden by time. It begins to seem just as absurd to claim that an isolated physical cause lies behind Aaron’s bone marrow dysfunction. His life is swept along by time, too, and what I want to find has evaporated.

I know this sounds shocking, because without a .cause, how can we find a cure? But all’ physical causes are partial at best. If you try to give someone a cold, for example, it takes more than a virus. Experimenters have incubated cold viruses, placed them directly on the mucous lining of the nose, .and found that their subjects came down with colds only 12, percent of the time. These odds could not be increased by exposing the subjects to cold drafts, putting their feet in ice water to give them chills, or anything else that was purely physical, Ordinary experience, a complex play of inner and outer forces, defies the rules of causation that work for billiard balls.

Conventional medicine already recognizes that ordinary experience can playa complex role in disease. For example, statistics show that single people and widows living alone are more likely to get cancer than people who are married. Their loneliness is called a risk factor one could just as truly call it a carcinogen. Then why isn’t curing loneliness a cure for cancer? It may well be, but in a different kind of medicine than we now practice. Ayurvedic physician is more interested in the patient he sees before him than in his disease. He recognizes that what makes up the person is experience sorrows, joys, fleeting seconds of trauma, long hours of nothing special at all. The minutes of life silently accumulate, and like grains of sand deposited by a river, the minutes can eventually pile up into a hidden formation that crops above the surface as a disease.

The process of accumulation is impossible to see or to stop. I may sit in a traffic jam and think, “Well, nothing is happening to me now,” but in fact I am taking in, or ingesting, the world around me. My body is metabolizing everything I see, hear, smell, and touch and turning it into me, just as surely as it ingests my orange juice. The input that is turning into me is constant, and by my participation I shape it into final form. Science will not be able to measure this process, because it cannot put my senses or my emotions on a scale. How much loneliness does it take to turn into cancer? This is a meaningless question. The carcinogen is invisible. I remember one night when I stood in the emergency room of a suburban hospital after attending to an , overflow of patients. A late commuter train had crashed, and with one other doctor I had to work in a near frenzy seeing dozens of passengers who might be in shock, bandaging their. wounds, calming their nerves, setting bones, and performing minor surgeries. Our job seemed endless, but after five hours it was done, and we felt like heroes.

Then the ambulance radio came on again, and the driver said. “We’re coming in with a two-month-old infant, female. who is unconscious. No signs of respiration or pulse, and she’s turning blue.” All at once I went cold, and I saw a look of despair on the other doctor’s face. We knew what was ahead of us. The ambulance unloaded its stretcher, bearing a tiny infant who looked lost on the big, white sheet. To put an end tracheal rube down her throat and begin cardiac massage was a horrible travesty, but we went through with it. From the first moment, we knew this must be a “crib death,” which medicine calls sudden infant death syndrome, It affects seemingly normal babies, there is no known cause, and even the fastest emergency treatment is usually of no avail.

As soon as we decently could, we rook away our apparatus and closed the baby s eyes. I went out to talk to the parents, young and well-to-do, who were devastated. All I could do was tell them about a support group of other parents whose children had died this way. They left, still in shock; and I never saw them again. Who can measure what happened to me? I don’t recall the face of a single victim from the train wreck, people whose bodies I worked on for hours. But the blond hair and blue eyes of the baby are as vivid in my mind as the first second I saw her. She has entered into me. I do not know where she lives inside me is it really some bit of gray matter in my cortex? It would seem ridiculous to look for the location. What is important is that my whole being is made up of such experiences. I have metabolized a hundred thousand such things every day, and if you want to see them in detail, just look at me.

As long as you are surrounded by the input of life, there is no stopping the rush of events that makes me what I am. On the other hand, my nature may go deeper than the things I see and hear. There may be a zero point in me, like the point of zero vibration which gives rise to the entire spectrum of light.

If you stepped outside my thoughts, senses, and emotions, you would be left with the equivalent of empty space. But like the empty space of quantum physics, my “inner space” may not be empty at all. I would argue that our inner space is a rich field of silent intelligence, and that it exerts a powerful influence on us. Intelligence is easily located and yet impossible to find. The body’s know-how seems to be the result of a complexity of parts, broken down according to functions digestion, respiration, metabolism, and so on. Although this division of labor is real enough, intelligence remains everywhere the same despite it, just as a drop of sea water shares the saltiness of the whole ocean. Sea water gives us a perfect example, in fact. The fluid in the body tastes as salty as the ocean and is equally rich in magnesium, gold, and other trace elements. Life began in the sea, and we are alive outside it only because we carry an internal ocean around with us. When you are thirsty and take a drink of water, you are actually rebalancing the fluid chemistry everywhere in your inner ocean.

The feeling of being thirsty is stimulated by the hypothalamus, a piece of the brain about the size of a finger joint, which in turn is connected by both nerves and chemical messengers to the kidneys. The kidneys constantly monitor the body’s need for water by “listening in” to signals from the blood. The signals are chemical, as with the neuropeptides, bur in this case the molecules involved are salts, proteins, and blood sugar, as well as specific messengers. The blood in rum is picking up these signals from every cell in the body, each of which is constantly monitoring its own need for water. In other words, when you want a drink of water you are not just obeying an impulse from your brain you are listening to a request from every cell in your body.

If you drink one small glass of water, you will replace only 1/400 of your total bodily fluid, yet that will satisfy the precise needs of 50 trillion different cells. Such exact monitoring is often attributed to the kidneys alone, but as we have Just seen, the kidneys never make decisions alone; they work in constant consultation with the quantum mechanical body the whole field of intelligence. The evenness of intelligence is not apparent from the physical makeup of the cells;. it coexists with the body’s extreme specialization. The neuron, which is outfitted on its cell wall with a million sodium-potassium pumps, is not at all like a heart cell or stomach cell. Yet, the integrity of the message “time for some water” is constant everywhere.

In physics, a field is what propagates an influence over a large, or even infinite, expanse of space. A magnet creates a magnetic field around
itself; small magnets have a weak field that extends a few inches, while ‘ the Earth’s magnetic poles are powerful enough to cover the entire globe. Anything that falls within a field feels its effect; ‘that is thy the magnetic needle of a compass aromatically aligns itself with the Earth’s
magnetic polarity. Sitting, in the body’s field of intelligence, each cell is aligned with the brain, which stands as the north magnetic pole.

A cell is a small Outcropping in the field; while the brain is a huge one. But the cell, when it “talks” to the rest of the body, is not inferior to the brain in the quality of what it says. Like the brain, it must correlate its message with trillions of others; it must participate in thousands of chemical exchanges every second; and most important of all, its DNA is the equal of any neuron’s. Therefore; the smallest impulse of intelligence is as intelligent as the largest. In fact, it is meaningless to speak of important pieces of intelligence or insignificant ones. We need only to remember the chain that builds dopamine; the inability co turn the humble protein serine into the equally humble metabolite called glycine leads to a minutely higher level of dopamine, with the catastrophic outcome of schizophrenia, overwhelming the entire mind.

Every cell is a little sentient being. Sitting in the liver or heart or kidney, it “knows” everything you know, but in its own fashion. We are of course used to the idea that we are smarter than our kidneys. The very concept of a “building block” implies that the brick is simpler than the building. That is true of a nonliving structure, but not of us. The nerve impulse for worry, for example, may show up in the stomach as an ulcer, in the colon as a spasm, or in the mind as an obsession, but they are various manifestations of the same impulse. Worry transforms itself from organ co organ, ye, each point in the body knows that there is worrying going on, and every cell remembers. You may consciously forget that you ‘are worrying, but then all at once the feeling is there to remind you, and it seems to be everywhere.

Earlier, we noted that if you could see the body as it really is, you would see it as constant change mixed with complete non-change. It is like a house whose bricks are constantly being replaced, or a sculpture
that at the same time is a river. The obstacle confronting medicine so far is that one side of our nature-the flowing and changing has been sacrificed for the sake of the other the stable and fixed. Now, having looked at the quantum level, perhaps we can package both into one unit that captures our real double essence the impulse of intelligence. An impulse of intelligence is the smallest unit chat preserves itself intact (non-change) while undergoing transformation (change). If impulses of intelligence did not have this one general property, then they could not be the basic building block of the body; either some purely mental impulse or some purely physical particle would have that distinction.

But neither of these can survive change. The molecules forming your brain on the day that you first thought the word rose are not there anymore, and yet the concept is. At the same time, you do not have to think the word rose all the time to retain it: you can think literally millions of other [thoughts without ever referring to this word. The next time you want it back, there it is, without confusion. It has retained its integrity through chick and chin because the impulse of intelligence contains mind, matter, and the silence that glues them together.

The physical structure of the body mirrors Intelligence and gives It projected form, bur intelligence is not travel inside this framework of flesh and bones. A startling confirmation of the face appears in the brain. Karl Lashley, a pioneer in neurophysiology, tried to discover where memory was located in the brain by performing a simple experiment with lab rats. He taught them to run a maze, a skill. that is remembered and stored .in their brains, just as we acquire skills. Then he systematically removed a small amount of cerebral tissue. Lashley supposed that if the rats still remembered how to run the maze (as measured by their speed and accuracy), then the brain’s memory center must still be intact

Little by little, he took our more brain matter, bur the rats, curiously enough, still remembered how to run the maze. Finally, more than 90 percent of the entire cortex was gone, leaving only a speck of brain tissue, and still the rats remembered the maze, with a slight fall-off in accuracy and speed. This experiment, among others, suggested a revolutionary idea, that every cell of the brain must Store the whole brain while at the same time storing its own specific task. This is exactly what we have found: every impulse of intelligence is equally intelligent, opening up endless possible projections of mind into body. John Lorber, a British neurologist, specialized in examining patients who were hydrocephalic in place of cerebral tissue, their brain cavities were filled with fluid. Generally, this condition, popularly called “water on the brain,” can be quite dangerous and lead to serious mental impairment.

However, one of Lorber’s patients was a gifted college student, majoring in mathematics, whose to was measured near 130. Referred to Lorber by his family doctor, who thought his patient had an enlarged head, the student was given a brain scan, which revealed that his cortex was only 1 millimeter thick, compared to the usual 4.5 centimeters. In other words, fluid had replaced about 98 percent of the neurons needed for thinking, remembering, and all the other higher functions centered in the cerebral cortex. With 2 percent of a normal cortex, this man was in the same position as Lashley’s rats, physiologically, and yet infinitely more capable he was in fact normal or above average in all respects.

We are being driven closer and closer to the silent field of intelligence as our fundamental reality. But once again, there is the problem that a silent mind seems to contain nothing at all. If we go back nearly a hundred years, a similar dilemma was very much in the air. A new science called psychology was trying to be born, but it was having a hard time because to qualify as a science, psychology needed an object to study. It was obvious that every person had a psyche, but no one had ever seen or touched one. The most basic questions about the psyche had remained unsettled for centuries. Was it the soul, the mind, the personality, or all three? No one was going to be able to set up the first experiment in psychology until these matters were settled.

The turning point came when William James, a brilliant philosopher at Harvard who also held a medical degree, asserted that psychology did indeed have a proper object to study. Or rather, thousands of objects all the thoughts, emotions, desires, and impressions that swirled through the mind. James called these the “stream of consciousness.” If there was a mental essence or soul, as pre-psychologists back to Plato had affirmed, then science could not find it. James did not say that such an invisible essence did not exist, but -he saw no way to experiment upon it scientifically

James defended the stream of consciousness on purely pragmatic grounds, reasoning that nothing in the mind could be considered tangible except the objects (thoughts) that passed through it. If one is always chinking or dreaming no one knows what he does mentally in deep nondream sleep then the reality of the mind must be simply a continuous flow of thoughts and dreams. James was a very astute observer; he had to be when you consider that he basically founded the field of psychology on the data he saw in his own head (as Freud did, extending the data into the field of dreams and unconscious motives). But James missed a tiny aspect of the mind that might have seemed completely trivial. The stream of consciousness is not made up solely of objects floating downriver; in between every thought there is a fleeting gap of silence.

It may be very tiny and all but unnoticeable, but the gap is always there and absolutely necessary. Without it, we would be thinking like this: “IlikethislunchanddessercbutifIeattoomuchohthereisSidIneedtowhereismywallet and so on. The silent gap between thoughts, being intangible, still plays no part in modern psychology, which is oriented completely to the mind’s contents or the brain’s mechanics. The gap turns out to be the central player, however, if you are interested in what lies beyond thought. ‘Every fraction of a second were permitted a glimpse into another world, one that is inside us and yet obscurely out of reach. A verse from an ancient Indian Upanishad describes this beautifully: A
man is like two doves sitting in a cherry tree. One bird is eating of the fruit while the other silently looks
all.” The bird who is the silent witness stands for that deep silence in everyone, which appears to be nothing at all when in reality it is the origin of intelligence.

The fascinating thing about intelligence is that it is like a one-way arrow: you can use Intelligence to shape a molecule, but if you look at the molecule, you cannot take the intelligence back out of it. When the poet Keats wrote his beautiful sonnet “To Sleep,” he began with the haunting line, soft embalmer of the still midnight.” If he had been hooked up to an EEG while he was writing, the readout of brain waves would have formed a unique pattern, yet no amount of examination of those brain waves could ever yield a line of poetry

In the same way, all of our molecules are hitched up with a bit of intelligence, which influences everything they do, but you cannot see it by looking at them. DNA provides a good example. Sitting in the nucleus or each cell, DNA is constantly bathed in a swirl of free-floating organic molecules, the basic building blocks of the material body. Whenever it wants to be active, ,D NA attracts these chemicals and uses them to form new DNA. This is an essential part of cell division–one
double strand of DNA must divide in half, splitting right down the middle like a zipper, and then each half turns into new, complete DNA by attracting the appropriate molecules to itself. The bath of swirling, aimless source molecules surrounding DNA provides it with “letters” to combine there are just four of them, labeled A, T, C, and G, for adenine, thymine, cytosine, and guanine. DNA spins these four letters out into an infinite variety of combinations, some of which are short (it takes three letters to code a basic amino acid), others of which are very long, like the poly-peptide chains that can be seen streaming away from DNA like tendrils. The DNA knows exactly what information to pick ant and how it all goes together for each thing it wants to “say” chemically. Besides building itself, DNA knows how to build RNA, or ribonucleic acid, which is its nearly identical twin and active counterpart. RNA’s mission is to travel away from the DNA in order to produce the proteins, more than 2, million in number, that actually build and repair the body. RNA is like active knowledge, in comparison to DNA’s silent intelligence.

DNA does not work just from rote memory. It can invent new chemicals at will (such as a new antibody after. you catch a strain of flu you have never been exposed to before), Exactly how this is accomplished is not known, although molecular biologists have found the spacers that separate different genetic words, or genomes. It is also well established that only 1 percent of the genetic material in DNA is used for its complicated coding, self-repair, and manufacture of RNA, leaving 99 percent doing nothing that science can account for.

This puzzling silence has stimulated a great deal of curiosity, especially among people who believe that humans do not use their full intelligence. William James ventured to guess that we use only 5 percent of our intelligence he meant mental capacity with an Einstein utilizing up to 15 percent or 20 percent. How this percentage translates into usable DNA is unknown, but we can venture to say that DNA is keeping a large vocabulary in silent storage one geneticist has calculated that the number of molecular “words” produced in a single cell, if translated into English, would fill a thousand-volume library. And that is the ‘product of just the active 1 percent we have managed to under- stand. Thanks to the discovery of recombinant DNA,(pieces of genetic material that can be shuffled in and out of sequence on the DNA strands), the potential vocabulary may be infinitely larger than we suspect; already the combinations of “letters” encoded on DNA are sufficient to create every life form on Earth, from bacteria and molds to ‘all plants, insects, mammals, and people.

One might suppose that the more complex the organism, the greater its share of DNA, but in fact a lily contains about a hundred times more DNA than a human being. Counting genes does nor give very much of a meaningful picture: the difference between man’s DNA and that of chimpanzees or gorillas is about 1.1 percent. This seems like a surprisingly small divergence, and a highly suspicious one. Can all the structural differences between a jungle primate and Homo sapiens, as well as
our vastly superior brains, be packed into such a tiny fractional difference? Evolutionists, having inherited Darwin’s faith in materialism, insist that it can. The issue is somewhat blunted when you realize, once again, that a gene count is not very significant two different kinds of fruit flies (Drosophila)
are much more closely related than man and chimpanzees, yet their DNA differs by considerably more.

Another way to show that our inner silence is alive and intelligent is to compare it to a machine’s. When a computer approaches a problem, it uses electrical impulses that must be separated from one another by gaps, forming a complex series of coded data out of 1 and 0. This enables the computer to handle any problem that can be broken down into information, since all information can be coded into 1 and 0, just as any message in English can be broken down into the dots and dashes of Morse code. The human brain also takes advantage of mechanically coded information, but the gaps in between are not just empty; they are the pivots that allow the mind to swing any way it wants. In other words, a computer has finite gaps made of emptiness; we have infinite gaps full of intelligence.

If you tell a computer to add 2 plus 2, it comes up with either a right or a wrong answer. If you ask a 5-year-old boy to do the same, he may come up with an arithmetical answer, hut he just as well might say, “I
want some vanilla ice cream.” We can assume that he is bored; perhaps he is too tired for an arithmetic article. So it is not correct to say that his response is a computational error; his mind is simply not under our control you cannot come up with a program to include all the possible reactions a human being can display as he interacts with the world.

What this all amounts to, in my mind, is a vindication of how complex ordinary experience really is, and how far away from life a scientific model is when it tries to describe it. The old view that the brain is a computer, stable in time and space, localized into various functions, and restricted in its flexibility, is unjustified. A Nobel Prize-winning neuroscientist, Dr. Gerald Edelman, has pointed out that the brain is much more like a process than a thing, and this process is continually evolving. It is true, for example, that memory depends on two small pieces of “hardware” on either side of the brain called the hippocampus; if both sites become damaged (through loss of blood flow or disease), the ability to recollect is destroyed.

Yet, within this physical limitation, each person’s brain is unique, both in structure and content. No two people have the same neuronal connections, and each person is constantly growing new ones from the moment of birth onward, giving rise to all the memories that make you and me totally different. (A connection does nor have to be physical; the flashing signals in the brain are constantly making patterns and reforming them into new patterns.)

Edelman holds that no one literally repeats a memory. When you recollect a familiar face, something will be different about it, if nor the face itself, then the context that caused you to remember, which may be sad now instead of happy. Memory is a creative act, then. It creates new images and new brain at the same time. Edelman theorizes that every experience one has in life changes the brain’s anatomy. Therefore, it is not wholly true to say that the hippocampus is the sear of memory, for anyone memory the first day you saw a field of daffodils shifts and shimmers across your entire cortex, touching other memories here and there, passing into new interpretations, and having to be re-created every time you need to recollect it. Unlike any computer, we remember, reconsider, and change our minds. The universe was created once, bur we re-create ourselves with every thought.

Everything, in short, depends upon how well you can build in silence. Whatever can be experienced on the surface of life love or hate, disease or health-wells up from a deeper level and floats above it as little more than a bubble. One can try to prick the bubbles one by one, but they float up from below unendingly. If we want to navigate the field of intelligence, we must learn about it to the very depths, where the silent witness inside us waits. That is our next step. to map the inner silence and master its secret places.

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Nowhere And Everywhere

October 27, 2009 Uncategorized

No one will ever see the quantum mechanical body. For many people, this will be a problem. Not just scientists ‘but all of us are computable with things we can see and touch. The history of modem medicine consists largely of tracking down solid objects that cause disease, a1- ·though almost all of them dwell in the realm of the invisible, beyond anything the naked eye can perceive.

A canny observer in fourteenth-century Europe might have conjectured that a rat in the house portended the danger of bubonic plague (in
actuality, rats were so common that the connection was never made); spotting a flea on the rat’s pelt gets one closer to the actual cause, but only when you investigate the rat’s blood under a microscope and find the bacterium Pasteurella pestis
have you actually solved the riddle of
the Black Death, a nemesis of mankind so ancient that it is credited with decimating the Persian army when it marched against Greece in the fifth century B.C.

Without a microscope, what would a bacterium be? Something invisible to the eye and yet as big as the world, since it reaches every locale on Earth, even the poles. It would come and go like smoke penetrating the tightest sealed doors and windows if you believed only in your senses, the ability of such an organism to be nowhere and everywhere at the same time would seem fantastic. In essence, the quantum world is but another step down on the scale of invisibility. Unlike the tiniest bacteria or viruses, a single photon, electron, or any other object in the quantum world can never be seen using any extension of sight and touch. They are truly everywhere and nowhere at the same time.

This fact hardly concerned medicine until very recently, because the smallest virus is still many millions of times larger than an elementary particle. Also, germs are quite stable in time and space, while quantum objects wink in and out of existence unpredictably. If Pasteurella pestis
lurks in your blood, it is there, absolutely and definitely, unlike the ghostly mesons that leave faint flashes on a photographic plate for a few millionths of a second, only to vanish out of material existence, and most unlike the neutrino, which can pass undetected through the entire Earth as though nothing stood in the way.

The vast difference in scale between medicine and quantum physics safely kept the two sciences on separate ground until 1987, when a French immunologist, Jacques Benveniste, performed an experiment that is outrageous to all nonquantum views of the world. On the surface, the experiment began innocuously. Dr. Benveniste took a common antibody called lgE (standing for immunoglobulin E type) and exposed it to certain whire cells in die blood called basophils. It is well known what happens when these two interact the IgE antibody clamps on firmly to specific receptor sites and waits. What it is wairing for is an invading molecule floating by in the bloodstream that needs to be defended against. In this case, the invader is not a germ but an antigen, a substance that causes allergies.

If you are allergic to bee sting, the molecules of bee venom would not be in your body more than a few seconds before they triggered the IgE antibody. It in turn would set off a complex chain reaction in the cell that throws the body’s allergic response into high gear; the basophil would release achemical called histamine, which causes the swelling, redness, itching, and shortness of breath typical of an allergy attack. The mystery in allergies is that the antigens, the offending substances entering the body, are generally harmless woo!, pollen, dust and yet the immune system treats them like the deadliest enemy. To find their cause, allergies have been ,thoroughly studied at the molecular level, and one of the results is a .firm grasp of IgE.

This sets the stage for Dr. Benveniste’s dramatic experiment. He took some human blood serum full of white cells and IgE and mixed it with a solution prepared from goat’s’ blood that was certain to trigger the release of histamine. This second solution contained an anti-IgE antibody, which represents bee venom, pollen, or other antigen. When the IgE and the anti-IgE hit, the reaction in the test tube went off exactly as it would in a person with a bad allergy, and large amounts of histamine were produced.

Benveniste then diluted tbe anti·lgE tenfold and added it again still the same reaction. He, kept on di luting, time after time, and as before, about half of the IgE (40 to 60 percent) ,continued to react. This was extremely surprising, because be was well past the limit where the solution should be chemically active. He decided to dilute the anti-IgE even more, making it a hundred times weaker each time, until be knew that there was no anti-IgE at all. His last dilution contained 1 part antibody to 10120 parts water; if written out, this number would be expressed ‘ as 10 followed by 120 zeroes. Using a constant called Avogadro’s number, be confirmed mathematically that it was impossible for the water to
contain” single molecule of antibody. When he added this “solution,” which was now just distilled water, the histamine reaction was set off with the same power as before. (The classic Humphrey Bogart movie, To Have and Have Not, contains the quirky line, “Have you ever been stung by a dead bee?” In, this case, the bee is also invisible.).

Although his result was an absurdity, Benveniste duplicated it seventy times. and asked other research teams to repeat it in Israel, Canada, and Italy all came up with the same result. They all discovered that you can trigger the immune system with an antibody that isn’t there. In our terms, Benveniste had uncovered the ghost of memory he himself speculates whether water contains the phantom imprint of the molecules that were once in it. His results were reluctantly published in the June 1988 issue of the prestigious British journal Nature. Its editors frankly declared their repugnance at the result, staring quite rightly that “there is no physical basis’ for it. The human white cells were acting as if the anti-IgE was attacking them from everywhere when in fact it was nowhere.

Medicine is reluctant to walk through the quantum door, even though this experiment clearly opens it.
It was widely held that Benveniste was lending credence to the methods of homeopathy, a medical system invented two hundred years ago by a German physician, Samuel Hahnemann, and still popular throughout Europe. The term homeopathy comes from two Greek roots that mean “similar suffering”; this points to the fundamental homeopathic principle that “like treats like.” Homeopathy approaches all diseases using Benveniste’s method: tiny amounts of antagonistic substances’ ace taken by the patient to build up immunity or to drive out a disease if it is already present. When conventional medicine administers a smallpox vaccine, it appears that homeopathic logic is at work the dead virus in the vaccine stimulates anti-smallpox antibodies in the body. (This method of fighting smallpox goes back to ancient China, where doctors knew to take scabs from the sores of smallpox victims and rub them on small cuts in the arms of those they wanted to protect from the disease.) Unlike vaccination, however, homeopathy is based on symptoms rather than on the actual organisms that cause a disease.

Using an elaborate system of poisons and toxic herbs that mimic the symptoms of true disease, the homeopath gives the body a taste of what he wants to cure. Ground-up Nux vomica seeds, for example, which contain strychnine, would be given to counteract chronic fatigue and irritability, because they produce these symptoms themselves. Benveniste’s experiment in fact did not endorse homeopathic logic as a whole but only a corner of it, by showing that the body can react to a microdose of a foreign substance.

The rest of homeopathy remains ambiguous. (The principle of “like treats like” is accepted in Ayurveda, and even broadened to say that every part of the body is matched by herbs, minerals, and even colors and sounds that can be used to treat it. However, Ayurveda does not follow the homeopathic logic that the. body should be made sick in order to make it well) The deeper import of Benveniste’s experiment, I believe, is brought out by one
the quantum diagrams from the last article: A bodily process, we noted, is like a bucket brigade, a chain of events passing from one step to another, with the exception of the first bucket (B). This bucket appears as if out of nowhere, even though we can obviously see that it is triggered by some initial impulse (A). What Benveniste did so beautifully was to strip this model down to its barest essentials:

We continually cross over from the state of no molecules to one. If you try to remember the first time you ever drove a car, the brain chemicals present on that occasion have by now vanished. (Most of them disappeared before the drive was over.) When you re-create that memory today, seeing the car and feeling the steering wheel in your hands, you are triggering cellular reactions that begin “nowhere,” since your brain cells are as empty of the old molecules as Benveniste’s water. If you can explain how the body-mind gets from no molecules to one, then a great many mysteries about the brain will be cleared up. After that first tiny bit of matter, the rest of the sequence follows laws of nature that are well known. Aside from homeopathy, I see a much clearer example in the strange psychiatric cases known as multiple personalities. Nothing in the mind-body field seems quite so inexplicable, for when a person with multiple personalities shifts from one to the other, his body shifts too.

One personality might have diabetes, for example, and the person will be insulin-deficient as long as that personality is in force. Yet the other personalities may be completely free of diabetes, recording the same blood sugar levels as a normal person. Daniel Goleman, a psychologist and frequent reporter on mind-body topics, describes a child named Timmy who adopts nearly a dozen separate personalities. One of these breaks out into hives if he drinks orange juice. “The hives will occur,” Goleman writes; “even if Timmy drinks orange juice and another personality appears while the juice is still being digested. What is more, if Timmy comes back while the allergic reaction is present, the itching of the hives will cease immediately, and the water-filled blisters will begin to subside.”

When I first read these words, I felt very excited. Medical texts do not say .hat allergic reactions can be turned off and on at will. How could they? The white cells of the immune system, coated with antibodies like IgE, merely wait for the contact of an antigen. When contact occurs, they are automatically triggered to react. Yet, in Timmy’s body, one has to envision the orange-juice molecules approaching the white cell, and then a decision is made whether to react. This implies that the cell itself is intelligent, just as I have been arguing. Moreover, its intelligence is wrapped up in every molecule, not doled out to a special one like DNA, for the antibody and the orange juice meet end to end with very ordinary atoms of carbon, hydrogen, and oxygen.

To say that molecules make decisions defies current physical science it is as if salt sometimes feels ‘like being salty and sometimes not. Bur to cross over from one event in the body-mind to another is always a projection of intelligence; it is only the remarkable swiftness and intensity of Timmy’s case that stuns us. Once we absorb the fact that he is choosing to be allergic for how else could he turn his hives off and on? then we confront the possibility that we, too, are choosing our own diseases. We are not aware of this choice, because it takes place below the level of our conscious thoughts. But if it is present, we should be able to change It. All of us can shift the biology of our bodies from one extreme to the other. When you are wildly happy, you are not the same person, physiologically speaking, as when you are deeply depressed. The multiple personalities demonstrate that this ability to change from the inside is under precise control. I’d like to relate a bit of Chopra family lore that relates to this and also, curiously enough, to the IgE antibody.

My father is a cardiologist in India. For many years he served as an army doctor, which required us to move from post to post throughout the country. While I was an infant, he was sent to Jammu, far away to the north in the state of Kashmir. I remember nothing of our stay there, but for years I heard about the terrible allergies my mother suffered in that place. Her tormentor was the pollen of a native flower that covered the ground when it blossomed every spring. It caused her to have severe asthma attacks; her body swelled, and on her skin appeared large red welts and blisters (her condition is known as angioneurotic edema). My father is very ‘devoted to my mother, and out of compassion he drove her every spring to Srinagar, the capital of Kashmir. The air in Srinagar is free of this particular pollen, and she was delighted to find herself in
mountain valley that is one of the most beautiful places on Earth.

One spring the heavy rains had made the road impassable, and my father decided that they should fly back home early. They boarded the plane, and after an hour it touched down. He put his hand reassuringly on my mother’s arm, but he could already see the red spots on her skin and the effort it took for her just to breathe. My mother’s allergy was so severe that the steward ran up and asked what was wrong.

“There’s nothing you can do,” my father said. “It’s the pollen in Jammu.” “Jammu’” The steward looked puzzled. “We haven’t landed there yet -this is Udhampur, our first stop. Didn’t they tell you?” My father was quite startled. When he looked at my mother, her wheezing had subsided and her sores were vanishing on the spot. For years afterward he would shake his head and mutter, “All you have to do is say the word Jammu and your mother breaks out.” When I told him about the IgE experiment, he was very relieved now he had a scientific answer, of sorts, to our family mystery. My mother has only one personality, but this shift was both extreme and swift.

Many multiple-personality cases have been studied and verified, particularly by Dr. Bennett Braun, a research psychiatrist and specialist in the field. When the patient’s personality shifts, warts, scars, and rashes have been seen to appear and disappear, along with hypertension and epilepsy. A specific personality can be color blind, only to return to normal sight when the personality changes back. Almost as a rule, such patients have at least one personality that is a child, and when it emerges, their bodies respond to lower doses of drugs. In one case, 5 milligrams of a tranquilizer are the patient relaxed and sleepy when he was a child, while a dose twenty times stronger had no effect on the adult.

Mystified researchers are looking for a mechanism to explain these seemingly impossible occurrences; it will be found, I believe, only by seeing that a quantum shift has taken place. A personality has no molecules in it, being composed only of memories and psychological tendencies; yet these are more permanent than the cells being affected. This is not a huge mystery every molecule in your own body is wrapped up, as we saw, with a bit of invisible intelligence.

Memory is not a term used by physicists, and yet it is easy to find it in the quantum world particles that are separated by immense distances of space-time know what one another are doing. When an electron jumps into a new orbit on the outside of an atom, the anti-electron (or positron) paired with it must react, no matter where it lives in the cosmos. In fact, the entire universe is knitted together by this kind of memory network.

To a physicist, the only puzzle in Benveniste’s experiment is that no one has ever believed that quantum events take place at the level of molecules. A photon sits on the quantum threshold, where faint, random vibrations are the rule. Some of these vibrations die off into nothingness; others wake up and enter material reality as matter or energy. Because the photon is almost nothing to begin with, it can wink in and out of existence. A molecule like IgE, however, is tremendously more substantial than these fluctuating vibrations. If it weren’t, molecules might jump in and out of existence without warning along with things made our of molecules, like blue whales and skyscrapers. Since this does not happen, it has not been deemed necessary to invest molecules with memory.

To understand how such memory works, one has to know more about the quantum level of nature. Its peculiarity, setting it aside from all other states ‘of matter and energy, is its emptiness. We have already seen that at its heart, an atom is almost totally empty, being proportionately as void as inter-galactic space. The same must hold true for us, since obviously we are made of atoms. That means we are made out of a void; more than anything else, it is our “raw material.

Instead of seeing the space among the stars as bleak, cold, and lifeless, one should look through a physicist’s eyes and see it packed with unseen energy waiting to coalesce into atoms. Every cubic centimeter of space teems with energy, nearly infinite amounts of it, although much of this energy is in “virtual” form, meaning that it is locked up and plays no active Part: in material reality. (A wonderful line from an ancient Indian Upanishad declares, “The power penetrating the universe is much more than what shines through.” In terms of quantum objects, most of which are locked up in virtual form, this is true literally.)

Our senses are not prepared to see emptiness as the womb of reality, being tuned in to a grosser level of nature populated with flowers, rocks, trees, and our families. It is said that the human eye can distinguish 2 million shades of color, each of which occupies a narrow band of light energy, bur our optical mechanism nevertheless doesn’t register these energy vibrations as vibrations. Much less do we register a chunk of solid marble as vibrations, although at bottom that is what it is, Just the same as color.

As light shifts from color to color, each small gradation exerts an enormous influence. Visible light, for example, gives the world shape and definition as perceived by our eyes. If you shift down just slightly to the infrared band, the human eye would feel warm from the light but be blind;)f you shift up to X rays, the eye would be destroyed. Every quantum gradation is slight, but it implies a completely new reality at the grosser level of molecules and living things. The spectrum of light is like a long, continuous string, vibrating slower at one spot and faster at another. We make our home on a tiny part of the spectrum, but it takes the entire length for us to exist. Beginning at zero vibration, shakes of the suing are responsible for the light, heat, magnetism, and countless other discrete energy forms that fill the universe. It is just a few steps on the ladder of creation from empty space to inter galactic dust to a sun and finally the living Earth. What this shows is that emptiness, the point of zero vibration, is not a void but the starting point for everything that exists. And this starting point is always in Contact with every other point there are no breaks in continuity.

The reason for discussing the subatomic void is that we experience the void every time we think. Just as in the universe at large, something material the neuropeptide springs our of nowhere. In this case it is not the atoms of the neuropeptide that are created, because the necessity hydrogen, carbon, oxygen, and so forth are already present in the glucose that the brain uses as fuel. What is created out of nowhere is the configuration of the neutopeptide, but that is magical enough.

At the very instant that you think, “I am happy,” a chemical messenger translates your emotion, which has no solid existence whatever in the material world, into a bit of matter so perfectly attuned to your desire that literally every cell in your body learns of your happiness and· joins in. The fact that you ·can instantly talk to 50 trillion cells in their own language is just as inexplicable as the moment when nature created the first photon out of empty space.

These brain chemicals are so small that it has taken science several centuries to identify them. Yet if we look at the messenger molecules as being the finest material expression of intelligence the brain can produce, we have to admit that they are still not quite fine enough to build a secure bridge between mind and body. In fact, nothing could be fine enough, because one shore we want to bridge, the mind, is not small in any physical sense to think that a thought has a size is absurd. Mind is not “hanging out” in space taking up room, even the infinitesimal room needed for an electron. The obvious nonsense of putting mind into a box was one of the chief reasons. why science separated mind and matter to begin with, ·since all matter can fit into a box. Fortunately, quantum physics comes to the bridge builder’s rescue. It was born to explore these nonsensical-seeming regions on the fringes of space-time. Quantum physics has taken responsibility for measuring things that are as small as possible. The atom, although very small, was found around 1900 to have a nucleus, and when that was sliced apart, its smallest, unit seemed to be the proton, until further atom-smashing revealed, at the edge of material existence, still finer particles called quarks. Beyond the quark, however, the smashing seems to stop.

One would think that there has to be something material out there that the quark is built from. Strangely enough, this does not seem to be true. In ancient Greece, the philosopher Democritus first proposed that the material world was composed of minute, invisible particles, which he named atoms, from the Greek word for “not divisible.” When Plato heard of this theory (which of course could not be tested experimentally), he offered an objection that uncannily predicts quantum physics. If we think of an atom as a thing, Plato argued, then it must take up some space; therefore, it can be cut in half to occupy a smaller space. Anything that can be Cut in half is not the smallest constituent of the material world.

By this impeccable reasoning, Plato demolished all solid particles as contenders for nature’s basic building block, not just the atom, but the proton, electron, and quark. All of these can be cut in half, even if we can’t actually do it, without end. Whatever it is that builds the world, it must be something so tiny that it occupies no space. Plato contended that the world was born out of invisible, perfect forms, similar to geometric shapes. In its turn, modem physics has turned to somewhat more tangible alternatives, such as invisible matter called “virtual” particles, as well as to energy fields. Einstein’s famous equation E = mc2 proved that energy could be transformed into matter, and this allowed physics to go beyond the barrier that is “smaller than small”

No one can confidently say what builds a quark, but it is certainly not a piece of matter in solid form the quark is already outside the limit of anything that one can “see” or “touch,” even using scientific instruments to extend our senses; its building block may well be merely a vibration that has the potential to rum into matter. Therefore, it is smaller than small To a physicist, all size stops at a specific number, 10- 33 cubic centimeters, an inconceivable fraction that can be written out as 1/10 followed by 32 zeros; this is known as Planck’s limit, a kind of absolute zero for space, just as there is an absolute zero for temperature.

Once this barrier is reached, however, what lies beyond? Here physical science stands mute. Bur it is fascinating to discover that all the founders of quantum physics were basically Platonists. That is, they believed that the world of things is a shadowy projection of a vaster, invisible reality that is nonmaterial. Some, like Einstein, stood in awe at the orderliness of nature without ascribing intelligence to it. Others, like Eddington, flatly declared that the raw material of the whole universe is “mind-stuff.” Eddington defends his position with a logical argument as elegant as Plato’s. Our picture of the world, he points out, is basically a formation of brain impulses. This is formed in turn our of impulses traveling up and down the nerves. These in turn come from vibrations of energy at the ends of the nerves. At the basis of the energy is emptiness, the quantum void. Which part is teal? The answer is none, because every step along the way, from energy vibrations ‘0 nerve impulses to brain formation, is just a code.

No matter where you look, the visible universe is fundamentally a set of signals. Yet these signals all hold together, turning totally meaningless vibrations into full-blown experiences that have human meaning. The love between man and wife can be broken down into raw physical data, but to do that is to lose its reality. Therefore, Eddington says, all these codes must stand for something more real, something beyond our senses. At the same time, this something is very intimate to us, for all of us can read the code, turning random quantum vibrations into an orderly reality.

A good image for this would be a pianist playing a Chopin etude. Where is the music? You can find it at many levels in the vibrating strings, the trip of the hammers, the fingers striking the keys, the black marks on the paper, or the nerve impulses produced in the player’s brain. But all of these are just codes; the reality of music is the shimmering, beautiful, invisible form that haunts our memories without ever being present in the physical world.

To be like the quantum, the body does not have to banish its molecules to another dimension; it has only to learn ‘ to re-form them into new chemical patterns. It is these patterns that jump in and out of existence, paralleling what happened in Benveniste’s test tubes. If you think hard about leaping off a cliff and your heart starts to pound, you have generated adrenaline using a stimulus that is Just as invisible as the anti-IgE in the experiment. Similarly, one of Timmy’s personalities remembers how to be allergic to orange juice, even though that personality may hide in some invisible realm for days at a time. As soon as it returns, the body must obey its commands.

I have tried to make all of this sound reasonable, contrary to one of the editors at Nature, who said that the IgE experiment, if true, throws out two hundred years of rational thought in biology. But biology will have to change now, and medicine with it. Contrary to what physicians currently suppose, the abnormal pancreas of a diabetic is not as real as the distorted memory that has wrapped itself inside the pancreatic cells.

This realization opens the door for quantum healing. The mental techniques used by Ayurveda depend on being able to control the invisible patterns that order the body. Recently I saw a patient, an elderly women who was suffering from dull chest pains; they had previously
been diagnosed as angina pectoris, one of the most common symptoms of advanced heart disease. Between January and May of that year, she had recorded sixty attacks of angina, which were relieved by taking a nitroglycerine tablet. I instructed her in the “primordial sound technique” fur heart disease, and she left to practice it on her own.

In July, about two months later, my patient wrote me a letter starting that her attacks had stopped on the day she received the technique and have never recurred. She feels comfortable in activity now most angina sufferers are extremely anxious about exerting themselves, even slightly. On her own she has discontinued the use of her medication, and she recently enrolled as a full-time college student. She was very proud to write this last piece of news, since she is 88 years old.

In my own mind, I explain this result by saying that the mind-body connection is coming under control. I would also say that the Ayunedic technique is not magical; it is only imitating nature. Is there any difference between my patient making her angina disappear and a multiple personality doing the same thing?

A skeptical doctor might object that angina usually has two causes. One is spasm of the coronary arteries, the blood vessels chat feed oxygen to the heart. If these go into spasm and squeeze shut, then the oxygen deprived heart muscle screams out in ‘pain. My patient must have had this kind of angina, a skeptic would say. The other kind is caused by fatty blockages in the coronary arteries and couldn’t possibly be cured by a mental technique. I would have to answer that both examples involve memory. The fatty blockages are not as substantial as they appear. If you perform a heart-bypass graft and replace the old clogged arteries with open ones, the new replacements will often clog up in a matter of months. This is because the vessel has changed but the ghost of memory has not it still wants to load fatty plaque into that artery.

On the reverse side, many bypass patients don’t feel the return of their agonizing, frightening chest pain, even with clogged arteries, because they are sure that their surgery cured them. Surgeons have even experimented with placebo operations, doing nothing more than the chest and closing it again a good percentage of those patients felt relief from their angina. In fact, my patient did not have blocked coronary arteries, but the mechanism behind her angina was physically real nonetheless; her brain did not X-ray her blood vessels before reacting with pain.

If I have a patient who is afraid, I can grasp his hand reassuringly and he will feel better; this happens even under anesthesia. You can grasp the patient’s hand at a difficult moment in surgery and see the monitors fur blood pressure and heartbeat register the calming effect. The heart and the brain, it ·seems, are connected much deeper than where molecules are. One sees the truth of this whenever a baby is cradled in its mother’s arms. Within a few minutes the two of them will be breathing together, even if the baby is asleep, and their heartbeats will start to synchronize (they will not match beat for beat, since the child’s heart rate is faster , than .the mother’s). This body-mind connection is invisible, but who would call it unreal? It has been passed on silently from generation to generation. Perhaps it still wraps us all in a bond of sympathy. Out of separate beings, trapped in their own concerns, it helps to mold one human race.

Once science recovers from its shock over the IgE experiment, a new domain will need to be explored, the domain of emptiness. Quantum physics has discovered· something mysteriously rich about empty space. Now we are on die verge of extending this richness into the human dimension.

The universe in its primordial state has been likened to energy soup that turned into particles of matter. I would liken us, then, to intelligence soup except that we aren’t soup at all but intelligence that has learned to crysra11ize into beautiful, precise, powerful, organic particles we call thoughts. This makes the void inside us far more fascinating than the one that gave birth to the universe.

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The Quantum Mechanical Human Body

October 26, 2009 Uncategorized

Ninety years after they began to emerge, the insights of quantum physics remain a total mystery to most people. Yet, once you understand what the discovery of neuropeptides means, then the: quantum is only a step further. The discovery of neuropeptides was so significant because it showed that the body is fluid enough to match the: mind. Thanks to messenger molecules, events that seem totally unconnected such as a thought and a bodily reaction-are now seem to be consistent. The neuropeptide isn’t a thought, but it moves with thought, serving as a point of transformation. The quantum the same thing, except that the nature as a whole.

We need to consult the quantum to really understand how the: mind pivots on the turning point of a molecule. A neurrpeptide into existence at the touch of a thought, but where does it spring from? A thought of feat and the neurochemical that it turns into an: connected in a hidden process, a transformation of nonmatter into matter thing happens everywhere in nature, except that we do not call it thinking. When you get to the level of atoms, the landscape is not one of solid objects moving around each other like partners in a dance, following predictable steps. Subatomic particles are separated by huge gaps, making every atom more than 99.999 percent empty space. This holds true for hydrogen atoms in the air and carbon atoms in the wood that tables are made of, as well as all the “solid”‘ atoms in our cells. Therefore, everything solid, including our bodies, is proportionately as void as inter-galactic space.

How could such vast reaches of emptiness, dotted at faraway intervals by specks of matter, turn into human beings? To answer that question requires a quantum perspective. By understanding the quantum, we enter into a vaster reality, spanning from quarks to galaxies. At the same time, the behavior of quantum reality turns out to be very intimate to us -indeed, the faintest shadow-line separates the human body from ‘ the cosmic body.

In his monumental project to make all of physics follow a few consistent, rational laws, Isaac Newton explained nature’s workings in terms of solid bodies, straight-line motion, and fixed constants that ruled all physical events. This is the model of nature as a complex billiard game. with Newton as the master player. Because matter and energy stayed within set rules, there was no need to theorize about a hidden world everything happened aboveboard. We can express this idea with a simple diagram:”

Here, A is a cause and B is an effect. They are joined by a straight line, expressing that cause and effect are logically connected in the world we are familiar with, the world of the senses. If A and B are two billiard balls, making one hit the other is a predictable event. However, if A is a
thought and .B is a neuropeptide, then the diagram would · not apply. There is no straight-line connection between a nonmaterial thought and a material object, even one as small as a peptide molecule. Instead, one has to draw a different diagram with a detour in it:

The U shape shows that a process has to take place that is not above the line, in Newton’s rational, straight-line world. There is some hidden transformation happening that turns a thought into a molecule. The transformation doesn’t take any time and doesn’t happen in any place it is carried out just by the presence of an impulse of the nervous system. When you think the word rose, a large number of brain cells have to fire (no one knows how many, but let us say 1 million, which is probably absurdly small), but these cells don’t get in touch with one another by passing a message from A to B to C, and so on, until all 1 million get the message. The thought just appears, suddenly localized in time and space, and with it, the brain’s cells all change in sync. The perfect coordination of this thought-event and 1. million brain cells making neurotransmitters must have happened below the line. The whole area below the line is note region to be visited in space and time; it just stands for wherever it is you go when you turn thoughts into molecules.

One could al so think of it as the control too, m that correlates any mental impulse with the body. At anyone time, all 15.
billion neurons in the nervous system are being co-ordinate with perfect precision from below the line. The same change from straight-line causes to U-shaped detours occurred
when quantum physics was born. Although everything in nature once appeared to happen above the table, according to classic Newtonian theory obviously, physicists leave mental events out of the picture a few things could not be explained without a detour. The most obvious was light. Light can behave like A, a wave, or B, a particle. These two totally unalike in Newtonian physics, since waves are nonmaterial and particles are concrete. But light somehow can act like one or the other depending on circumstances, and therefore it must have taken a detour under the line:

To light ,as a wave, or vibration, is easy enough. A prism breaks White light down into the colors of a rainbow; the reason for this is that white light is composed of separate wavelengths of light, a fact that becomes apparent when light bulb has its own spectrum of wavelengths, when electricity passes through the tungsten filament. But if you turn the light down with a dimmer switch until just the smallest amount of light can come out, it will come out not like a wave but like a panicle. (No dimmer switch is this fine-tuned, but physicists have broadcast light so that it exposes ‘its “graininess.” Nature has also quipped our eyes to respond physically to light at its quantum level if only a single photon falls on the retina, a Bash is transmitted along the optic nerve. Our brains, however, do not process just one Bash.) The word quantum
from Latin for “how much?” describes the Smallest unit that can be called particle like. A photon is a quantum of light because you cannot split it .into finer particles, The photon manifests when a Bow of electrons its a tungsten atom; the moving electros
in the electricity collide with electrons whirling in orbit around the outside of’ the tungsten atom, and out of their collision jumps a photon, a quantum of light. This quantum is a very strange particle, because it has no mass, but for Out purposes, what makes it important is that in order for a light wave to become. a photon, it must take a detour beneath the table. In an unknown realm not covered by Newton’s laws, the transformation takes place.

Since we are not trying to explain physics here, I won’t go into elaborations. It is enough to know that after Einstein, when Max Planck
and other pioneering physicists at the turn of the century were able to demonstrate’ the quantum nature of light, many, many cautious conclusions resulted. Events that we take for granted in the world of the senses had to be reconciled with strange distortions of time and space but reconciled they were. As with the neuropeptide, the quantum allowed nature to become flexible, enough to permit the inexplicable transformation of nonmatter into matter, time into space, mass into energy. Here is the pattern for a basic quantum. event; it shows the detour that always takes place outside the reach of ordinary events:

Like the thought and the neuropeptide, light cannot” be a wave and a photon “at the same time; it is either one or the other. Yet it is obvious that a tungsten light bulb doesn’t enter another reality when you turn it down. Somehow; nature sets up its laws so that light can be either A or B, and both are kept inside the boundaries of the same reality by building in a transformation point. (People today still casually assume that Einstein over threw Newton, when in fact he saved Newton’s belief in perfect order by expanding it.)

A strikingly elegant view of mind and body can be formed from this basic quantum event, requiring only one diagram: The mind and the body are both above the line. A is a mental event, or thought; all the other letters are physical processes that follow from A. If you feel afraid (A), then the other letters stand for signals to your adrenal glands, the production of adrenaline, the pounding of your heart, elevated blood pressure, and so on. These are B, C, D, et cetera. All the physical changes that take place in the body can be connected in a logical chain of ‘Cause and effect, except for the space after A. This is the point where the transformation from thought to matter first occurs: and it must occur, or the rest of the events will not happen.

At some point in the lineup, there must be a detour. At that point, the lineup breaks down, because mind does not touch matter above the table. If you want to lift your little finger (point A), a physiologist can trace the neurotransmitter (B) that activates an impulse that runs down the axon of the nerve· (C), causing a muscle cell to respond (D), resulting in the lifting of your little finger (E). However, nothing a physiologist can describe will get him from A to B it requires a detour. The whole picture is like a bucket brigade, where each fireman gets his
bucket from the fireman before him, except for the first, who gets his from nowhere.

“Nowhere” is almost an exact term here, because you cannot subdivide the body to arrive at the precise junction where a thought turns into molecule, any more than you can find the station house where photons are fashioned into light waves. What exactly happens in the? zone is not known, either in physics or in medicine. Miraculous cures seem to be examples of dipping into the? zone, because the cooperation of mind and matter takes an inexplicable quantum leap in such cases, but so are other mind-body dramas that play themselves out in mysterious ways. ,

Several years ago, a Boston fireman in his mid-forties came into the emergency room of a suburban hospital one night complaining of sudden, sharp chest pains. The resident on call examined him and could find no evidence of irregularity in his heart function. The patient went away without being reassured, and soon he returned with the same symptoms. He was turned over to me as senior physician, but I could find nothing wrong with his heart, either.

Despite his thorough examination, the fireman began to return to the ER repeatedly, usually late at night. Every time he came in, he told me with great trepidation that he was certain he had a heart condition, but no test, including the most sophisticated echocardiograms and angiograms, detected the slightest defect. Finally, in the face of the man’s mounting anxiety, I recommended that he be retired with full disability purely for psychological reasons. The fire department’s medical examining board refused, on the grounds that no physical evidence had been offered. Two months later, the man showed up one last time at the emergency room, this time on a stretcher, the victim of a massive heart attack. Within ten minutes of his coronary, which destroyed 90 percent of his heart muscle, he died, but he had enough strength to turn to me and whisper, “Now do you believe I have a heart condition?”

What this case so dramatically attests is that the detour into the? zone is powerful it can change any physical reality in the body. I feel I must call what happened here a quantum event, because it did not follow the cause-and-effect rules that have been observed and set down by medicine as the body’s normal state of affairs. Many people entertain fears that they might have a heart condition, but they don’t die from them; conversely, many heart attacks occur without the slightest forewarning from the mind. Even if we say, in keeping with mind-body medicine, that a thought caused the heart attack, how did this thought find a way to carry out its fatal intention? If you program the concept of “heart attack” into it computer, you know exactly what you have done. If you want to retrieve it, the circuits can be activated to bring it up to the screen, and once it is there, you can use son ware to manipulate it. But the thought “heart attack” didn’t act like this at all in my patient. He didn’t know where the thought came from; once it came, he was powerless to escape it; and far short of staying in one place, the thought invaded his body, with disastrous results.

This is only half of the mystery of a quantum event the negative half; the journey into the> zone can have amazingly positive results, too. Another patient of mine, a quiet woman in her fifties, came to me about ten years ago complaining of severe abdominal pains and jaundice. Believing that she was suffering from gallstones, I had her admitted for immediate surgery, but when she was opened up, it was found that she had a large malignant turn
that
spread to her liver, with scattered pockets of cancer throughout her abdominal cavity. Judging the case inoperable, her surgeons closed the incision without taking further action. Because the woman’s daughter pleaded with me not to tell her mother the truth, I informed my patient that the gallstones had been successfully removed. I rationalized that her family would break the news to her in time, and that in all likelihood she had only a few months to live at least she could spend them with peace of mind.

Eight months later I was astonished to see the same woman back in my office. She had returned fur a routine physical exam, which revealed no jaundice, no pain, and no detectable signs of cancer. Only after another year passed did she confess anything unusual to me. She said, “Doctor, I was so sure I had cancer two years ago that when it turned out to be just gallstones, I told myself I would never be sick another day in my life.” Her cancer never recurred.

This woman used no technique; she got well, it appears, through her deep-seated resolve, and that was good enough. This case, too, I must call a quantum event. because’ of the fundamen.al transformation that went deeper than organs, tissues, cells, or Lien DNA, directly to the source. of the body’s existence in time and space. Both of my patients one with positive thoughts, the other with negative managed to dip into the? realm, and from there they dictated their own reality.

As mysterious as these tow cases are, are they really examples of quantum events? A physicist could object that we are just making metaphors here, that the hidden world of c1ollentar)’ particles and fundamental forces explored by quantum physics is very different from the mind’s hidden world. Yet, one can argue that the inconceivable region from which we fetch the thought of a rose is the san,,! as that from which a photon emerges or the cosmos. Intelligence, we will discover, has many quantum properties. To make this clear, we start with the familiar text article scheme that arranges die body vertically as a
systems, organs, tissues, and cells

In this picture, each level of the body is logically related to the next as long as you remain above the line, the processes that appear as life Unfolds happen in a definite sequence. This is exhibited by a fetus in the womb: a baby begins as a speck of DNA sitting in the middle of one fertilized egg cell; over time, that cell multiplies until a ball of cells is formed, large enough to begin to sort itself out into the of tissues and eventually organs, such as the hurt, spinal cord, and so on then the entire nervous system, digestive system, respiratory system, and so on emerge; and finally, at the moment of birth, the trillions of cells in the newborn are precisely coordinated to sustain the life of .the whole organism without the mother’s help.

But if DNA is the bottom rung of this neat stepladder, what makes DNA unfold in the first place’ Why does it initially divide on the second day after conception and begin to make a nervous system on day eighteen’ As with all quantum events, something inexplicable happens beneath the surface to form the all-knowing intelligence of DNA. The point is not that DNA is too complex to understand, being a super genius molecule; what makes DNA mysterious is that it lives right at the point of transformation, just like the quantum. Its whole life is spent creating more life, which we have defined as “intelligence tied up in chemicals.” DNA is constantly transferring messages from the quantum world to ours, tying new bits of intelligence to new bits of matter.

Sitting by itself in the middle of every cell, completely offstage, DNA manages to choreograph all that happens onstage. It can spin our parts of itself to travel through the bloodstream as neuropeptides, hormones, and enzymes, while at the same time attaching other bits of itself to the cell wall as receptors, setting up antennae to listen for answers to a flood of questions. How does DNA manage to be the question, the answer, and the silent observer of the whole process at the same time? The answer is not at the level of matter. Molecular biologists long ago broke DNA down into its finer components, bur the whole operation still remains above the line in the Newtonian world:

As we saw before, DNA is not made out of anything special. Its strands of genetic material can be subdivided into simpler molecules like sugars and amines, and these into atoms of carbon, hydrogen, oxygen, and so on. When it is not tied into DNA, a hydrogen or carbon atom doesn’t have anything like timing built into it. In billions of other combinations, hydrogen and carbon simply exist; yet in DNA, they contribute to a mastery over time, an ability to produce something new every day, which lasts, in a human being, more than seventy years every stage of life .develops according to DNA’s timetable. (In a bristlecone pine, DNA is timed for more than two thousand years.)

No matter how closely you look, the ground for the stepladder is not very firm. When you get beyond atoms and start subdividing DNA into electrons, protons, and smaller particles, a quantum event must take place Otherwise, you are left in the embarrassing position of claiming that life is made out of nothingness empty space’ devoid of matter and energy which is all you get if you divide ’solid particles beyond a certain point.

At the quantum level, matter and energy come into being out of something that is neither matter nor energy. Physicists sometimes refer to this primordial state as a “singularity,” an abstract construct that is not limited in time and space but is a compression of all the expanded dimensions of the universe. In the Big Bang, the whole universe jumped out of a singularity so it is theorized which we can think of by analogy as a point smaller than the smallest thing in existence. Yet, that stupendous event of creation happens on another scale every time you think the word rose.

There is no piece of matter existing in a definite place that holds this word for you it springs into existence from a region that simply knows how to organize matter and intelligence, mind and form. The atoms in your brain come and go, but the word rose does not disappear. Now we are at a very exciting point: The singularity is quite explorable today: it did nor exist before the Big Bang, since it is outside rime and space; therefore, it must be here now in fact it is everywhere and has no confines in past, present, or future. Quantum physics uses mammoth particle accelerators and other arcane equipment to wrest from the? zone even one minute glimpse of this hidden world. The track of a new elementary particle whining by for a millionth of a second is a major finding because it means that the unknown
zone has been
reached and a bit of its reality brought into ours. Can it really be that we are doing the same thing just-by thinking, feeling dreaming, and wishing?

What would the quantum level inside US be like? It would simply be the logical extension of something we are very familiar with by now, the neuropeptide. The neuropepride’s great ability is that it can respond with lightning speed to the mind’s commands. It does this, I believe, by sitting on the borderline of the ‘1nanOlm zone. Science has already discovered that hundred of neuropeptides exist and are manufactured all over the body. It is just another step to find that every one of our cells can make every one of these substances. If that rums out to be true, then the whole body is a “thinking body,” the creation and expression of intelligence. Here is another diagram that sketches the situation:

We already know that intelligence can take the from of a thought or a molecule, this is represented in the diagram by having “mind” and “body” as the two choices that intelligence can make. The two are always matched to each other even when they appear to be separate. To coordinate them, I have inserted a quantum level, called the “quantum mechanical body.” This is not a physical artifact but a layer of intelligence, the layer where the body as a whole is organized and correlated. This is where the know-how comes from that makes molecules “smart” instead of inert.

We should not assume that thoughts turn into messenger chemicals one at a time. It is well known that in many ways all the billions of bits of DNA in our systems act like one big DNA molecule, as when the incredibly complex development of a fetus is coordinated in the mother’s womb from the first day to the ninth month, all the DNA in an unborn child acts as one. The same holds true for us today. Perhaps quantum events are not exclusively “out there” in space, but “in here” as well. Do we have “black holes” into which matter and energy disappear forever? Yes we call it forgetting. Do we speed up time and slow it down, as
space traveler does in the event that his rocket can accelerate to near the speed of light? Yes again, for a writer can think up in an instant a story that may take hours of normal time to set down on paper; conversely, you can spend half an hour trying to retrieve someone’s first name, which comes instantly once you find the timeless zone, called memory, from which it must be retrieved.

Whenever any mental event needs to find a physical counterpart, it works through the quantum mechanical’ human body. That is the secret of how the two universes of mind and matter associate with-each other without mistakes. No matter how different they appear, mind and body are both soaked through with intelligence. Science tends to be skeptical in the face of any claim that intelligence is at work in nature this is a strange historical anomaly, since every generation before us has accepted without question some kind of universal order). However, if there is nothing outside ordinary reality to hold things and events together, then one is led to a set of impossibilities.

We can see this in the law of gravity. Common sense says that two objects separated by empty space should have no connection with each other; in the jargon of physics, they occupy their own “local reality.” But the Earth revolves around the sun, held in its orbit by gravity, even though the two bodies are separated by a void of 93 million miles.

When he discovered this violation of local reality, Newton was shocked and refused to speculate on how it happens. Since then, local reality has taken one beating after another. Light, radio waves, lasers, and all other electromagnetic forces travel through empty space; matter and antimatter seem to exist in coordinated universes that have no physical contact; subatomic particles have spins that are matched to one another, and it doesn’t matter how far apart in time and space the particles are their spins can be matched at opposite’ ends of the universe.

What this implies is that the commonsense idea of local reality is true only at a certain level. The whole of reality, as explained by quantum physics, lies deeper. A famous mathematical formula, known as, Bell’s theorem (after its author, the Irish physicist John Bell), holds that the reality of the universe must be nonlocal; in other words, all objects and events in the cosmos are inter-connected with one another and respond to one another’s changes of state. Bell’s theorem was formulated in ‘1964, but decades earlier, the great English astronomer Sir Arthur Eddington had anticipated inter-connectedness by saying, “When the electron vibrates, the universe shakes.” Physicists now accept inter-connectedness as a ruling ‘principle, along with many forms of symmetry that extend across the universe for example, it is theorized that every black hole may be matched up somewhere with a corresponding “white hole,” though .none has actually been observed.

What kind of explanation would satisfy Bell’s requirement for a totally inter-connected, nonlocal reality? It would have to be a quantum explanation, because if gravity is present everywhere at the same time, if black holes know what white holes are doing, and if a change of spin in one particle causes an equal but opposite change instantly in its partner somewhere in outer space, it is obvious that the information going from one place to the other is traveling faster than the speed of light. This is not permitted in ordinary reality, either by Newton or Einstein.

Contemporary theorists such as British physicist, David Bohm, who
has worked extensively with the implications of Bell’s theorem, have had to suppose that there is an “invisible field” that holds all of reality together, a field that possesses the property of knowing what is happening everywhere at once. (The word invisible here means not just invisible to the eye but undetectable by any measuring instrument.) Without going deeper into these speculations, you can see that the invisible field sounds very much like ·the underlying intelligence in DNA, and both behave very much like the mind. The mind has the property of holding all our ideas in place, in a silent reservoir. so to speak, where they are precisely organized into concepts and categories.

Without calling it “thinking,” we may be watching nature think through many different channels, of which our minds are one of the most privileged, because the mind can create its quantum reality and experience it at the same time. Witnessing a quantum even in the field of light waves may seem completely objective, but what if quantum reality was just as present in our own thoughts, emotions, and desires? Eddington once flatly stated his belief as a physicist that “the stuff of the world is mind-stuff.” So the quantum mechanical body, as a formation of intelligence, has a plausible’ place in nonlocal reality.

The beauty of such a simple picture is that intelligence is simple; the complications arise when one tries to track down the incredibly complex machinery of the mind-body system. The brain-wave patterns of a psychotic and a poet look the same on a roll of EEG paper as it comes off the electroencephalograph, no matter how sophisticated the analysis. Thinking about the thousands of hours it would take to scientifically describe the chemical consequences of one cell’s daily life, a neuroscientist friend of mine remarked, “You have to conclude that nature is intelligent because it’s too complicated to be called anything else.”

He could just as easily have said “too simple.” A human brain that changes its thoughts into thousands of chemicals every second is, after all, not so much complicated as inconceivable. In ancient India, it was supposed that intelligence existed everywhere; it was called Brahman, from the Sanskrit word for “big,” and was Just like an invisible field. A saying from thousands of years ago holds that a man who has not found Brahman is like a thirsty fish who has not found water.

Our whole physiology can be transformed as quickly as a neuropeptide, which is an integral part of the quantum mechanical body. Because we can change like quicksilver, the flowing quality of life is natural to us. The material body is a river of atoms, the mind is a river of thought, and what holds them together is a river of intelligence.

It may seem that the quantum mechanical body is involved only in life or-death situations, but that isn’t so. We live in it, casually and without thinking, just as we live in the body as a whole. I have a patient who glimpsed this fact while sitting on the grass eating French bread and listening to Mozart. She had been a frustrating case for more than two years. She suffered from a combination of nagging symptoms, including irritable bowel, headaches, fatigue, insomnia, and depression, that humbled every attempt m cure her. None of these conditions was fatal, but they made her life miserable nonetheless. Conventional treatment with anti-depressants and tranquilizers had done her little good; neither had anything I did using Ayurveda.

Then one day she went m Tanglewood, the summer home of the Boston Symphony and an idyllic place to have a picnic. She spread out a checkered cloth, lay in the sun listening m music, and peacefully ate her lunch. These things made her very happy, and that night she slept soundly for the first time in years. However, she was so used to being sick that this new event did not register on her. Another year of misery passed, until it was time for her to go m Tanglewood again; and the same thing happened all her symptoms disappreared tor the day, and she slept beautifully that night.

This time it registered. She came to see me jubilantly waving a sheaf of reprints [mm medical journals on the SAD syndrome. The initials stand’ for “seasonal affective disorder,” referring to a condition in which patients become seriously depressed every winter without apparent cause. Now’ we know that the cause has to do with the pineal organ, deep inside the skull; this small, flat, oval endocrine gland, although surrounded by brain matter, responds to changes in sunlight, being the source of the ‘ “third eye” that everyone wants to look through

In one New Age (some lower animals such as the lamprey do possess a literal third .eye). In certain people, insufficient exposure to sunlight in the winter throws off their pineal secretions; the gland starts to produce too much of a hormone called melatonin, giving rise to depression.

“See,” she said, “I’ve had SAD all along, and by sitting in the sun, I’ve got a normal pineal gland again.” ”I’m sorry,” I said, “but that disorder occurs in winter.” Her face, started to fall, and I quickly added, “You’ve put your finger. on something important, though. Now we. have a deficiency we can treat.” “What’s that’” she asked. “Picnic deficiency,” I said. For, the first time since I’d known her, she flashed me a genuine smile.

Her self-treatment continues to work. She regularly escapes the gray confines of her office building to sit in the sun at lunch, talk to friends, and listen to lots of Mozart, This may not sound like advanced medicine, and in a sense it isn’t, but the reason it works is that we need Nature to free up our nature. We are surrounded by the best of all healing influences fresh air, sunlight, and beauty. In India, the’ Hippocrates of Ayurveda, a great physician and sage named Charaka, prescribed some sunlight for all diseases, along with a walk in the early morning, and his advice will never grow stale.

If I find a green meadow splashed with daisies and sit down beside a clear-running brook, I have found medicine. It soothes my hurts as well as when I sat in my mother’s lap in infancy, because the Earth really is my mother, and the green meadow is her lap. You and I are strangers, bur the internal rhythm of our bodies listens to the same ocean tides that cradled us in a time beyond memory.

Nature is man’s healer, because Nature is man. When Ayurveda says that the sun is our right eye and the moon our left eye we mustn’t sneer. By bathing us in the moon, the sun, and the sea, Nature fashioned the bodies we inhabit, These were the ingredients that provided us each with our piece of Nature a/shelter, life-support system, intimate companion, and home for seven decades or more.

The discovery of the quantum realm opened a way to follow the influence of the sun, moon, and sea down deeper into ourselves. I am taking you there only in the hope that there is even more healing to be found there. We already know that a human fetus develops by remembering and imitating ·the shapes of fish, amphibians, and early mammals. Quantum discoveries enable us to go into our very atoms and remember the early universe itself. Aeons ago, light and heat came into being in · the universe, to last for 20 billion years; yet, every human being strikes the spark again, lighting the fire that kindles life. In Vedic India, the same sacred fire that was in the hearth shared the name Agni with the’ digestive fire in the belly and. the solar fire in the sky.

Sir Arthur Eddington once affirmed that there were two realities that had to be known on their own terms, one of which was trivial, the other all-important. The trivial one was the mechanistic reality investigated by science; the all-important one was the human reality of ordinary experience. In the scientific reality, Eddington said, Earth is a speck of matter whirling around a mediocre scar, both of them cast adrift among billions of more important stellar objects. But in the human reality, Earth remains the center of the universe, because the life it harbors is the’ only important thing that exists, at least for us. The most poignant expression of this idea came to me from a patient who had many health problems, including cancer. To regain her perspective, she wrote “down certain important experiences from her past. One of these occurred when she was a girl of 16; she entitled it, “But How Can I Be the Moon? Age 16:”

Lying alone In the pasture, dark except for the magnetic full moon. There is an overwhelming sense of quietness. My being is part of the earth and part’ of the pure white light of (he moon at the same time. Nothing else is significant. For a second I wonder, “Am I dead?” It isn’t important-I am spending an hour in God’s hands. and it will become part of me. A surprising number of people have had such experiences, which Eddington called “the mystic contact with the earth.” My patient later slipped away from her experience, gradually becoming used to the grind of work and family worries that disconnects all of us from Nature; in her case, the accumulated stress led to frequent sickness. (She wryly titled her later life, “Going Against Nature This Is Adulthood”’).

What is so unusual is that when she stopped going against Nature, the old feeling of contact came back with undiminished freshness. In her late twenties she visited the Pacific shore and wrote this: For about two hours on the beach alone, I was with God again. I was the surf, its sound and strength. I was the sand, warm, vibrating, alive. I was the breeze, soft and free. I was the sky, endless and pure. I felt only great love. I was more than my body and knew it. This moment was absolutely cleansing and beautiful.

What she expresses I also believe as a doctor. The healing mechanism inside us perfectly matches the one outside. The human body does not
look like the green meadow, but its breezes, its laughing water, sunlight, and earth were merely transformed into us, not forgotten. (There is good reason for all the ancient ·medicines to say that man is made of earth, air, fire, and water.) Because the body is intelligent, it knows this
fact, and when it returns home to Nature, it feels free. With overflowing joy it knows its mother. That feeling of freedom and joy is vital it allows inner and outer nature to blend. The same is true of the quantum mechanical body; it is just a doorway back to Nature. One does not even need to explain it, except for the sad fact that the intellect, going against Nature, has done such a good job of blocking the door.

There is a lot more to say about the quantum mechanical body. I can think of nothing we need to know more about. Today, medicine .wants to make the leap beyond its present dilemmas, but the wanting has turned into waiting. A fellow student from my medical-school days in

New Delhi has risen meteorically as a research physician in the United States, becoming a professor at Harvard Medical School before he turned 45. Recently we sat after dinner in a Boston restaurant and he predicted the future. “All the top researchers met quietly in Washington,” he said glumly, “and we agreed that by the year 2010, no major cancer would be cured, and there would be no breakthrough in understanding AIDS.”

This gloomy prognostication must be avoided at all Costs. It may be impeccable science, but it makes no sense from the quantum perspective. We are all expert navigators in the realm of? zone, where science gropes with one small light. Doesn’t this suggest a solution? The mysterious breakdowns of the body’s intelligence that occur in cancer and AIDS may all be traceable to a single distortion a wrong detour into the hidden regions of DNA’s intelligence. To see how the mind-body problem can be solved, we need to look more closely at these detours and their invisible origin.

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Ghosts Of Memory

October 24, 2009 Uncategorized

Recently a young woman in her late twenties, a part-time model, came to my office in Boston. After years of hiding the fact that she had an eating disorder, her family had finally persuaded her to seek treatment. Since adolescence she had been obsessed with her figure, and over time this concern had become more and more abnormal until it blossomed into a double sickness, anorexia nervosa and bulimia.

Looking at this attractive, bright woman, who to all appearances was normal, was not lulled into thinking that her problem was easy. Despite extensive research and publicity in recent years, both anorexia and bulimia remain highly puzzling. Why should young women, many of them well educated and from high-income backgrounds, nurture an uncontrollable obsession with diet and weight? Anorexics develop a fear of food and a horror at the act of eating. Confined to a rigidly ritualized pattern of behavior that leads them to voluntary starvation, they will deny that they are too thin, even to the point of death.

The companion disease, bulimia, can be separate from anorexia or can coexist with it, as in this woman's case. In bulimia, the horror of food rakes a weird turn in the form of bingeing. The secret food binges that a bulimic goes on are often enormous anywhere from 2,000 to 50,000 calories at a sitting (2,000 calories is enough food to sustain a vigorous 150-pound person for a day). This huge amount of food is then vomited back up, causing tremendous stress to the digestive system and the body a whole.

This particular woman's disorder had advanced to the point where she was vomiting every day in order to maintain the normal bur still low weight needed for her work. The very sight of a dessert, she told me, caused her to break out in a cold sweat and sent her heart racing. She was extremely intelligent and listened closely when I said that at the root of her disorder 'Was a mistake in her self-image. Because our society is. obsessed with the ideal of thinness, many women try to live up to an ' inner image of their bodies that is simply not right for their physical makeup. In her case, however, the image was not saying, "I have to be thin." It was saying, "I can never be thin enough."

To explain this paradoxical illness, one has to drop the distinction between mind and body and think of one system, the "body-mind." This is because an eating disorder is a holistic disease, the cruel opposite of holistic health. In anorexics, the distorted idea, must be thinner," rakes over the body-mind like a malevolent and elusive phantom. Even alder long hospitalization and exhaustive psychiatric treatment, the patient rarely eats like a normal person. A normal person would have to snuggle to starve himself once the body went past a certain point of deprivation, its hunger signals would take precedence over everything else in the body-mind, until the desire for food became overpowering. For someone with anorexia, the same thing happens bit in reverse the compulsion to avoid eating is all but irresistible.

As I was talking about this, the young woman looked at me sorrowfully and whispered, "So there really are such things as ghosts, aren't I was startled, and after a moment I answered, "It's true, bur this ghost can be exorcised." What we were talking about is a ghost of memory, a memory picked up and stored in the body. Memory sounds very abstract, while food is very concrete. But the memory is far more real in this case. Whether a person is compulsively too thin or too fat does not depend primarily on how much food he takes in. This is true for conditions that are less bizarre than anorexia. For centuries, obesity has been seen as a flaw in character, which religious ages called the sin of gluttony. The implication was that if fat people were just strong enough and used a little self-discipline, they could be as thin as the rest of us simply by eating less.

Now it is generally recognized that for the chronically obese, diets do not solve the problem (just as , at the opposite extreme, filling an anorexic with food does not solve that problem), because the brain of a fat person is actually sending out overpowering signals for too much food How these messages are triggered and how to turn them around are open questions. Unless some degree of control is gained at a very deep level, obese people can spend their whole lives forcing themselves to diet, a self-defeating tactic that only makes the mental distortion worse. The loss of 10 pounds is registered in their brains as a famine, and the next time food is offered, the brain will not stop until 15 pounds is put back on, adding an extra 5 as a safety margin against the next famine. Obese people have been known to gain weight on diets where no extra calories are offered beyond the bare minimum to sustain basal metabolism. The reason for this is that the brain can actually alter the metabolism in such a way that the calories are scored as fat instead of being burned up as fuel.

No one knows why the intellect is so powerless to change these distortions in self-image. The ghost gets stronger the more you fight it. Although anorexics will persistently deny that they have a problem, once the doctor pierces this defense, it is clear that a profound split in the body-mind is involved, with one part of the system struggling to maintain rationality while another sends up wildly irrational impulses.

Out conversation had been rather eerily reasonable until she suddenly snapped at me, "Do you really think you can talk me out of this? I already understand the whole thing perfectly, you know, and it hasn't done me a damn bit of good. Leave me alone. This is how I have to eat." She glared at me with unconcealed hostility. "Tell me," she demanded, "how many people do you cure of smoking by talking to them? They know what Nicole does and the danger of lung cancer and all that. It doesn't do them any good to talk, and you won't do me any good, either."

I sat back, feeling the cold blasts of despair and the hot blasts of hatred in what she had said. How horrible co have co live with both , in a weird, poisonous tangle. "The real question isn't whether I can help you, is it?" I pointed out after she calmed down. "It's whether you can help yourself." She started to soften just a little, and I added gently, "You know, you're not hurting me by not eating. You're not hurting anyone real at all, but someone who is an image. It is all inside you, and that is the part that is so cough, both for you as a person and for me your doctor." This story does not have an immediate happy ending. Certainly my patient was right about the futility of talking about her disease. She remains a very hostile, confused person, and my best hope is that joining a peer group with other anorexics and bulimics will help, To get her to exorcise the ghost of memory, she will have to teach the level where the ghost lives. Until the ghost is gone, patients like her do not feel that they have a disease they are their disease.

I mean this quite literally. What happens to you when you see a snake and jump out of its way? The frightened thought, Look out, a snake! comes to mind at exactly the same instant as adrenaline makes you jump. Usually the thought and the action are so closely tied together that the conscious thought doesn't even have time to say its words you just see the snake and you jump. So there is no space where you can drive in a wedge between the two. In the case of an anorexic, the mere sight of food sets up a wave of revulsion. Perhaps the sight and smell of a fresh loaf of bread sends the thought, Ugh, I can't eat this, while at the same time the stomach turns, the salivary glands dry up, and the whole digestive tract is alerted not to function.

Naturally ,his is a twisted reaction, but the thought and the reaction come packaged together, and there is no place to drive in a wedge between them. What is at work here is something we can call an "impulse of intelligence," which means a thought and a molecule tied together, like a two-sided coin. Once the impulse Starts to rise, there is no turning it back. The thought is the molecule; the molecule is the thought. At the time it takes place, an impulse of intelligence constitutes the patient's whole inner reality. When an anorexic is repelled by food, her reaction is all there is (at least for that instant)–she is her disease at the moment. The same holds true for the obese person trying to resist food, the smoker trying to resist another cigarette, and so on. You cannot change a thought after you have had it the entire inner struggle of such patients is totally futile. But there is another component to an impulse of intelligence besides the thought and the molecule. The third component is silence; this is the unseen component. Like all of us, the anorexic must fetch thoughts from the region that lies deeper than thought, and it is there that a cure might be found.

The anorexic's dreaded realization, I am my disease, may be true, but it is not the final truth. If the anorexic could transcend her compulsions, looking on them without involvement, her disease would end. Becoming a silent witness would be enough to disentangle her from the ghost. Archimedes said that if he had a lever long enough and a place to stand on, he could move the Earth presumably, he would have to stand in outer space. The anorexic needs just such a place; unfortunately, a human being is confined to inner space. No one has a spare nervous system hanging in the closet in case his primary one gets strange ideas. Sadly but inevitably, there is no place outside to stand on. Without realizing it, we count very heavily on the fact that our thoughts will trigger the right chemicals in our bodies; the mind and its messenger molecules are automatically and perfectly matched. But this process can break down, and then the resulting confusion is like running two programs on the same com purer when the input is scrambled, it is no wonder that the printout, your body, becomes garbled. For example, one of the most ambiguous drugs ever devised is Valium.

Valium belongs to a class of chemicals called benzodiazepines, which are used as both tranquilizers and sleeping pills. These substances were greeted in their day as revolutionary. Their predecessors, the barbiturates, had many notorious drawbacks: they were highly addictive; they induced poor-quality sleep because they blocked REM, or dream sleep; and overdoses could prove fatal. Valium and its relatives, on the other hand, produced better sleep with less hangover, were much harder to overdose on, and at first seemed nonaddicrive. At the height of its immense popularity, Valium was said to account for one-quarter of all new prescriptions written in America.

Now it is known that Valium is itself addictive, that it produces sleep irregularities of its own (interfering with the third and fourth stages of deep, dreamless sleep), and that serious withdrawal symptoms occur after prolonged use. If you look at the level of the receptors on the cell wall, none of this is surprising, because Valium acts by outcompeting the body's own neurochemicals and taking over their receptor sites. This kind of interference would perhaps be advantageous if Valium compared only with the neuropeprides responsible for causing the feelings of anxiety (called, octadecaneuropeprides). Bur the calming effect of the drug does not come by itself; Valium confuses the nervous system as a whole. Moreover, it was recently discovered that the monocytes of the immune system also are attracted to Valium. So when a doctor· gives what he thinks is a sleeping pill or a tranquilizer, be is affecting the immune system at the same time, adding more confusion at the level of the receptors.

No one knows if this has caused any harm, largely because the finding about the immune system is coo new. In all likelihood, we will discover that nature has already provided our bodies with an exact internal analogue to Valium, which means that we are clumsily reproducing something that already exists in nearly perfect form. lf I ask myself whether I like the idea of plugging the same chemical into my immune cells every day, in the indiscriminate fashion that Valium was doled out to millions of patients, primarily women, for thirty years, the answer is obvious.

The immune cells have a reason for each receptor; they use to think, act, perceive, and respond in precise ways. A person uses the same two eyes to view the whole world; a cell, however, has a different eye for each thing it needs to see. In other words, a constantly filled receptor renders the cell blind to one specific thing. At a time when the incidence of many cancers, such as breast cancer, is still rising, sending unknown messages into the immune system seems very risky.

Currently there is a "chemical revolution" under way in the treatment of mental disease, and it seems as miraculous as Valium did thirty years ago. Doctors now widely give their mental patients mind-altering, or psychotropic, drugs to clear up the overt symptoms of their sickness. mainly depression, mania, and hallucinations. The symptoms are often relieved, sometimes quite dramatically and suddenly, although malty patients cannot tolerate the mental numbness and fatigue that are common side effects (not that the side effects are simple: certain antidepressants can make the patient's depression worse for the first few weds, or swing it in the opposite direction until it rums into wild mania). Critics of drug therapies call them "chemical lobotomies' and charge that they strip the patient of his human dignity. Doubtless there are many abuses, particularly in large, understaffed public hospitals fur the insane. It takes very careful fine-tuning to stabilize the correct dosage of any psychotropic drug, and horror stories abound of depressed patients who reacted so badly to their medication that they committed suicide rather than endure the cure. Still, the success  in this field implies that drugs will be used to cure schizophrenia and depression altogether, if not today, then in the future.

A "cured" schizophrenic does not yet exist through chemical means. This is because there is more to being normal than not having hallucinations. Once you suppress a schizophrenic's bizarre visions or the strange voices he hears in his head, you do not find a normal person facing you, but a shell. Altering the chemical level of dopamine, even if it could be done a hundred times better than it is done today, will not lead to a cure. The reason is contained in the article learned from the neurotransmitters themselves: for every chemical breakthrough, there is also a chemical barrier.

The good news about neurotransmitters is that they are material. A thought, whether sane or mad, is hard to grasp because it is so intangible; it is not something you can touch or feel. The neurotransmitters, however, are certainly tangible, although they are extremely tiny and often short-lived. It is the neurotransmitter's role to match up with a thought. To do that, its molecules must be just as flexible as thoughts, just as fleeting, elusive, changeable, and faint. Such flexibility is a kind of miracle bur also a curse, in that it throws up a barrier that is almost impossible to pass. No man-made drug can duplicate this flexibility, either now or in the foreseeable future. No drug actually pairs up with a thought. This is apparent just by looking at the structure of the receptor.

Receptors are not fixed: they have been accurately described as looking like lily pads that have floated up from the depth of the cell. Like lily pads, their roots sink downward, reaching the cell's nucleus, where the DNA sits. DNA deals in many, many kinds of messages, potentially an infinite number. Therefore, it makes new receptors and floats them up to the cell wall constantly. There is no fixed number of receptors, no fixed arrangement on the cell wall, and probably no limit to what they are tuned in too A cell wall can be as barren of lily pads as a pond in winter, or as crammed as one in full Bower in June. The only thing constant about a receptor is its unpredictability. Searchers recently discovered, for example, that a neurotransmitter called imipramine is produced abnormally in the brains of depressed people. While looking for the distribution of imipramine receptors, they were starred to find them not just on the brain cells but on skin cells. Why should the skin create receptors for a "mental molecule"? What did these skin receptors have to do with depression?

One plausible answer is that a depressed person is depressed everywhere he has a sad brain, sad skin, sad liver, and so on. (Likewise, researchers have examined patients who complain of feeling jittery all the time and discovered abnormally high levels of two chemicals, epinephrine and norepinephrine, in their brains and adrenal glands. However, high concentrations were then found in their blood platelets, meaning that they had " jittery blood cells," too.) It has been frustrating for doctors to realize how complex the whole business is becoming. Hopes for a quick cure of schizophrenia, depression, alcoholism, drug addiction, and other disorders were dashed in the mid-1 970s, just a few years after the original endorphins had been isolated in 1973 Now the chemical barrier is stronger than ever, as the true flexibility of the messenger molecules is being divined.

Thinking about this problem, I have to ask myself a deeper question: Can a drug really exorcise the ghost of memory? My medical experience says no I have seen too many depressed patients who were " cured" by drugs and yet who still radiate a feeling of hollow sickness. Instead of trusting drugs, one needs to find out how the patient's sick memory got into his chemical system to begin with. For it is absolutely clear chat the nonmaterial memory is there. It may be caking a ride on a molecule, but its life does not depend on that. The following case serves as an example.

Water grew up on the streets of south Boston in the late 1960s; he felt the edge of hatred that greeted black people who moved into that neighborhood. To escape this and the poverty that had dogged him ail his life, Walter joined the Army at 18. Within six months he found himself in Vietnam. He fought in combat and survived, but when he bounced back onto the street again two years later, he was hooked on heroin, which many soldiers used to make the war less traumatic. Unlike most soldiers, Walter had no reason to quit when he got home. Eventually the police caught him, and by order of the court he came under my care at the V.A. hospital for his addiction.

Our main focus was simply to detoxify Walter. In the normal course of things, he would have passed through the revolving door and back Out onto the street. But while he was staying in the hospital I began visiting with him. It was clear that he was an exceptional person. Despite his desperation, he did not seem eaten up by inner violence, and he was courageously willing to fight his habit. Walter made friends with me. He also made quick progress medically, and a year after detox he was still holding a steady job and talking eagerly about the normal life he longed for and loved.

Then a strange incident occurred. One day Walter's car broke down, forcing him to take the subway to work, which he hadn't done in several months. He got on the train to Dorchester, an old, clattery line with screeching rails. He hated the noise and couldn't manage to ignore it. The fan was broken, and it was July. Within a few minutes of being shut up in the hot, stifling compartment, he found the train intolerable. He went from feeling uneasy to agitated to extremely agitated, and by the time he got off he was in a completely wild, irrational state. Nothing he could do would make his agitation go away By the time I saw him, two days later, Walter was completely hooked on heroin again, and this time he had hardly any will to recover.

What happened to this man? A chemical explanation fur the train incident is not sufficient. I keep thinking of him wearing his pinstriped business suit, confidently outfitted fur a new life, but then having to step onto the same train that he had ridden when he was troubled and addicted. In some treacherous he of memory. lane, the past came bock, and with it came his craving. Where did the craving hide our for a year before it returned In some way that medicine is just beginning to unravel, a cell's memory is able to outlive the cell itself.

At any point in the body-mind, two things come together a bit of information and a bit of matter. Of the two, the information has a longer life span than the solid matter it is matched with. As the atoms of carbon, oxygen, hydrogen, and nitrogen swirl through our DNA, like birds of passage that alight only to migrate on, the bit of matter changes, yet there is always a structure waiting for the next atoms. In fact, DNA never budges so much as a thousandth of a millimeter in its precise structure, because the genomes the bits of information in DNA -remember where everything goes, all 3 billion of them. This fact makes us realize that memory must be more permanent than matter. What is a cell, then? It is a memory that has built some matter around itself, forming a specific pattern. Your body is Just the place your memory calls home.

This conclusion is difficult to argue with, in light of all that we now know about forms of chemical intelligence, bur medicine stubbornly resists these implications. For instance, it is generally believed that people who are addicted to alcohol, cigarettes, or drugs have a "chemical addiction," meaning that their cells are hooked on nicotine, alcohol, heroin, et cetera. But if you look at the level of the body's chemistry, you find that heroin or nicotine fits into the same receptors on the cell walls that everyone has. An addict does not have receptors that exhibit abnormal cravings.

By analogy, a fat man's stomach lining isn't addicted to food it Just accepts what is given to it. The truth seems to be that the cell's memory for the addictive substance is what is hooked, and it keeps creating distorted cells that reflect its weakness. In other words, an addiction is a distorted memory. It is just our material bias that keeps looking to the cell. (These pernicious memories may be inherited, since addiction runs in families, but even if there is a specific addiction gene, one is forced to consider the nonmaterial conditions that caused the DNA to express the gene. Your ears are formed because a gene encodes them, but the reason the ear was developed in the first place, millions of years ago, was certainly nonmaterial some organism stoned to respond to sound.

If you take an addict, detoxify his body, and keep him away from alcohol or drugs for several years, all the old cells that used to be "chemically addicted" are totally gone. Yet the memory persists, and if you give it a chance, the memory will latch onto the addictive substance :o nce again. A good friend of mine, a cardiologist from Colombia, gave up smoking fifteen years ago. This spring he went back home and happened to go to a movie, a rare event in his life. He is an extraordinarily busy man, even for a than doctor, and had not seen a movie since he , could remember. There was ,an intermission in this particular show, and when he walked into the lobby he was seized by an almost uncontrolled the urge to smoke,

"You see, when I was a teenager in Bogota," he told me, "we used to smoke in the lobby between movies. All I did was step back into that scene, and the urge to smoke came back in a flash. I found myself in front of the cigarette machine fumbling for change, and only by clutching myself inside and repeating, 'This is crazy, you're a cardiologist,' was I able to resist." Even so, he had to rush out of the theater and now wonders ruefully how the movie ended. What makes any addiction so frightening is that the brain's receptors are always willing to cooperate with the mind's instructions. Think back to the stress reaction where a car backfires and adrenaline is released into your bloodstream. We noted that as part of the overall reaction,. the stomach and intestines Stop digesting food, As long as the stress reaction is temporary, this is a completely normal and correct thing for the body to do, and it happens automatically.

However, if you choose to stay in an environment where there is constant stress, the time must come when your body wants to return to digesting food. Then a deep conflict will arise, because the stress react ion will still be saying "no" to the stomach while another part of the brain (probably the hypothalamus) is saying "yes." The resulting turm6il ties the stomach in knots and churns up the intestines. These organs begin to lose their natural rhythm, and if you do not give them a chance to return to it, they will become victims of wrong memory, just as surely as an addict does. The stomach will start pouring out gastric juice at the wrong tipples, the colon will go into spasms, and the smooth linkage between the whole gastrointestinal system will collapse. Hence the burning ulcers and chronic irritated colon experienced by many people under high stress.

In the case of the addict, one of the reactions that is blocked by drugs is the ability to think rationally and perceive clearly. As long as his receptors are full, the addict will feel euphoric and his perceptions will be a woozy blur, a condition that may be pleasant in the short run but devastating over the long term without clear perception, the brain cannot issue the most basic. instructions for thinking, eating, working, · relating to other people, and so on. All of life requires clear thinking, clear thinking requires a best of different neurotransmitters, yet the addict has seized on only a few and clings to them desperately. Likewise, a strictly physical explanation for cancer is not convincing. It must be tied in to a distortion that is more abstract; perhaps a distorted memory can occur at the cellular level. Lee us say that a doctor takes a patient's X ray and discovers a malignant tumor, then a year later another X ray 15 taken and the same rumor shows up. The doctor is in fact nor accurate in calling this the same cancer, because the cells that showed up the year before have been entirely replaced . What be is .really seeing is the result of a memory that bas persisted, reincarnating again and again In a new tumor. Cancer is not so much a wild, runaway cell as .the distorted blueprint of that cell, a set of wrong instructions that turns normal cellular behavior into the suicidal mania of cancer When we are fortunate, the body deals with this situation from a primary level. The DNA senses any deviation in memory, including incipient tumors, and quickly eliminates it.

As yet we do not know how to wipe out cancerous memories at the cellular level, because we cannot penetrate the cell wall to "talk" to the . DNA. It is known, however, that a key step is taken when the immune system secretes certain anti-cancer agents called interleukins, a class of proteins that resemble hormones. Our immune cells produce interleukins in many situations cuts, bruises, infections, internal tissue damage, and allergies all call them forth. (The name "interleukin" was chosen because researchers originally discovered that these chemicals send signals between leukocytes, or white cells.)

As they naturally occur, interleukins exist in minute quantity; therefore, they are prohibitively expensive to duplicate commercially. Despite this obstacle, researchers have. recently extracted large amounts of interleukin-2 (IL-2) and transfused it into about 450 patients with advanced skin and kidney cancers (the current price runs as high as $80,000 for a single course of treatment). Some patients, from 5 percent to 10 percent, have had dramatic regressions of their tumors via this therapy, at the cost of severe side effects, which have killed several people. The question of the IL-2's long-term influence on the rest of the body remains unanswered.

Despite their drawbacks, interleukins are on the verge of becoming the next promising cancer cure, as interferon, a close chemical relation, was the cure of the 1970s. Already, reams of genetic engineers are racing to figure out how to manufacture interleukins on a marketable scale. With a sinking feeling, one senses that another false hope is being born. Why is the promise never fulfilled? Medicine knows hundreds of facts about interleukins, such as that "the alpha and beta strains of interleukin- l are only 26 percent homologous at the amino-acid level of their genes"; or that both bind to receptors "with high affinity in the 10-10 molar range." When one penetrates the jargon, these are not insignificant facts.

Yet they say literally nothing about interleukin's intelligence, which is the salient point. If interleukins "know" when and white to fight cancer, then it is not their molecules that should interest us, but something invisible the cell's ability to recognize that a cancerous memory is present and needs to be eradicated. This cannot be injected into the body. The body's war against cancer pits intelligence against intelligence. The physical manifestations interfer6n, interleukin, hormones, peptides, et cetera may be thought of as weapons if you like, but they must first be aimed. In the deepest sense, that is why I have no faith in the "magic bullet" approach.

Penicillin was an effective bullet because one's aim did not have to be at .all accurate; once an antibiotic in the bloodstream, it aromatically attacks the cell walls of bacteria and destroys them. Similarly, early chemotherapy for cancer was a crude bullet, no different from the chemical warfare of World War (In fact, the most toxic drugs used against cancer, called alkylation agents, originated with nitrogen mustard, the infamous mustard gas that so terrified soldiers in that war.) Later classes of chemotherapy, such as the various adrenal hormones and estrogen, derived from the body itself, and therefore their aim was less approximate; but now we see that this advance in fact may be the last gasp of the magic-bullet theory.

At a certain point, the chemicals you want to use are so precise that their action is effective only within the narrowest possible limits. If you aim a hormone, you have to hit one receptor, not Just the huge, broad avenues of the bloodstream where penicillin goes. If the receptor you want to hit is involved in a complex process, as the ones for interleukins are, then no aim may ever be accurate enough, for the life and death of the cell involves the precise attunement of every chemical it contains. By analogy, if you mistune one string inside a piano, you have thrown everything out of tune; a piano sonata will never be right if even note is wrong.

I do not mean to make this sound like the logic of doom. Millions of patients have been successfully treated with cancer drugs. The toxicity of chemotherapy has been steadily reduced, and in many cases the dreaded side effects' that have given the treatment its bad reputation are actually fairly mild; particularly considering the risk of leaving cancer untreated. But it still remains true that without very early detection, cancer is incurable. If a patient comes to me with lung cancer, even early detection is no help. I can give him radiation and call it a therapy, but in 95 percent of the cases it is little more than a short reprieve perhaps he and I go through with it just to fend off the despair of having no treatment at all. Other common cancers, such as melanomas, belong in this category.

We desperately need a medicine without bullets. If you look at interleukins free of a material bias, their most important attributes are invisible. Interleukins are being produced by the immune cell's DNA in exact dosages, combinations, and timing, all of which ace more important than the molecule itself. A white cell engulfing an invader, such as a bacterium or cancer cell, looks deceptively simple under the microscope, like a drop of amber surrounding a fly. In actuality, there is no more intricate process in the human body. An interleukin arrives on the scene at a precisely determined point in a most exacting maneuver. We may call this the "hunt for cancer," but much of the immune process is highly abstract. It is conducted almost entirely by the exchange of information. Hitting the target is one of the more minor parts of the campaign.

Before a macrophage, or immune cell, ever secretes any anti-cancer agent, the immune system goes through many other steps. It must first detect that a problem exists and identify it exactly; a cancer cell is not a virus, and neither one is a bacterium. Using a class of message carriers called helper T cells, the body notifies the rest of the immune system to become activated and starts to produce natural killer cells. To make sure that the killers do not destroy the wrong thing, the body hangs a chemical nametag on the macrophages inscribed with the enemy's identify, which they can show to other cells the meet. This is just the barest outline of the immune system's initial sequence of action, which bas many branches, overlapping, and unexplained convolutions.

Having just fathomed the full intricacy of the immune system in the last five years, researchers like to compare it to the brain in complexity. Like the brain, the immune system bas a phenomenal capacity for absorbing new information, learning and memorizing the identity of any new disease organism, and sorting out billions of bits of knowledge. We could just as easily say that the brain and the immune system ate not like each other they are each other, because they operate within the same chemical network.

The only difference between an immune cell and a brain cell is that their DNA has selected to emphasize certain aspects of its total knowledge and suppress others. Interleukin comes very close in structure to being a neuropeptide (the research literature calls it a "hormone like polypeptide"). This means that when our emotions join up with molecules, like riders on a horse, the mounts they choose are almost identical to interleukin. For all intents and purposes, to feel happy and to fight cancer are much the same thing at the molecular level. We could call both of them healing messages.

It is false even to divide cells into senders and receivers of such messages; for although certain immune cells secrete interleukins as part of their specific role, virtually every cell in the body can receive them; implying an ability to produce them as well. Perhaps this "silent" ability is activated in spontaneous remissions. Or are there levels of thought that fight the ghosts of memory hand to hand, and the physical molecules we see are just so many fired shells littering the battlefield? For this last possibility to be true, the mind would have to be directly aware that a cancerous memory is endangering us. Certainly the addict and the anorexic know that the ghost is there. And I have already mentioned certain tumors, such as tumor of the pancreas, that begin to make the patient moody and depressed long before the doctor can physically detect the malignancy. This early warning still depends on the actual presence of a cancer cell. However, that does not exclude a warning that is earlier still.

To find out where it might come from, we will have to go deeper into the whole issue of how intelligence and matter are paired. It is imperative to do this, I believe, before the magic-bullet theory collapses. Interleukin is not a bullet but a speck of life on the move, with intelligence the invisible rider. Life itself is intelligence riding everywhere on chemicals. We mustn't make the mistake of thinking that the rider and the horse are the same. Intelligence is free to go where it likes, even where molecules cannot.

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Messengers From Inner Space

October 24, 2009 Uncategorized

To climb to Machu Picchu, the fortress city of the Incas, is a formidable task. One crosses a sixteen-thousand-foot pass in the high Andes, where the oxygen is already low enough to cause giddiness, and once the city is in sight above the clouds, its walls are reached by three thousand Stone steps. This was the last stronghold captured by Pizarro when he conquered Peru in 1532. One is astonished to think that. foot-runners connected Machu Picchu with every village along the two thousand miles of the Incan empire. They were swift· messengers of almost inhuman endurance. They ran barefoot, covering immense distances every day at .times the equivalent of two or three Olympic marathons. Some of their trails began at the height of a mountain peak in the Colorado Rockies and ascended more than a mile higher.

It must have been these runners, the eyes and ears of the emperor Atahualpa, who warned him of the approaching Spanish. By treachery, Pizarro co1lected a fortune in ransom when he kidnapped (and later . murdered) Atahualpa. One hopes the legends are true which say that the most priceless Incan gold was secreted away in time. (Pizarro, who was unusually greedy, even for a conquistador, was himself murdered by jealous rivals in 1541.)

If you think of the human brain as the fortress at Machu Picchu, then it too must have runners to carry its commands to the farthest outposts of its empire in this case, the big toe. The physical routes are certainly visible the central nervous system runs down the spinal column, branching out on either side at each vertebra in the backbone; these major nerves then branch into millions of tinier pathways that communicate to every region of the body. The early anatomists saw the major nerves in the sixteenth century, but the nervous system kept a secret. Who were the runners that took the messages to and from the brain?

Many people still think that the nerves work electrically, like .a telegraph system, because until fifteen years ago, that is what medical texts contended. However, in the 1970s, a series of important discoveries began, centering on a new class of minute chemicals called neurotransmitters. As their name implies, these chemicals transmit nerve impulses; they act in our bodies as "communicator molecules," whereby the neurons of the brain can talk to the rest of the body. Neurotransmitters are the runners that race to and from the brain, telling every organ inside us of our emotions, desires, memories, intuitions, and dreams. None of these events are confined to the brain alone.

Likewise, none or them are strictly mental, since they can be coded into chemical messages. Neurotransmitters touch the life of every cell. Where ever a thought wants to go, these chemicals must go too, and without them, no thoughts can exist. To think is to practice brain chemistry, promoting a cascade of responses throughout the body. We have already seen that intelligence, as know-how, pervades the physiology'-now it has acquired a material basis.

That gives away the plot of this article, but with none of the drama. In truth, no other recent event in biomedicine has been as revolutionary as these discoveries. The arrival of neurotransmitters on the scene makes the interaction of mind and matter far more mobile and flowing than ever before far closer to the model of the river. They also help fill the gap that apparently separates mind and body, one of the deepest mysteries that man has faced since he began to consider what he is.

At first, around 1973, it seemed that only two neurotransmitters were needed, one to activate a distant cell, such as a muscle, and the other to slow down the activity. Two brain chemicals, acetylcholine and nor epinephrine, do just that; they are the "go" and "slow down" signals of the nervous system. They were considered revolutionary at the time, because they proved that the impulse sent from one nerve cell to the next was not electrical but chemical in nature. All at once, the accepted notion of tiny sparks jumping from neuron to neuron was rendered obsolete. But the new chemical model at first continued to preserve the basic theory that only two signals were necessary. Man-made computers operate using just this kind of binary switch, and apparently so did the brain.

Then, as molecular biologists around the world began to investigate more deeply, numerous new neurotransmitters cropped up, each with at different molecular structure and apparently a different message to deliver. Structurally, many of them were related, being built up as peptides, complex chains of amino acids of the same kind as those which appear in the proteins that make up every cell, including brain cells. A great many riddles began to be solved, directly or indirectly, as these discoveries emerged. If you take a sleeping cat, remove a tiny portion of its spinal fluid, and inject it into a cat that is awake, the second cat will immediately fall asleep. This is because a eats brain puts its body to sleep chemically, with its own internal sleeping potion. In order for the' animal to wake up again, the opposite chemical, a wake-up signal, must be injected into the spinal column.

In humans, where the same chemical mechanisms operate, the body is awakened in the morning not by a rude internal alarm but by a series of timed signals, at first mild, then progressively stronger, that lift us from deep sleep by stages. The whole process involves a gradual transition, in four or five waves, from the biochemistry of sleep to the biochemistry of wakefulness. If this process is interrupted, you do not come as fully awake as you should the biochemistry of two distinct phases has been mixed. That is why patents of newborns, having to get up several times during the night, feel that they ate never quite normal during the day. Alarm clocks also jolt us out of out natural wake-up patterns, giving rise to grogginess that may persist all day, until the next round of sleeping and waking readjusts the mind-body chemistry.

He is a related example. All camels exhibit an unusual tolerance for high levels of pain they can calmly chew on thorns while at the same time being beaten with a stick by an irate camel driver. Curious researchers examined camels' brain cells and found that they produce large quantities of a specific biochemical that, if injected into other animals, causes them to ignore pain, too. Sleep and pain tolerance, it is now known, thus depend on precise chemical messengers produced in the brain.

One by one, various other functions that were once "all in your head" have been connected to specific neurotransmitters. Schizophrenics suffering acutely from hallucinations and psychotic thoughts often improve dramatically if put on a kidney dialysis machine, which filters impurities from the blood. As we saw, brain researchers have established that a neurotransmitter called dopamine exists in abnormally high levels in the brains of schizophrenics. Current chemical treatment of the disorder entails using psycho-active drugs that suppress dopamine; perhaps the dialysis machine is actually removing it, or a related by-product, from the bloodstream.

By the mid-1980s, barely ten years after the original breakthrough, more than fifty such neurotransmitters and neuropeptides were known. All fifty can be manufactured on one side of the synapses between our neurons, and once they cross the synapses, all fifty can be received by the receptor sites on the other side. This implies an incredible flexibility to communicate from cell to cell. The individual neuron was now seen to be a producer of messages that did not just say "yes" or. "no," as a computer does. The brain's vocabulary is far larger, encompassing thou- sands of combinations of separate signals, with no end in sight, since new neurotransmitters continue to be discovered at a fast rate.

What kind of messages do nerve cells exchange with one another? The answer is tantalizing, for certain segments of our chemical vocabulary seem to be Just as specific as ordinary speech, while others are highly ambiguous, Our tolerance for pain, like the camel's, depends on the class of biochemicals discovered in the 1970s called endorphins and en-kephalins, which act as the body's natural painkillers. The word endorphin means "internal morphine," and enkephalin means "inside the brain." And that is their story: they are like a version of morphine produced by the brain itself.

This 'hitherto unknown ability, to make internal opiates proved very exciting. It was already suspected' that the body must be able to regulate the sensation of pain. Although insistent, pain does not always register on our awareness. Strong emotions, for example, can override pain signals from the body, as when a mother rushes to save her child from a burning house or a wounded soldier fights on, ignoring the pain of his injuries. Under more ordinary circumstances, all of us to some extent can take our attention away from a minor pain we don't notice a sore throat, for instance, if we are talking to someone with intense interest. Despite this common experience of having the pain threshold rise and fall, no mechanism had ever accounted for it. Now medicine could explain it by using these internal painkillers, the endorphins and enkephalins, which every neuron, in the body is able to produce at will.

Very quickly the general public was told that the brain produces narcotics up to two hundred times stronger than anything you can buy on the street, with the added boon that our own painkillers seemed to benonaddictive. Perhaps in the future a physician would anesthetize his patients by stimulating some region in their brains, giving Western medicine a scientific form of Chinese acupuncture.

Morphine and endorphins both block pain by filling a certain receptor on the neuron and preventing other chemicals that carry the message of pain from coming in. Without these chemicals, there can be no sensation of pain, no matter how much physical provocation is present, Using this model, a molecule of endorphin is like a specific word, the word painkiller. One can imagine that whenever the word pain comes to the brain's attention, it has the option of sending painkiller back as its answer. Unfortunately, this simple picture was clouded over by later research.

It was found that levels of endorphins in the body do not correspond on a one-to-one basis with how much pain is being felt. This can be proved with placebos, or dummy drugs. Patients who' are in pain can' often be relieved by receiving a placebo, usually a coated sugar pill, which they are told is a powerful painkiller. Not everyone will respond to this, but generally between 30 percent and 60 percent will report that their pain went away. This result, called the placebo effect, has been noted for centuries, but it is highly unpredictable. The doctor cannot tell in advance which patients will benefit or to what extent.

Why should a totally inert sugar pill relieve pain in the first place, even the stabbing pain of peptic ulcers or traumatic surgery? Endorphins, it was now discovered, must hold the answer. A drug called naloxone acts as a chemical antagonist to morphine, meaning that it has the ability to knock morphine molecules out of a receptor site. When naloxone is administered on top of a painkiller, the sensation of pain instantly floods back. As it turns out, the same thing will happen with the placebo. The patients whose pain went away from the sugar pill reported that it returned again after they took naloxone. This implied that endorphins and morphine must basically be the same drug, the difference being that one is manufactured by the body and the other by the opium poppy.

But once again, it was only a certain percentage of patients who showed this result. Naloxone made the pain return in full force for certain patients; for others, the placebo effect still worked totally; and for still others, only a little of the pain came back. Researchers found themselves in a state of renewed confusion, where they remain today. Endorphins are certainly internal painkillers, but uncovering these new molecules was not the whole answer.

Pain studies have now shown that morphine is not chemically identical to endorphins, that endorphins interact in a more complex way than narcotic drugs, and that any form of treatment for pain relief-morphine, endorphins, acupuncture, or hypnosis-is highly variable. In Its effectiveness, It was also discovered that endorphins cannot be made into satisfactory pharmaceuticals: our internal painkillers are Just as addictive as heroin if given by injection. Soon, the same frustrating complications that scientists ran up against with the endorphins and enkephalins spread to all the other neurotransmitters. It turns out that a neuron does not simply catch a signal from a neighboring nerve cell and pass it along untouched to the next synapse. That is only one of its choices.

Although no one can describe exactly how neurons receive their chemical messages or how they transport them down their own axons, or trunks, it is known that the process must be very flexible. The nerve cell can change the message en route, turning the chemical it received at point A into a different one at point B. The receptor sites on the ends of nerve cells can also modify themselves to receive different types of messages; the sending station on the other side of the synapse is equally versatile.

For our purposes, this confusion is actually a highly encouraging state of affairs, because it proves that the body cannot be understood without the missing ingredient of intelligence, The physical makeup of endorphins, or any other neurochemical, is not nearly as important as their know-how how they choose their sites, what triggers them to act, how they "talk" to the rest of the body in precise coordination, and so on. Even in the midst of a genuine chemical revolution, mind is superior to matter. In fact, it now appears that the molecular Structure of any neurotransmitter is completely secondary to the brain's ability to employ it. It came' as a tremendous surprise to cell biologists that, as far as molecules go, neurotransmitters are nothing specia1. All of the protein in our bodies is built up from chains of twenty basic amino acids, and these chain's can be further arranged into longer strands cal1ed peptides Neuropeptides have their own signature, making them distinct from the other peptide chains in the body, but the same factory, our DNA, makes all of them. DNA is the Source fur all the proteins that repair cells, build new ones, replace missing or defective pieces of the genetic code, heal Cuts and bruises, and so forth.

Without bothering to invent a new class of chemicals, the DNA has figured out another use for its familiar raw materials, the amines, amino acids, and peptides. Once again, it is just the ability to make these different products that is crucial. There is nothing special about the molecules themselves, even though their discovery by a molecular biologist may be special to science. " Where does the ability to make the neurotransmitters come from, then? Perhaps we should look to the contribution made by the mind. After all, it is not really ' the adrenaline molecule that makes a mother rush into a burning building to save her child or an endorphin molecule that protects her from feeling the 8ames. Love makes her rush in, and single-minded determination protects her from pain. It just happens that these' attributes of her mind have round a chemical pathway that the brain can follow to talk to the body.

Now we have arrived at the bean of the matter. Mind by any definition is nonmaterial, yet it has devised a way to work in partnership with these complicated communicator molecules. Their association is so close, as we have seen, that mind cannot be projected into the body without such chemicals. Yet these chemicals are not mind. Or are they? The whole paradoxical situation was wittily summarized several years ago when the eminent English neurologist and Nobel. Prize winner Sir John Eccles was asked to address a conference of parapsychologists, who were discussing the usual topics of LSP, telepathy, and psycho kinesis the ability to move physical objects with the mind.

If you want to see real psycho kinesis, he told his audience, the consider the feats of mind over- matter performed in the brain. It is quite astonishing that with every thought, the mind manages to move the atoms of hydrogen, carbon, oxygen, and the other particles in the brain's cells. It would appear that nothing is further apart than an insubstantial thought and the solid gray matter of the brain. The whole trick is somehow done without any apparent link.

The mystery of mind-aver-matter has not been explained by biology, which prefers to push on to more and more complicated chemical structures operating at finer and finer levels of the physiology. It is still obvious that no one is ever going to find a particle, however minute, that . nature has labeled "intelligence." This is all the more apparent when we realize that all the matter in our bodies, large or small, has been designed with intelligence as a built-in feature. DNA itself, although acknowledged as the chemical mastermind of the body, is made up of I essentially the same basic building blocks as the neurotransmitters it manufactures and regulates. DNA is like a brick .factory that is also made out of bricks. (The great Hungarian mathematician John von Neumann, besides being a founder of the modem computer, was interested in robots of all types. He once invented, on paper, a truly ingenious machine, a robot that could build robots identical to itself in other words, a self-reproducing machine. Our DNA has accomplished the same thing on a grand scale, since the human body is nothing more than variants of DNA built by DN, A.)

You may find it easy to think of DNA, with its billions of genetic bits, as an intelligent molecule; certainly' it must be smarter than a simple molecule like sugar. How smart can sugar be? But DNA is really just strings of sugar, amines, and other simple components. If these are not "smart" to begin with, then DNA couldn't become smart just by , putting more of them together. Following this line of reasoning, why isn't the carbon or hydrogen atom in the sugar also smart' Perhaps it is. As we shall see, if intelligence is present in the body, it has to come from somewhere, and that somewhere may be everywhere. If we follow the next step of the neurotransmitter story, we find out- selves faced with another quantum leap in complications, but surprisingly, the relation between mind and matter actually begins to clear up

The areas .of the brain that mediate .our emotions the amygdale and the hypothalamus, which is also known as "the brain's brain" were both found to be particularly rich in all the substances in the neurotransmitter group, This implied that where thinking processes ate abundant (meaning that many neurons are tightly clustered), so will be the chemicals associated with thinking. At this point there was still a rather well-defined division between chemicals that jumped the gap between brain cells and those that traveled from the brain down the bloodstream, (In my field, endocrinology, .one .of the defining qualities .of a hormone is that it Boats through the blood, a process that is generally much slower than the transmission speed of a nerve cell, which has been clocked at 225 miles per hour; a signal sent from head to toe takes less than 1I50th .of a second,)

Just when science thought it could isolate brain chemicals and categorize their sites, the body cropped up with its .own complication. Researchers at the National Institute .of Mental Health found receptors in equal abundance at .other sites outside the brain. Starting in the early 1980s, receptors for neurotransmitters and neuropeptides were discovered on cells in the immune system called monocytes. "Brain" receptors .on white cells in the blood? it would be hard to exaggerate the significance of this discovery. In the past, it was thought that the central nervous system alone relayed messages to the body, rather like a complicated telephone system connecting the brain to all the .organs it wanted to "talk" co. In this scheme, the neurons function like telephone lines conveying the brain's signals that is their unique function, shared by no other system in the physiology.

Now it was seen that the brain does not just send impulses traveling in straight lines down the axons, or trunks, .of the neurons; it freely circulates intelligence throughout the body's entire inner space. Unlike the neurons, which are fixed in place along the nervous system, the monocytes of the immune system travel through the bloodstream, giving them free access to every other cell in the body. Outfitted with a vocabulary to mirror the nervous system's in its complexity, the immune system apparently sends and receives messages that are just as diverse. In fact, if being happy, sad, thoughtful, excited, and so on all require the production of neuropeptides and neurotransmitters in our brain cells, then the immune cells must also be happy, sad, thoughtful, excited indeed, they must be able to express the full range of "words" that neurons do. Monocytes can be thought of in effect as circulating neurons.

With this one discovery, the concept of the intelligent cell took on full -fledged reality. One kind of localized intelligence was already well known, that possessed by the DNA in every cell. Since Watson and Crick mapped the structure of DNA in the early 1950s, investigation had proved that this remarkable, almost infinitely complex molecule • encoded all the information necessary to create and sustain human life. But the intelligence of genes was seen primarily as fixed, because DNA itself is the stables chemical in the body, and thanks to that stability, each of us is able to inhere genetic traits from our parents blue eyes, curly hair, facial patterns, et cetera and preserve them intact to pass on to our children.

The know-how carried by the neurotransmitters and neuropeptides represented something else altogether: the winged, fleeting, sentient intelligence of the mind. The wonder is that these "intelligent" chemicals are not only made by the brain, whose function is to think, but by the immune system, whose primary role is to protect us from disease. From the· standpoint of a brain chemist, this sudden expansion of messenger molecules adds a new order of complexity to his work. But for us; the discovery of "floating" intelligence confirms the model of the body as a river. We needed a material basis for claiming that intelligence flows all through us, and now we have it.

Anyone can see that his mind is filled with a bewildering flood of impressions that are far too amorphous to pin down. To describe it, psychology is reduced to equally amorphous terms like the famous phrase stream of consciousness. Today, as if to fill that stream with water you can actually see and touch, brain researchers have found cascades of brain chemicals. But unlike a stream, these cascades have no banks; they flow anywhere and everywhere. They never cease this flow, either, for the smallest fraction of a second. A brain scientist in effect Stops time to examine a cascade's components. The chemicals he wants to find are extremely minute it took three hundred thousand sheep brains to yield a single milligram of the molecule the brain uses to stimulate the thyroid.

Nor are the cell receptors easy to grasp. They constantly dance on the surface of the cell walls and change their shape to receive new messages; anyone cell may contain hundreds or even thousands of sites, only one or two of which can be analyzed at a time. Science learned more about brain chemistry in the last fifteen years than it knew in all of previous history, but we are all still like foreigners trying to learn English from scraps of paper found in the street.

No one has yet been able to grasp how the cascade of chemicals exactly patterns itself to do all the things a mind can do. Memory, recollection, dreaming, and all the other everyday activities of the mind remain a profound mystery as far as their physical mechanics is concerned. But now we know that the mind and body are like parallel universes. Anything that happens in the mental universe must leave tracks in the physical one.

Recently brain researchers have found a way to photograph. a thought's tracks in 3-D, like a hologram. The procedure, known as PET (positron-emission tomography), is done by injecting the bloodstream with glucose whose carbon molecules have been tagged with radioisotopes. Glucose is the brain's sole food, which it uses much faster than do ordinary tissues. Therefore, when the injected glucose reaches the brain, its marker molecules of carbon can be picked out as the brain uses them, and thus pictured in three dimensions on a monitor, much the same way a CAT scan is produced. Watching these marker molecules shift around while the brain thinks, scientists saw that each distinct event in the universe of mind such as a sensation of pain or a strong memory triggers a new chemical pattern in the brain, not just at a single site but at several. The image looks different for every thought, and if one could extend the portrait to be full length, there is no doubt that the whole body changes at the same time, thanks to the cascades of neurotransmitters and related messenger molecules.

As you see it right now, your body is the physical picture, in 3-D, of what you are thinking. This remarkable fact escapes our notice for several reasons. One is that the physical outline of the body does not change drastically with every thought. Even so, the whole body quite obviously projects thoughts. We literally read other people's minds from the constant play of their facial expressions; without marking it, we also register the thousand fold gestures of body language as a sign of their moods and intentions toward us. Films made by sleep laboratories disclose that we change position dozens of times during the night, obeying commands from the brain that we are unconscious of.

Secondly, we don't see our bodies as projected thoughts because many physical changes that thinking causes are unnoticeable. They involve minute alterations of cell chemistry, body temperature, electrical charge, blood pressure, and so on, which do not register on our focus of attention. You can be assured, however, that the body is fluid enough to mirror any mental event. Nothing can move without moving the whole. The latest discoveries in neurobiology build an even stronger case for the parallel universes of mind and body. When researchers looked further, beyond the nervous system and the immune system, they began to discover the same neuropeptides and receptors for them in other organs, such as the intestines, kidneys, stomach, and heart. There is every expectation of finding them elsewhere, too. This means that your kidneys can "think," in the sense that they can produce the identical neuropeptides found in the brain. Their receptor sires are not simply sticky patches. They are questions waiting for answers, framed in the language of the chemical universe. It is very likely that if we had the whole dictionary and not just our few scraps, we would find that every cell speaks as fluently as we do.

Inside us, the questions and answers go on forever. Just by itself, a single gland like the thyroid has so much to say to the brain, to its fellow endocrine glared, and though them to all the body, that its cascade of conversation influences dozens of vital functions, such as growth, metabolic rate, and much more. How fast you think, how tall you are, and the dimensions of your eyes, for example, all depend in part on advice from the thyroid. We can safely conclude, then, that mind is not confined to the brain by some neat division set up for our own convenience. Mind is projected everywhere in inner space.

One of the most forward-looking and accomplished researchers in the field of brain chemistry, Dr. Candace Pert, director of the brain biochemistry division at the National Institute of Mental Health, has pointed out that it is quite arbitrary to say that a biochemical like DNA or a neurotransmitter belongs to the body rather than the mind. DNA is almost as much sheer knowledge as it is matter. Dr. Pert refers to the entire mind-body system as a "network of information," shifting the emphasis .away from the gross level of matter toward the subtler level of knowledge.

Is there really any reason to keep mind and body apart at all? In her own writings, Pert prefers to use one term for both-body-mind. If this word sticks it will clearly indicate that a wall has come crashing down. Pert does not have all of medical science behind her yet, but that may change very quickly. It is becoming clearer every day that the mind and body are amazingly alike. Insulin, a hormone always identified with the pancreas, is now known to be produced by the brain also, Just as brain chemicals like transferor and CCK are produced by the stomach. This shows that our neat division of the body into nervous system, endocrine system, digestive system, and so on is only partially right and may soon be outmoded. It has now been absolutely proved that the same petrochemicals influence the whole body-mind. Everything is intercom necked at the level of the neuropeptide; therefore, to separate these areas is simply bad science.

A body that can "think" is far different from the one medicine now treats. For one thing, it knows what is happening to it, not just though the brain, but everywhere there is a receptor for messenger molecules, which means on every cell. This explains a great deal about drugs and their side effects that had not been known. Some drugs have a bewildering number of side effects. If I consult my physician's which comprehensively lists the medications that a doctor can prescribe, I can find article after article under the listing for conic steroids. The most familiar conic steroid (or just steroid) is cortisone, but the whole family, is widely prescribed to treat burns, allergies, arthritis, postoperative inflammation, and dozens of other conditions.

If you didn't know about receptor sites, steroids would appear highly peculiar. Let us say that I prescribe steroids to a woman who is suffering from a difficult case of arthritis. The steroids would bring down the inflammation in her joints dramatically, but then a host of ,strange things might happen. She could begin to complain of being fatigued and depressed. Abnormal fatty deposits might begin to show under her skin, and her blood vessels could become so brittle that she would develop large bruises that are very slow to heal. What could link these entirely divergent symptoms?

The answer lies at the level of the receptors. Conic steroids replace some of the secretions of the adrenal cortex, a yellowish pad on the top of the adrenal glands. At the same time, they suppress the other adrenal hormones, as well as secretions from the pituitary gland, which is located in the brain. As soon as it is given, the steroid rushes in and floods all the receptors throughout the body that are "listening" for a certain message. When a receptor becomes filled, what follows is not a simple action. The cell can interpret the adrenal "message" in many ways, 'depending on how long the site stays filled. In this case, the receptor stays filled indefinitely. (The fact that other messages are not being received important, as is the loss of innumerable connections with the other endocrine glands.)

The cell can exhibit extreme reactions from filling one receptor. By analogy, look at a moth hanging under the eaves on a summer night. In a male moth, the fuzzy antennae on its head are actually receptor sites that have extended outside the body. As the sun sets, the moth waits for, a signal from a female moth in his vicinity, who is emitting a special molecule called a pheromone. Moths are tiny creatures, and the number of pheromones they can send through the air is infinitesimal compared to the total volume of air and its immense freight of pollen; dust, water; and other pheromones being secreted by animals of every kind, including man. One would hardly suspect that two moths can communicate over any sizable, distance.

But when a single pheromone molecule lands on the male's antenna, his behavior is transformed. He swiftly homes in on the female, begins an elaborate courtship ritual in the air, and proceeds with the act of mating. Biologically speaking, the only thing that censer this complicated behavior is one molecule.

When I give steroids to an arthritis patient, trillions of molecules and receptor sites are involved. That is why the blood vessels, skin, brain, fat cells, and so on all exhibit their different responses. If I go to my desk reference, the long-term consequences of staying on steroids include diabetes, osteoporosis, suppression of the immune system (making a person more susceptible to infections and cancer), peptic ulcers, internal bleeding, elevated cholesterol, and much more. One might even include death among these side effects, because raking steroids for a long period causes the adrenal cortex to shrivel (an example of how an organ will atrophy if not used). If the steroid is withdrawn too quickly, the adrenal gland does not have time to regenerate. The patient is left with inadequate defenses against stress, which adrenal hormones help to buffer. He can go to the dentist to have a wisdom tooth extracted, a stress that is usually well within the normal limits, but deprived of adrenal hormones, he can go into shock. A tooth extraction could even kill him.

Take all of these details together, and what you see is that steroids can cause literally anything to happen. They may be the immediate cause or just the first domino the distinction makes little difference to the patient. To her, there is no difference between the osteoporosis caused-by steroids and the "real thing." The same holds for depression, diabetes, or death. A single messenger has caused them all. In truth there is no such thing as a single messenger each one is a strand in the body's web of intelligence. Touch one strand, and the whole web trembles. I realize that this makes drugs look much more dangerous than we had thought, even in an era that is obsessed with cataloging medical disasters.

We are used to a more limited idea of what a side effect is a touch of the bitter with the sweet, like the thorn that comes with the rose or the hangover with the bottle of wine. Instead, a side effect balloons out into anything the body ' can think of. Generally we are protected from serious harm because the body reacts along certain narrow lines. A patient who takes an aspirin might experience bleeding in his stomach lining but not a heart arrack. However, every cell in the body has a wide latitude for action .it is a conscious being who understands the world around it. The side effects in my desk reference are just the one that have been observed so far.

I recently read a story of an internist ' who was baffled when one of his patients, a man in his late seventies, suddenly began to act paranoid. The man was obsessed by the idea that robbers were going to break into his house, and he bought a gun to keep. under his pillow. One night he terrified his wife by leaping out of bed at three in the morning, running downstairs with his pistol, and searching wildly for the intruders he thought were behind every chair. Knowing that he was hallucinating dangerously, the wife rushed him to the interties. The patient had no prior history of mental illness and was on no medications other than digitalis, which he took to stabilize his heart rhythm. Considering the patient's age, a diagnosis of Alzheimer's disease seemed imminent. However, the internist consulted a neurologist to read the patient's CAT scan. Nothing abnormal appeared on it, but the neurologist said, "I bet this man is hallucinating from the digitalis." In thirty years of practice, the internist, who is also a professor of medicine in New York City, had never seen this side effect, although he had heard of it, barely.

He reduced the digitalis, and within ten days the patient returned to normal. It seems quite freakish that a highly specific heart medication should lead co insanity. If this patient had .hallucinated a few decades ago, when the desk reference did not list such a bizarre side effect, no doctor would have believed it; today, the internist believed it only after an extensive battery of tests ruled out everything else.

What this case teaches is that you can never tell what the body is thinking, or where. It is entirely possible that the man's heart went insane, in the sense that it coupled the first domino and triggered the onset of his paranoia. The brain and the heart share many of the same receptor sites; more important, they share the same DNA, which implies that a heart cell can behave like a brain cell, a liver cell, or any other kind of cell. After open-heart surgery, patients sometimes have psychotic breaks and begin hallucinating. Flat on their backs, groggy from deprivation of oxygen to the brain, and locked into the blank sterility of an intensive care unit, they suddenly think that little green men are marching up and down the sheets such is the accepted explanation for their episodes. Could it be that in fact it is the heart that is hallucinating here? Simply the trauma of the surgery could make the heart think that reality has run wild, and that is why it tells the brain.

The discovery of neurotransmitters, ides, and messenger molecules of all kinds has vastly extended our concept of intelligence. But if every cell has an endless number of it can send and receive, it is also clear that only a small fraction are activated at one time. Who or what controls the That rums our to be an explosive question. In a chemistry lab, reactions will run automatically as soon as the experiment starts; it is just a matter of mixing one chemical with another. Yet, someone has to take the chemicals off the shelf to begin with.

Medicine has traditionally preferred to ignore this fact as it applies to the human body. Now we see that with thousands of chemicals on its shelf, a cell has not only co choose some, mix them together, and analyze the results. It has co make the chemicals in the first place, finding thousands of ways to create new molecules out of basically a handful of elements carbon, hydrogen, oxygen, and nitrogen. To do that requires a mind. So, by following the story of neuropeptides, we have ultimately arrived at a dramatic shift in worldview. For the first .time in the history of science; mind has a visible scaffold to stand upon. Before this, science declared that we are physical machines that have somehow learned to think. Now it dawns that we are. thought that have learned to create a physical machine;

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The Sculpture or The River?

October 23, 2009 Uncategorized

Counting the number of cells in the human body is no easier than counting the number of people in the world, but the accepted estimate is 50 trillion, or about 10,000 times the Earth’s present population. Isolated and placed under a microscope, the various kinds of cells heart, liver, brain, kidney, et cetera look rater alike to the untrained eye. A cell is basically a bag, enclosed by an outer membrane, the cell wall, and filled with a mixture of water and swirling chemicals. At the center of all but the red blood cells is a core, the nucleus, which safeguards the tightly twisted coils of DNA. If you hold a speck of liver tissue on your fingertip, it looks like calf’ liver; you would be hard-pressed to discern that it is specifically human. Even a skilled geneticist would detect only a 2 percent difference between our DNA and a gorilla’s. Of the liver cell’s many functions, over five hundred at latest ‘count, you would not have a clue simply by looking at it.

As clouded as the mind-body issue has become, one thing is indisputable: somehow human cells have evolved to a state of formidable intelligence. At anyone time, the number of activities being coordinated in
our bodies is quite literally infinite. Like the Earth’s ecosystems, our physiology appears to operate in separate compartments that in fact are invisibly connected: we eat, breathe, talk, think, digest our food, fight off infections, purity our blood of toxins, renew our cells, discard wastes, vote for Republicans, and much more besides. Each of these activities weaves its way into the fabric of the whole. (Our ecology is more planet like than most people realize. Creatures roam our surface, as unmindful of our hugeness as we are of their minuteness. Colonies of mires, for
example, spend their entire life cycle in our eyelashes.). Within the body’s vast array, the functions of any single cell such as one of the 15 billion neurons in the brain fill a good-sized medical text. The volumes devoted to anyone system of the body, such as the immune system or the nervous ’system, take up several shelves in a medical library.

The healing mechanism resides somewhere in this overall complexity, bur it is elusive. There is no one organ of healing. How does the body know what to do when it is damaged, then? Medicine has no simple answer. Anyone of the processes involved in healing a superficial cut the clotting of the blood, for example is incredibly complex, so much so that if the mechanism fails, as it does with hemophiliacs, advanced scientific medicine is at a loss to duplicate the impaired function. A doctor can prescribe drugs that replace the missing clotting factor in the blood, but these are temporary, artificial, and have numerous undesirable side effects. The body’s perfect timing will be absent, as well as the superb coordination of a dozen related processes. By comparison, a manmade drug is a stranger in a land where everyone else is blood kin. · It can never share the knowledge that everyone else was born with. The body, we must admit, has a mind of its own. Once we understand this mysterious aspect of our basic nature, then the miraculous nature of curing cancer should disappear. Everyone’s body knows how to heal cut, yet apparently only a few people have bodies that know how to cure cancer.

Every doctor realizes that it is nature who cures disease, a statement first written by Hippocrates two thousand years ago. What is the difference, then, between nature’s ordinary form of healing and unusual or “miraculous” healing? Perhaps the difference is small and exists only in our heads. If you are peeling potatoes and cut your finger with a slip of’ the knife, the cur heals by itself, and obviously you are not wonder-struck, because the process · of healing the clotting of the blood to close the wound, the formation of a scab, and the regeneration of new skin and blood vessels seems altogether normal.

Yet, we should be aware that this feeling of normalcy is not the same as knowing what healing is or how to control it. It is sobering to consider how much of the knowledge in medical articles pertains not to life but to death. By performing autopsies on cadavers, examining tissue slides under a microscope, and analyzing blood, urine, and other isolated by-products of the body, the majority of medical knowledge has been obtained. True, patients are examined when they are alive, and tests can be run on many isolated functions in their bodies. But the knowledge so acquired is rudimentary compared to the volumes of super-sophisticated data devoted to death. The poet Wordsworth wrote this memorably terse line: “We murder to dissect.” No truer statement has ever been made about the limitations of medical research.

The first thing that is killed in the laboratory is the delicate web of intelligence that binds the body together. When a blood cell rushes to a wound site and begins to form a clot, it has not traveled there at random. It actually knows where to go and what to do when it gets there, as surely as a paramedic in fact, more surely, since it gets completely spontaneously and without guesswork. Even if we break down its know!- edge into finer and liner bits, looking for the secret in some minute hormone or messenger enzyme, we will not find a protein strand labeled “intelligence,” and yet there .is no doubt that intelligence is at work. Part of this intelligence devotes itself to healing, and it seems to be a very powerful force. Every fatal disease has its mysterious survivors, not just cancer. Although I know of no spontaneous cutes of AIDS, there are long-term survivors those who remain alive after five years whose immune systems have somehow defended themselves against a disease that under normal conditions is totally devastating Researchers tend to approach such extraordinary physiologies as biochemical freaks of nature.

By taking samples of their blood and isolating any unusual components that can be detected in the immune cells, molecular biologists hope to discover the unknown ingredient that ·is protecting these people. If that can be accomplished it is an extremely tedious, difficult task, given the complexity of the immune system then after years of testing and millions of dollars, a new drug may emerge that can benefit the population as a whole. Yet, what everyone really needs is the. ability to make this wonder drug himself, just as the person who first produced it did, and that ability cannot be synthesized. Isn’t buying the drug as good as making it? Not by a long shot. The so-called active ingredient in a man-made drug contains very little know-how compared to the original chemical produced by the body. It would almost be fairer to call the drug an inert ingredient.

The reason for this lies at the level of Out cells. The outer membrane of each cell, or the cell wall, is outfitted with numerous sites called receptors. The cell wall itself is smooth, but these receptors are “sticky” they are made of complex molecular chains whose last links are open ended, each one waiting for another molecule to come along and bind with it. In other words, receptors are like keyholes into which only very specific keys will fit. For a drug to work whether morphine, Valium, digitalis, or almost anything else it must be the key that fits some precisely chosen receptor on the cell wall and no other.

The hormones, enzymes, and other biochemical’s produced by Out bodies have superb knowledge about which receptors they should fit into. The molecules themselves actually seem able to pick and choose among various sites it is uncanny to follow their tracks under an electron microscope as they make a beeline to where they are needed. Also the body can release hundreds of different chemicals at a time and orchestrate each one with regard to the whole.

If you hear a hot rod backfire on the street outside your window and jump in your chair, your instantaneous reaction is the outcome of a complex internal event. The trigger for the event is a burst of adrenaline from your adrenal glands. Carried into the bloodstream, this adrenaline signals reactions from your heart, which starts to pump blood faster; from your blood vessels, which contract and · force up your blood pressure; from your liver, which puts out extra fuel in the form of glucose; from your pancreas, which secretes insulin so that more glucose can be metabolized; and from your stomach and intestines, which immediately stop digesting food so that more energy can be shunted elsewhere.

All this activity, happening at a furious pace and with powerful effects everywhere in your body, is coordinated by the brain, which uses the pituitary gland to guide many of the hormonal signals just described, not to mention various other chemical signals that go racing down your neurons to focus your eyes, prick up your ears, jerk your back muscles upright, and swivel your head in alarm . To make this whole reaction happen and then to make it go away again (for the body, unlike a man-made drug, knows how to reverse every one of these processes just as nearly as it began), the same key-in the- lock mechanism is employed everywhere. It is all so deceptively simple, yet if you attempt to duplicate this event with a drugs, the results are nowhere near as precise, orderly, and beautifully orchestrated.

In fact, they are chaotic. Injecting adrenaline, insulin, or glucose separately into the body gives it a crude jolt. The chemicals immediately flood all the receptor sites without coordination from the brain. Instead of talking to the body, they assault it with single-minded insistence. Even though the chemical make-up of adrenaline is identical
where it is derived, the critical ingredient of intelligence must be present; otherwise, the drug’s action is a mockery of the real thing. Here is a related example to show the complicated results of giving I drug that seems simple. Hypertension patients are generally told to bring down their elevated blood pressure with diuretics drugs that take water from the cells and pass it out of the system through urination. This is exactly what the kidneys do all the time as they delicately monitor your blood chemistry to make sure that the balance of water, waste products, and the necessary salts, or electrolytes, is precisely maintained. A diuretic, however, has only one idea in mind, and obsessed with that one idea, it canteens through the body, demanding, “Water! Water!” from every cell it meets.

The result is that the fluid tension in the blood vessels is reduced, which is what the doctor wants to happen, but the water level everywhere else is affected at the same time. The brain may be forced to give up some of its water, which under normal conditions it does only in the direst emergency, causing the patient to feel dizzy and drowsy. In many cases nothing more serious happens, but sometimes other brain functions may also then be thrown off, especially in older patients: if they happen to drink alcohol, even in moderation, these people can become so confused that they forget to drink enough water or to eat properly. This can lead to malnutrition combined . with severe dehydration. In the view of some endocrinologists, the dehydration induced by diuretics in the presence of alcohol or tranquilizers is the leading cause of death among older Americans.

All of these consequences, whether mild or severe, are usually called the undesirable “side effects” of diuretics, but that is not an accurate name. They are just its effects the good and bad ones necessarily come together in the same package. A diuretic basically works by latching onto sodium atoms, causing the body to discard excess salt, and this in turn indirectly brings down the water level in the tissues, since water is bound up with salt in our bodies, just as in sea water. The diuretic cannot help it if too much salt is taken where water is still needed. Since potassium is close to sodium in its atomic structure, the diuretic also causes it to be ‘depleted, leading to weakness, fatigue, and leg cramps. (Less-adverse effects are generally noticed by the leaching of other trace elements, such as zinc and magnesium.) Besides these common signs of potassium deficiency, there can be other complications digitalis, the drug commonly ‘given to heart patients to strengthen their weak heartbeat, becomes more toxic if the body is low on potassium. Ironically, a potassium deficiency is now suspected to be a causal link in high blood pressure, which means that the diuretic may be promoting the very condition it was meant to cure.

The frustrating reality, as far as medical researchers are concerned, is that we already know that the living body is the best pharmacy ever devised. It produces diuretics, painkillers, tranquilizers, sleeping pills, antibiotics, and indeed everything manufactured by the drug companies, but it makes them much, much better. The dosage is always right and given on time; side effects are minimal or nonexistent; and the directions for using the drug are included in the drug itself, as part of its built-in intelligence. Thinking about these well-known facts has led me to three conclusions.

First, that intelligence is parent everywhere in our bodies. Second, that our own inner intelligence is far superior to any we can try to substitute from the outside. Third, that intelligence is more important than the accrual matter of the body, since without it, that matter would be undirected, formless, and chaotic. Intelligence makes the difference between a house designed by an architect and a pile of bricks: For the moment, let’s keep our definition of the word intelligence as simple and practical as possible. Rather than referring to the intelligence of a genius, which may seem both exalted and abstract, I define it simply as “know-how.” There is no doubt, whatever you think about intelligence in the abstract, that the body must be credited with an immense fund of know-how. The body’s inner intelligence is so powerful that when it goes awry the physician is faced with a truly formidable antagonist. Every cell In the body is programmed by its DNA, for example, to divide at a certain rate, producing two new cells after the mother cell splits in half. Like everything else regulated by our inner intelligence, this process is not purely mechanical. A cell divides in response to its own internal need combined with signals generated from the cells around it, the brain, the faraway organs that are “talking” to it via chemical messages, Cell division is a carefully considered and well-thought-out decision ‘except in the case of cancer,

Cancer is wild, anti-social behavior, whereby a single cell reproduces itself without check, heeding no signals from anywhere except, apparently, its own demented DNA. Why ‘this occurs, no one knows, It is a good bet that the body itself knows how to reverse the process, but for some reason, equally unknown to science, it doesn’t always succeed, it is only a matter of time, once the process begins, before the cancer cells , overwhelm a vital organ, crowd out its normal cells, and cause death, When the final crisis comes, the cancer cells perish the rest of the body, doomed by their ungoverned appetite for self-expansion, Medicine has so far not figured out a way to send a message to the cancer cells in time to ward off the tragic fate they have created, The chemicals a physician might use against cancer a.re not at all effective on the level of intelligence, Cancer is endowed with mad genius, while drugs are simple-minded, So the oncologist resorts to a much cruder assault, a form of poisoning, The anti-cancer drug that is administered is generally toxic to the entire body, but because cancer cells are growing at a much faster rate than normal cells, they ingest more of the poison and die off first. The whole strategy is a calculated risk.

The patient must be fortunate; his physician must be extremely knowledgeable about the dosage and timing of the chemotherapy, both of which are absolutely vital. Then the cancer may be defeated, adding years of useful life to the patient’s existence, ironically, the therapy may fail because it strips the body of the very intelligence that usually guards it from disease, Many anti-cancer drugs are extremely damaging to the body’s immune system; they directly suppress the bone marrow, which manufactures our white cells, with devastating effect on the white-cell count in the blood. As the, course of chemotherapy continues, the patient becomes more and more susceptible to new forms of cancer, and in a certain number of cases , as high as 30 percent for breast cancer new cancer appears and the patient dies . Moreover, it is sometimes nor statistically possible to kill every malignant cell. It has been estimated that a typical cancer parent may have 10 billion cancer cells. If his chemotherapy is 99.99 percent effective, there would still be 1 million survivors, more than enough to start over again. Cancer cells are not created equal; some are hardier than others and therefore more difficult to kill. It may be that destroying the weaker cells acts as a kind of Darwinian selection, leaving the fittest to survive.

In that case, chemotherapy would actually promote a more virulent disease than it cured. (Likewise, the persistent staphylococcus infections that patients come down with in hospitals are often highly resistant to antibiotics, because only the most vicious bacteria can live in the sterile, environment of operating rooms and withstand the continual bombardment of penicillin injections.) One can easily conceive of a strain of “super cancer” that might arise from one or two malignant cells that had the strongest resistance to treatment. . In any case, the early promise that chemotherapy would wipe out cancer in our generation, widely believed in the 1950s, has sobered. Now a few cancers at a time are defeated, such as lymphocytic leukemia in children and some kinds of Hodgkin’s lymphoma, while other major killers, such as lung and brain cancers, are virtually untouchable through chemotherapy.

Nothing I have said so far about the body’s know-how is hypothetical. We have all been informed, doctors and public alike, about the body’s wondrous intricacy. Yet we persist in thinking of the body in an obsolete mold, as basically matter, but with a smart technician inside who moves the matter around. This technician was once called a soul; now it tends to be demoted to a ghost inside the machine, but the same emphasis remains. Because we see and touch our bodies, carry their solid weight around -with us, and bump into doors if we don’t watch out, the reality of the body appears to be primarily material such is the bias of our world
But the bias has a huge blind Spot in it.

Despite the overwhelming superiority of the body’s know-how, which scientists freely acknowledge, a minute amount of time and money is spent trying to grasp the living body as a whole, and for very good reason, The Greek philosopher Heraclitus made the famous remark, “You cannot step into the same river twice,” because the river is constantly being changed by new water rushing in, The same holds true for the body, All of us are much more like a river than anything frozen in time and space. If you could see your body as it really is, you would never see it the same way twice. Ninety-eight percent of the atoms in your body were not there a year ago. The skeleton that seems so solid was not there three months ago. The configuration of the bone cells remains somewhat constant, but atoms of all kinds pass freely back and forth through the cell walls, and by that means you acquire a new skeleton every three months.

The skin is new every month. You have a new stomach lining every four days, with the actual surface cells that contact food being renewed every five minutes. The cells in the liver turn over very slowly, but new atoms still flow through them, like water in a -river course, making a new liver every six weeks. Even within the brain, whose cells are nor replaced once they die, the content of carbon, nitrogen, oxygen, and so on is totally different today from a year ago. It is as if you lived in a building whose bricks were systemically taken out and replaced every year. If you keep the same blueprint, then it will still look like the same building. But it won’t be the same in actuality.

The human body also stands there looking much the same from day to day, but through the processes of respiration, digestion, elimination, and so forth, it is constantly and ever in exchange with the rest of the world Certain atoms carbon, oxygen, hydrogen, and nitrogen pass through the body very quickly, being an essential part of the things we use up the fastest food, air, and water. If it were up to only these four elements, we would be creating new bodies for ourselves literally ever month. However, the pace of renewal is slowed by other elements that do not Bow through us very rapidly. The calcium bound into our bones can take a whole year to replace itself. some authorities extend the time to several years. Iron, the component that makes ted blood cells red, is held on to quite tenaciously, being lost mainly through the sloughing of dead skin cells or the actual loss of blood. Even chough the rates of change may differ, change is always there. What I am calling “intelligence” takes on the tale of guiding this change so chat we do not collapse in a heap of bricks. That is one of the most obvious facts about the physiology, but intelligence is so changeable, so quick on the move in other words, so alive that medical text articles devote almost no space to it at all.

To get an idea of how limited our’ current knowledge is, consider the structure of a neuron. The neurons that compose the brain and central nervous system “talk” to one another across gaps called synapses. These gaps separate the tiny branchlike filaments, the dendrites, that grow at the ends of each nerve cell. Everyone possesses billions of these cells, divided between the brain and the central nervous system, and as we saw, each one is capable of growing dozens or even hundreds of dendrites (the total estimated at 100 million), meaning that ac anyone time, the possible combinations of signals jumping across the synapses of the brain exceed the number of atoms in the known universe. The signals also communicate with one another at lightning speed. To read this sentence, your brain takes a few milliseconds to arrange .a precise pattern of millions of signals, only to dissolve them instantly, never to be repeated again in exactly the same way.

In medical school, we were .taught a simple model of how neurons communicate: an e1ecttical charge Forms on one side of the synapse, and when the charge is large enough, it jumps like. spark across the gap to deliver a signal to another nerve cell. Assuming that this is the mechanism (in reality it isn’t), the description we learned in neurology text article in 1966 told us next to nothing about how neurons act in real lire; the article model makes sense only for single cell, laded, stopped in time, and stripped of context. In truth, the action raking place at the gaps in the nervous system is like that of a cosmic computer reduced to a microcosmic scale. This awesome computer operates continuously, handles hundreds of programs at a time, deals in multiple billions of “bytes” of information every second, and, most miraculously of all, knows how to run itself.

It is not really our medical training that was at fault here. How can any text article possibly describe this whole process? To think is to form patterns inside ourselves that are just as complex, fleeting, and rich in their diversity as is reality itself. Thinking is the mirror of the world, and nothing less. Science simply does not have the tools to look at such a phenomenon, which is at once infinite and alive. The living body will not stop to be studied, certainly not as a whole. So when it delivers a shock to’ science, as in a spontaneity, Cure of cancer, medicine all but halts in its tracks, bewildered to find that life does not behave as neatly the laboratory model. In 1986, a shock was delivered that could rum the whole field of brain research on its head: ‘a Mexican neuron-surgeon, Dr. Ignacio Madrazo, successfully implanted healthy new cells into the brain of a patient with Parkinson’s disease.

Not only did the transplant take, which previously was considered impossible, but the patient showed an amazing 85 percent return to normal functioning. Before the surgery, the patient, a Mexican farmer in his late thirties, had been rendered virtually helpless by his disease. Parkinson’s strikes about 1 percent of people over age 50. It begins with muscle tremors, rigidity of the limbs, or a tendency to move very slowly. The immediate cause of these symptoms is a deficiency of dopamine, the same brain chemical that leads to schizophrenia when it is in oversupply. For reasons not yet known, the nerve cells that produce dopamine, located-in a part of the brain stem called the substantia nigra, begin to die, .creating the deficiency. Without enough, dopamine, the brain’s ability to’ regulate muscle movement is impaired and finally lost.

Any or all three of Parkinson’s symptoms grows worse over time, until the patient is totally incapacitated. The playwright Eugene O’Neill contracted Parkinson’s in his fifties. It became increasingly difficult for him to write as his shaking became more severe. He had planned a cycle of four plays that were to be his masterpiece, but his disease destroyed everything: one glance at the surviving manuscripts reveals that O’Neill could barely form the cramped, spidery, pathetically illegible lectors. Through heroic endurance, he managed to commit his words to paper, but no one has ever been able to decipher what they say. In Mexico, Madrazo’s patient, though considerably younger than most Parkinson’s victims, had been confined to his bed, suffering from con’ tent, rhythmic tremors that made him unable co walk without assistance. Afrer the surgery, he could walk, run, feed himself, work in his garden, and, as a moving film of him shows, once again take his young children in his arms.

Dr. Madrazo’s operation opened the door for other Parkinson’s patients, of which there are over a million in the United States alone. By the end of 1987, two hundred similar operations had been performed throughout the world. Madrazo performed twenty of these, all with considerable success. (Previous attempts at the same surgery had failed, as have many since. Madrazo believes that his success is due co the exact location he chooses for his implants.) But the long-term consequences ¥e just now being considered suddenly, and with little warning, neuro-researchers are confronted with the science· fiction possibility of a “brain transplant.”

What makes any brain tissue graft such a shock is that medicine has always believed that the brain could not heal itself. which is why almost all brain damage, either by accident or disease,. has been considered irreversible. Only in 1969 did a researcher in Cambridge, Godfrey Raisman, prove with an electron microscope that damaged nerve cells can sprout new. growth. Now Madrazo has shown that the brain not only
can heal itself but will accept tissue from other organs. His transplant for Parkinson’s was done with cells from the adrenal gland, which also produces dopamine; the surgery can also be performed using brain tissue from another person or even from a pig fetus. Nauru-scientists currently hypothesize that the brains endowed with a complex chemical repair system that was almost totally unknown a few years ago. A Swedish research team has shown that memory loss in rats can be reversed by injecting them with one of the brain’s major repair chemicals, a key protein called NGF, or nerve growth factor. .B y analogy, the brain damage associated with Alzheimer’s disease, which also involves memory loss, may be treatable in the same way. The Swedish experiment also implies an advance over the brain-tissue graft, because it did not use live tissues or require surgery.

One after another, the, basic tenets of brain physiology are having to be reconsidered and drastically modified. The breakthroughs continue to be revolutionary: another Swedish team has shown that nerve cells can be implanted onto the retina of the eye, whose surface is just an extension and spreading out of the optic nerve. After they are implanted, the cells begin to grow new branches, confirming that regeneration in the brain is possible ailed normal. Once again, trust research involved laboratory animals and ‘not human subjects, but the applications for treating blind people are obvious; likewise, other grafts may benefit victims of traumatic brain injury, strokes, and various brain disorders.

I want to ‘emphasize that none of these advances would have been possible, without a change of concept on the part of science. It is disturbing to think that the same doctors who today, in 1989, confidently talk of healing the brain just as confidently pronounced it impossible in 1985. The roots of the brain graft actually go back many years, to 1912, when Elizabeth Dunn, a, researcher at Rockefeller Institute, successfully implanted nerve cells into a moose’s brain. Her research was greeted with total ‘indifference. (One is reminded that penicillium mold was observed to kill bacteria more than 140 times, and accordingly written up in the literature, before Alexander Fleming “discovered” this fact. Previous to him, all the other researchers had been annoyed that their ‘ Carefully grown laboratory cultures were being spoiled by the intrusion of the green mold. Fleming himself threw out his infested bacteria cultures, only later realizing that he had a wonder drug in the making.}

Another pioneer in brain-grail: research, Don M. Gash, now at the University of Rochester, was pulled aside by a senior faculty member at the beginning of his career and told, “Dr. Gash, you’re a young man with a promising career ahead of you. Don’t waste your time on a silly idea that can’t be true.” The very notion that there is a transplant at work arouses intense skepticism. Critics of Madrazo’s procedure have noted that the recovery time of his patients, which begins within a few weeks after the brain cells are implanted, is far too first for the new tissue to “take.” It ,may be , that the brain is repairing itself totally on its .own, releasing chemicals in response to the surgical wound rather than from the new cells (rather like an oyster releasing mother-of-pearl in response to a bit of grit under its. shell).

Perhaps these findings telling us not so much to perform more transplant surgery but rather to look for new abilities in the brain as a living, dynamic organ. For all that it has been glorified by modem medicine, the brain has been the most frozen part of the frozen sculpture model of the body, since it alone could not repair itself. On the face of it, this is a suspicious claim. ‘AII the cells in your body, whether a hair follicle, a neuron, or a heart cell, grew out of one double strand of DNA at the moment of conception. Everything you can do think, speak, run, play the violin, or rule a country builds on a capacity programmed into that one original molecule. Therefore, to say that a neuron cannot heal itself is the same as saying that its DNA has been crippled. Is this a reasonable assumption? Certainly the DNA has decided to become a brain cell instead of a’
cell, and that involves expressing certain parts of its potential while suppressing others.

But this is totally different from saying that any ability in the DNA has been lost. Nothing is lost in DNA. Each cell in the body contains all of DNA’s infinite possibilities all of the time, from the moment of conception until the moment of death. Proof of this exists in the procedure called cloning: theoretically, one can take a cell from the inside of your cheek and, given the right conditions, produce an identical copy of you, or a million identic2.1 copies. The genius of nature is that she did not settle for a million identical clones; indeed, only the lowest organisms consist of identical cells, and most of them are single-celled, like the amoeba. Yet, the distinction between an amoeba and a human being · breaks down at the level of DNA, in this sense: all of the amoeba is contained in its little packet of DNA, and all of you is contained in yours. So it should not be so surprising that a neuron actually can (under circumstances we do not quite understand) decide to drop its rule about nor repairing itself and suddenly begin to do just that. Its DNA is not crippled.

The truth of the matter is that the brain is too complex to be turned into a model, and science by definition works with models. Models are useful, but without exception they have blind Spots built into them. To see brain function, or any function in the body, without a model, you would have to see it as a very abstract and seemingly contradictory thing, as non-change being preserved in the midst of dynamic change. As non-change, the body is solid and stable, like a frozen sculpture.

As change, it is mobile and flowing, like a river. In the scientific worldview inherited from Newton, it has been almost impossible to hold both these aspects together in one’s mind at the same time. I remember a physicist remarking that for Newton, nature was like a billiard game. What he meant was that classical physics studies a collection of solid objects the billiard balls moving along straight lines propelled by fixed laws of motion. The game is to predict their paths, speed, momentum, and so on, like an English gentleman at his evening game of snooker. To make these calculations, however, you have to stop the game and draw a model of it, complete with formulas for the proper angles, trajectories, and so on.

Science has accepted essentially a frozen, geometric way of mapping Out everything that happens in the material world, so quite naturally the idea of the sculpture took precedence over the idea of the river. But the river has nor stopped just to please science the beauty of the human body is that it is new every moment. Yet, how do you make a map of the body fur every moment? That is the next dilemma we have to confront. If We can solve it, we will come much closer to what we want, nor more knowledge to put into libraries, but new abilities to program into our cosmic computer.

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The Body Has A Mind Of Its Own

October 22, 2009 Uncategorized

When I said that no one can honestly claim to know the cure for breast cancer, I was telling a half-truth. If a patient could promote the healing – process from within, that would be the cure for cancer. Healing episodes like Chitra's come about when a radical shift takes place inside, removing fear and doubt at the same time as it removes the disease. Yet, the exact location of this shift opens up profound mysteries. It defies medical wisdom to answer even the most basic question: Was the shift in Chitra's mind, in her body, or both? To find out, Western medicine has recently begun to move away from drugs and surgery, the mainstay of every doctor's practice, toward the .amorphous, often perplexing field loosely known as mind-body medicine. The move was almost a forced one, because the old reliance on the physical body alone had begun to crumble.

Mind-body medicine makes many doctors extremely uneasy. They feel it is more a concept than a true field. Given a choice between a new id and a familiar chemical, a doctor will trust the chemical penicillin digitalis, aspirin, and Valium do not need any new thinking on the patient's part (or the doctor's) to be effective. The problem comes in when the chemical isn't effective. Recent surveys taken in England and America have shown that as many as 80 percent of patients feel that their underlying complaint, their reason for going to the doctor, was not satisfactorily resolved when they left his office. Classic studies going back to the end of World War II showed that patients left the Yale Medical School hospital sicker than the day they arrived. (These are paralleled by similar studies that showed that patients with psychiatric complaints improved more while they were on the waiting list to see a psychiatrist than after they actually saw him so the situation isn't simply one of exchanging a body doctor for a head doctor.)

A miracle cure, then, simply throws into high relief the need to reexamine some of medicine's basic concepts. Our current logic of healing can be impressive, or at least good enough, as when we apply penicillin to cure an infection, but nature's logic can be awe-inspiring. Many physicians have stood in wander witnessing such cures as Chitra's without having a clue how to explain them; the standard term for them is spontaneous emission, a convenient tag that says little more than that the patient recovered by himself. Spontaneous remissions are quite rare:- one study in 1985 estimated that they occur once in every twenty thou 'sand diagnosed cancer cases; some specialists believe they are much rather (fewer than ten per million), but no one knows for sure.

Recently I spent an evening with a leading oncologist, or cancer specialist, from the Midwest, a doctor who treats thousands of patients every year. I asked him if he knew of any spontaneous remissions. He shrugged and said, "I feel uncomfortable with that term. I have seen , rumors completely regress. It's very rare, but it happens."

Did, these regressions sometimes happen totally by themselves? He admitted that they occasionally did. He" thought for a moment and mentioned that certain kinds of melanoma an extremely lethal skin cancer that kills very quickly are known to disappear by themselves. He couldn't explain why this happened. "I don't stop to think about these rare incidents," he said. "Treating cancer is a matter of statistics we go with the numbers. A huge majority of patients respond to certain · lines of treatment, and there just isn't time to find out about the infinitesimal minority who recover for some unknown reason. Bes.!des, it ' is our experience that many of these regressions are only temporary." Did he think complete regressions were rarer than one in a million? No, he answered, not that rare.

Then, as a scientist, didn't he want to find our the mechanism that lies behind them, even if the odds are one in a million, or one in ten million? Again he shrugged. "Of course there must be a mechanism behind it," he conceded, "but my practice is not set up to look into that. Let me give you an example: eight years ago, a man came to see me complaining of a painful chest cough. We X-rayed him, and it turned our that he had a large tumor between his lungs. He was admitted to the hospital, we took a biopsy, and the pathologist's report diagnosed the tumor as oat-cell carcinoma. This is an extremely deadly, very fast-growing malignancy.

"I told my patient that he must have immediate surgery to relieve the pressure that his rumor was creating, followed by radiation and chemotherapy. He was quite disturbed by the prospect of treatment and refused. I completely lost track of him after that. Eight years later, a man . came to see me with an enlarged lymph node in his neck. I took a biopsy, and it turned out to be oat-cell carcinoma. Then I realized that it was the same man.

"We took chest X rays, and there was no trace of lung cancer. Normally, 99.99 percent of untreated patients would have died in six months; as many as 90 percent would not live five years even with maximum therapy. I asked him what he had done for the earlier cancer, and he told me. he hadn't done anything he had just decided he was not" going to let himself die of cancer. And he may refuse treatment again with this second cancer."

By definition, scientific medicine deals in predictable results. Yet,. whenever spontaneous remissions appear, their behavior is completely unpredictable. They can occur without the presence of any therapy, or they can accompany conventional cancer treatment. The myriad alternatives approaches to cancer available in the United States today may each have distinct merits, but no one has proven that they promote spontaneous remissions any better than standard radiation and chemotherapy, nor are they apparently any worse. How advanced the cancer is seems not to matter, either. Both tiny tumors and extremely large masses of malignancy can disappear, virtually overnight. Because of their rarity and because they happen as if by chance, spontaneous remissions have so far taught us very little either about the cause of cancer or about how an "impossible" cure is achieved.

It seems reasonable to suppose that the body is fighting cancer all the time and winning a huge majority of the battles. Many kinds of cancer can be induced, either in test tubes or in laboratory animals, using toxic substances (carcinogens), fatty diets, radiation, high doses of stress, and viruses, among other things. Since we are subjected to all of these at a furious rate, they must be causing damage inside us. DNA is known to break down under these extreme conditions; usually, however, it knows how to repair itself or to detect the 'damaged material and discard it.

This means that early cancers are probably being detected and combatted in the body on a regular basis. If you take this process and step it up in intensity, you have the "miracle" of a spontaneous remission. It is no miracle at all, in fact, but a natural process that has yet to be explained, just as curing pneumonia with penicillin would be a miracle if you could not explain it through the germ theory of disease. The point is that the mechanism behind miracle cures is not mystical or random and it deserves to be investigated.

In ordinary practice, once the miracle is over, the doctor goes back to his routine, including his routine concepts. Even these, however, the stock in trade of medical school, have buckled. To give just one example: Since its inception as a field of rational scientific study, medicine has accepted the degeneration of brain function in elderly people as a natural occurrence. This deterioration was thoroughly documented with "hard" filings as we age, our brains shrink, grow lighter, and lose millions of neurons every year. We have our full complement of neurons by age 2, and by age 30, the number starts to decline. The loss of any single brain cell is permanent, since neurons do not regenerate. On the basis of this well-known fact, brain decline seemed to be scientifically valid; sadly but inevitably, co grow old must lead co memory loss, decreased reasoning ability, impaired intelligence, and related symptoms.

These time-honored assumptions, however, have now been shown to be wrong. Careful study of healthy elderly people–as opposed to the sick, hospitalized ones whom medicine habitually studied-his revealed that 80 percent of healthy· Americans, barring psychological distress (such as loneliness, depression, or lack of outside stimulation), suffer no significant memory loss as they age. The ability to retain new information can decline, which is why old people forger phone numbers, names, and the reason for walking into a room; but the warily to remember past events, called long-term memory, actually improves. (One authority on aging quotes Cicero, who declared, "I've never beard of an old man who forgot where his money was hidden.")

In tests where 70-year-olds were matched with 20-year-olds, the older people performed better than the younger in this area of memory. After they practiced the other kind of memory called shaft-term memory' for a few minutes every day, the older group could almost match the younger subjects, who were at the prime of mental functioning. Perhaps the "prime of life" should be extended. 'The secret, as with almost every other "natural" decline in old age, depends on habits of mind, not the circuitry in the nervous system. As long as a person stays mentally active, he will remain as intelligent as in youth and middle age. People will still _lose over one billion neurons throughout their lifetime, ,it an average rate of 18 million per year, but this loss is compensated for by another structure, the branchlike filaments called dendrites, which connect the nerve cells to one another.

A nerve cell tends co be highly individual in shape, but typically it has a bulbous central section from which thin arms radiate, like an .octopus. These arms, or axons, end in a swirl of tiny filaments that looked treelike to the early anatomists, so they named them dendrites after the Greek word for "tree." Dendrites, which can vary in number from less than a dozen to more than a thousand per cell, serve as contact points, allowing the neuron to send signals to its neighbors. By growing new dendrites, a neuron can open new channels of communication in every direction, like a switchboard sprouting extra lines.

It is not known how a thought is actually formed among brain cells or how the bewilderingly vast number of connections interrelate millions of dendrites come together at major junction points in the body, such as the solar plexus, not to mention the billions upon billions in the brain itself. But experiments have shown that new dendrites can be grown throughout life, up to advanced old age. The current view is that this new growth easily provides us with the physical structure for unimpaired brain function. In a healthy brain, senility is not physically normal. A rich multiplication of dendrites might even lie behind growing wise in old age, a time when more and more of life is seen in its totality in other words, more interconnected, Just as the nerve cells are more interconnected through their ne dendrites.

This example illustrates how radically wrong medicine can be if it insists that matter is superior to mind. To say that a nerve cell creates thoughts may be true, but it is just as true to say that thinking creates nerve ·cells. In the case of the new dendrites, it is the habit of thinking, remembering, and being mentally active that creates the new tissue. Nor is this an isolated finding. Curiously enough, as soon as the .concept of the "new old age" was permissible in the eyes of doctors, our views of many forms of degeneration began to alter.

As long as you exercise, for example, your body's musculature will not .lither, and your strength will be unimpaired. for life, although there will be a slow decline in stamina. You can train for a marathon at 65, provided you are in good physical shape and train sensibly. Similarly, your heart changes with age, growing less resilient and pumping less blood per beat, bur heart disease and hardening of the arteries, thought absolutely normal with old age a few decades ago, are now seen as avoidable, too, depending on diet and lifestyle. Strokes, another given of old age, have declined by 40 ·percent Just in the last decade, thanks to better control of hypertension and less fat in our diets. A large percentage of "unavoidable" senility has been traced to vitamin deficiency, poor diet, and dehydration. The overall result of these findings is that old age is being drastically reconsidered; a less obvious result is that the whole body, at any stage of life, has to be rethought.

What is happening on every front in medicine is that the healthy body is showing itself to be more resilient and versatile than was hiterto suspected. Whereas medical school teaches that germ A causes disease B and is treated by drug C, nature seems to feel that this is only one option among many. The mental approach to treating cancer, for instance, would have been ridiculed a decade ·ago. Bur people do seem able to participate in their cancer treatment, and even to control the course of the disease, by using thoughts. In 1971, Dr. O. Carl Simonton, a radiologist at the University of Texas, met a 61 -year-old man with throat cancer. The disease was very far progressed; the patient could hardly swallow, and his weight had dropped to 98 pounds.

Not only was the prognosis extremely poor the doctors gave him a 5 percent chance of surviving five years after treatment but the patient was already so weak that it seemed unlikely he would respond well to radiation, which is the standard therapy for this condition. In desperation, but also curious to try a psychological approach, Dr. Simonton suggested that the man enhance his radiation therapy through the use of visualization. He was taught to visualize his cancer as vividly as possible. Then, using any mental picture that appealed to him, he was asked to visualize his immune system as the white blood cells successfully attacked the cancer cells and swept them our of the body, leaving only healthy cells behind.

The man said he envisioned his immune cells as a blizzard of white particles, covering the tumor like snow burying a black rock. Dr. Simonton had him go home and repeat this visualization at intervals throughout' the day. The man agreed, and soon his rumor seemed to be shrinking. In a few weeks it was definitely smaller, and his response to radiation was almost free of side effects; after two months, the tumor was gone.

Naural1y, Dr. Simonton was surprised and barred, though elated that the psychological approach had been so powerful. How does a thought defeat a cancer cell? The mechanism was totally unknown in face, given the fiendish complexity of the immune system and the nervous system, both of which were obviously involved here, the mechanism might be unknowable. For his part, the patient accepted his cure without undue surprise. He told Dt. Simonton that" arthritis in his legs kept him from going scream-fishing as much as he liked. Now that the cancer was gone, why not try visualizing the arthritis away too? Within a few mote weeks, that is exactly what happened. The man remained free of both cancer and arthritis for a follow-up period of six years.

This now-famous case is a landmark in mind-body medicine, but unfortunately it is not the whole Story. Dr. Simonton's visualization therapy (it has branched out into a brood mind-body program) does not reliably cure cancer. One of my patients used it with success to cute herself of breast cancer, I believe, although she practiced the technique on her own and not under a doctor's scrutiny. Long-term statistical studied however, dispute' whether such sporadic results are any better than those of conventional cerement. At present, conventional therapy has a big edge. If a woman with breast cancer, for example, detects the tumor while it is still very small and localized, the chances of curing hart (a "cure" means surviving at least three years without a recurrence of the disease) are currency better than 90 percent. In comparison, the number of spontaneous remissions, ac the most generous estimate, would be well below of 1 percent. Until a mental or other alternative therapy outperforms radiation· and chemotherapy, it will" not become the treatment of choice. Although patients may long for such approaches, most decors still fear and distrust them.

But even if Dr. Simonton's patient were one of a kind, he is enough to rock our conception of how the body cures itself, for here is nature finding a way to combat death that no doctor had ever tried and here also is the dark possibility that what the doctor sullenly tries is not helping nature but stifling it.

Curious and adventurous doctors have flocked to experiment with mind-body innovations over the last decade, from biofeedback and hypnotism to visualizations and behavior modification. The results across the board have been amorphous and hard to interpret. Psychologist Michael Lerner spent three years conducting an in-depth study of forty clinics offering alternative approaches to cancer, whose methods ranged from herbs and macrobiotics to visualization of positive mental images. He round that these "complementary cancer centers" were sought nut by patients who were generally well educated and prosperous, that the doctors running the clinics were also serious and well intentioned,-but that nothing close to a cure for , cancer had been discovered anywhere he visited.

When he interviewed the patients, a fairly large proportion (40 percent) thought that they had experienced at least a temporary improviser in the quality of their lives. Another 40 percent repined that they experienced actual medical improvements in their condition, lasting from a few days to a number of years. About 10 percent fell at the extreme ends of the spectrum, one group saying that they got nothing from the treatment and the other that they were now pan ally or wholly recovered from their disease. Generally, the record of a1temarive approaches is that they give a measure of comfort and relief to patients, but disappointingly, the remission 'rates are not radically of standard therapy,

There are other problems that run deeper than inconsistent results: the mind-body field continues to be plagued by an inability to rigorously prove its basic tenet, that the mind influences the body toward .either health or disease. It seems utterly self-evident that sick people and healthy people enjoy different states of mind, but the causal connection is still elusive. In 1985 a major study of breast cancer conducted at the 1 University of Pennsylvania failed to find any correlation between the mental attitude of patients and their chances of surviving their disease beyond two years. In an editorial accompanying the study, which appeared in the prestigious New England Journal of Medicine, the whole concept of emotions affecting cancer was denounced. "Our belief in disease as a direct reflection of mental states," the editorial declared, "is largely folklore."

In response, letters deluged the journal, most of them from physicians who heatedly disagreed with the editorial's conclusion. It certainly seems unreasonable to discount mental attitudes as a factor in illness, much less as folklore. Every practicing physician knows that the patient's will to recover plays a vital part it) his treatment. Wedded as they are to "hard" medicine, most doctors nonetheless cannot condone the idea that attitude, belief, and emotions do not play their part. Hippocrates stated at the dawn of Western medicine that "a patient who is mortally sick might yet recover from belief in the goodness of his physician." Numerous modem studies have corroborated this, by showing that people who trust their doctor and surrender themselves to his care are likelier to recover than those who approach medicine with distrust, fear, and antagonism. In the wake of the editorial, tempers t1ared and lines of allegiance were drawn, while the issues became even more confused. Three separate studies of breast-cancer survival rates from the mid-1980s came up with three entirely different results.

In one, the women who displayed strong positive attitudes tended to outlive those who were negative, and it did not matter if their diseases were more advanced positive emotions, it seemed, helped them · recover from a late-stage, metastasized cancer, while patients with negative emotions died from small tumors that had been diagnosed relatively early.

A second study, however, found that any strong attitude, if expressed rather than held back, helped in survival of this very deadly disease. While the first finding bolsters common sense the idea that positivity is better than negativity the second does much the same from another angle, the idea being that it is better to fight than to give up. Publicity was given to a so-called cancer personality, who bottles up emotions and somehow converts repression into malignant cells. The opposite would ·be the "strong will to live" type, who can be either positive or negative.

All of this follows a certain logic, except for the ·stud that appeared in the New England Journal of Medici1l$ to begin with, seconded by supporting studies, which found no correlation between any emotional pattern and surviving breast cancer beyond two years. Even as it grew in popularity, becoming one of the most welcome innovations since the Salk vaccine, the concept of mind-body  medicine was shaken. Now, a familiar pattern has emerged, in which the public is informed of some elating breakthrough, followed by disappointing clinical results· that are generally known only in medical circles.

A classic example. was the division of heart-attack patients, more than three-quarters of them middle-aged males, into high-risk Type A personalities and low-risk Type B's. The Type A personality was supposed to be a hard-driving, compulsive worker, constantly racing deadlines and churning his system with stress hormones, as opposed to the relaxed, tolerant, more balanced Type B. Type A suffered from "the disease of being in a hurry"; therefore, it seemed logical that his heart would eventually rebel, leading to a coronary.

Unfortunately, controlled studies have indicated that this widely accepted division is not so neat. It turns out that most people have some Type A in them .and some Type B, and that relevance for stress varies widely, with certain groups stating that they thrive on it. Finally, a. 1988 study found that if a man actually has a heart attack, Type A's survive better than Type B's. Their drive to succeed apparently turns into a benefit once the coronary strikes.

The intricacies of the mind· body relation were not to be easily solved. If one asks why a positive mind cannot be easily correlated with good health it appears to be one of the most obvious facts of life the an sweet has to do with what you mean by "mind" in the first place. This is not a philosophical question but a practical one. If a patient .comes in with cancer, is his mental state judged by how he feels on the day of the diagnosis, long fore, or long afterward? Dr. Lawrence LeShan, author of me pioneering studies from the 19505 correlating emotions to cancer, went back into the childhoods of cancer patients to find the black seed that poisoned their psychology, and he theorized that it lay dormant in .the subconscious fur year; before inducing their disease. 1n my own practice, I saw a lung-cancer patient who had lived comfortably win a coin-sized lesion in his lungs for five years.

He did not even suspect that it was cancerous, and since he was in his sixties, the lesion was growing quite slowly: However, as soon as I cold him that the lesion was consistent with a diagnosis of lung cancer, he became terribly agitated. Within a month he started to cough up blood; within three was dead. If his state of contributed to this untoward haste, it apparently acted quickly. This patient could live with his rumor, but he couldn't live with the diagnosis. Even more basic is this question: Is the "mind" that a doctor is interested in the patient's overall personality, his subconscious, his attitudes, his deepest beliefs, or something not yet understood and defined by psychology? It may be that the relevant aspect of the mind involved in getting sick or getting well is not even specifically human.

An Ohio University study of heart disease in the 1970s was conducted by feeding quire toxic, high-cholesterol diets to rabbits in order to block their arteries, duplicating the effect that such a diet has .on human arteries. Consistent results began to appear in all the rabbit groups except fur one, which strangely displayed 60 percent fewer symptoms. Nothing in the rabbits' physiology could account for their high tolerance to the diet, until it was discovered by accident that the student who was in charge of feeding these particular rabbits liked to fondle and pet them. He would hold -each rabbit lovingly for a few minutes before feeding it; astonishingly, this alone seemed to enable the animals to overcome the toxic diet: Repeat experiments, in which one" group of rabbits was treated neutrally while the others were loved, came up with similar results. Once again, the mechanism that causes such immunity is quite unknown it is baffling to think that evolution has built into the rabbit mind an immune response that needs to be triggered by human cuddling,

There is even a possibility, many doctors would contend, that the mind is a fiction, medically speaking, When we think that it is sick, what is really sick is the brain, By this logic, the classical mental disorders depression, schizophrenia, and psychosis are actually brain disorders, This logic has obvious inadequacies: it is like saying that car wrecks should be blamed on automobiles, But the brain, being a physical organ that can be weighed and dissected, makes medicine feel more secure than does the mind, which has proved impossible to define after many centuries of introspection and analysis, Doctors are quite happy not to be called upon as philosophers,

The ability of today's psychotropic, or mind-influencing, drugs to relieve the major symptoms of mental illness, such as depression, mania, anxiety, and hallucinations, is much greater than any treatment available in the past, Chemical psychiatry is likely to vie with its exact opposite, mind-body medicine, as the medical revolution of our time, It has hard clinical results to back it up, including numerous indications that chemical imbalances in the brain are directly linked to mental illness,

Nothing could appear to be more all-encompassing than the full-blown' madness of a chronic schizophrenic, who suffers from hallucinatory visions and inner voices, distorted thinking, and often complete physical and mental disorientation, To ask a schizophrenic what day it is can throw him into bewilderment and shivering terror, However, the structural difference between this state of mind and sanity may be traceable to one minute biochemical called dopamine, which is secreted by the brain, The dopamine connection, known for two decades, held that schizophrenics overproduce this chemical, which plays an important role in processing both emotions and perceptions a hallucination would thus be a perception of the outside world that has gotten scrambled in the brain's chemical coding.

This hypothesis was further simplified in 1984 when a psychiatrist at the University of Iowa, Dr. Rafiq Waziri, reviewed what was known about the brain chemistry of schizophrenics and narrowed the defect down to an even smaller molecule called serine, a common amino acid found in most protein foods. Serine is thought to be an early link in the manufacture of dopamine. Unable to metabolize serine correctly, the brains of schizophrenics apparently overproduce dopamine to offset the lack the exact process is still unknown. Could it be that full-blown schizophrenia, considered the most bizarre and complex of mental disorders, depends on how well you digest your food? Earlier findings at M.LT. have already shown that the brain's basic chemistry is so variable that it can be modified by a single meal.

Dr. Waziri bolstered support for his theory by taking a group of long-term schizophrenics and feeding them a dietary supplement of glycine, a chemical that serine is supposed to build as part of the dopamine mechanism. Perhaps the extra glycine would bypass the serine defect, Waziri reasoned, and bring dopamine back into balance. In the trial group, a few schizophrenics responded quite dramatically they were able to stop their medications without having any psychotic episodes. For the first time in years, their thinking was free from both their disease and the mind-numbing drugs used to treat it.

A dietary approach to mental illness would be far more benign than current therapies, The possibility of finding more dietary links is also tantalizing. At least one best-selling diet article has jumped the gun by listing "happy foods "and "sad foods," on the theory that the amino acids in these foods go directly to the brain and are made into chemicals " that produce either positive or negative moods. Milk, chicken, bananas, and leafy greens are among the happy 'foods., because they stimulate dopamine and two other "positive" brain chemicals. Sugary and fatty foods, on the other hand, are typically sad foods, because they stimulate acetylcholine, a "negative" chemical. Critics say, quite justifiably, that brain chemicals are not so simple can a schizophrenic's high dopamine levels be considered positive? Nor does it seem that changing the intake of amino acids leads directly to more of a desired brain chemical, just as the amount of cholesterol in your diet does not directly correlate with the amount in your blood.

If you can eat your way to sanity, or even a better mood, then the basic issues in mind-body medicine become even more confused. Can you trust the mind to cure arthritis and at the same time hold that eating chocolate will make you depressed? This would imply a self-contradiction, that mind is dominant over matter except when matter is dominant over mind. In the current atmosphere of ambiguous findings, the two opposite positions treat the body through the mind, treat the mind through the body equally up in the air.

None of the confusion has been adequately clarified, and as a result, the subjective world of the mind remains a treacherous force, capricious in its ability to heal, equally capricious in its ability to bring illness. Many doctors, because of their materialistic. bias, would be thrilled to conclude that chemicals must be the answer to all our mental and physical mysteries.

I don't think they can be. In my specialty of endocrinology, some of the first chemicals that affect the mind, the endocrine hormones, were discovered. Every day I see patients who display mental symptoms that are traceable to defects in their hormonal balance the distorted thinking of a diabetic going into a low-blood-sugar reaction, the mood shifts of the menstrual cycle, and even a characteristic depression that is the earliest warning sign of certain cancers (a tumor in the pancreas, for example, may be too small to detect, yet it will release cortical and other "stress hormones" into the bloodstream, causing the patient to feel depressed).

Despite this, I see too many flaws in the argument that a deeper knowledge of body chemistry is all we need the body has too many chemicals (literally thousands of them), they are produced in bewilderingly complex patterns, and they come and go too &St, often in fractions of a second. What controls this constant flux? We cannot leave the mind out of the mind-body connection altogether. To say that the body heals itself using only chemicals is like saying that a car shifts gears using only the transmission. Clearly it takes a driver who knows what he is doing. Although medicine has spent several centuries trying to hold on to the idea that the body runs itself alone, like a self-motivated machine, there must be a driver here, too. Otherwise, our body's chemistry would be a jumble of floating molecules instead of the incredibly ordered and precise machinery that it so obviously is.

In a more naive age, the driver was thought to be a tiny man, called the homunculus, who sat in the heart and performed all the gear shifts needed to run the body. The homunculus went out in the Renaissance, when anatomists began for the first time to dissect cadavers and verify what was inside them. The homunculus wasn't found inside the heart (neither was the soul), but that left a huge, glaring gap between the mind and the body. Many scientists since have tried to fill the gap with the brain, saying that the brain's function is to order and control all other functions in the physiology; bur this answer begs the question, because the brain is just another machine. The driver still needs to be there. I will argue that he is, but he has become something much more abstract than the homunculus or even the brain he is built into the intelligent power that motivates US to live, move, and think.

Can that be proved The next step for US is to work our way deeper into the body's inner intelligence, to try to find out what motivates it. The territory of mind-body medicine has no givens and no inflexible rules, which is all to the good. For decades, medicine has known that much disease has a psychosomatic component, yet dealing with that component has been like trying to' harness the wind. Inside us there must be a "thinking body" that responds to the mind's commands, but' ~here could it be and what is it made of?

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After The Miracle

October 21, 2009 Uncategorized

Several times in my medical career I have been privileged to witness miraculous cures. The most recent began last year when a 32-year-old Indian woman came to see me in my office outside Boston. She sat quietly facing me in a blue silk sari. To keep her composure, she clasped her hands tightly in her lap. Her name was Chitra, she said, and together with her husband, Raman, she ran a neighborhood import store in New York City.

A few months earlier, Chitra had noticed a small lump in her left breast that was sensitive to the touch. She underwent surgery to remove it, but unfortunately the surgeon found that the lump was malignant. When he explored further, he detected that the cancer had spread to her lungs.

After removing the diseased breast and a large portion of around it, Chitra’s doctor gave her initial doses of radiation and then
placed her on intensive chemotherapy. This is standard procedure for treating breast cancer and saves many lives. But the
lung cancer was going to be much .harder to treat; it was obvious to everyone that Chitra was in a very
precarious position.

Examining her, I noticed that she was very anxious. When I tried to reassure her, she surprised me with a touching statement: “I don’t mind for myself if I have to die, but my husband will be so lonely without me. Sometimes I pretend to be asleep and then sit up all night, just thinking about him. I know Raman loves me, but after I’m gone, he will start seeing American girls. I can’t bear to lose him to an American girl.” She stopped and looked at me with suffering in her eyes. “I know I shouldn’t say that, bur I think you understand.”

You do nor get used to the sorrow that cancer creates, but I felt a deeper sorrow from knowing that time· was Chitra’s enemy. For the moment, she still looked healthy. She had even managed to hide her ‘ disease from her relatives, dreading having to be watched as she wasted away. We both knew it was going to be very bad for her. ‘No one can say that he knows a cure for advanced breast cancer. Conventiona1 therapy had provided all that it could for Chitra Given That her cancer had already spread to another organ, the statistics said hat her chance of surviving for five years was less than 10 percent, even with the most intensive routine of chemotherapy that could be safely administered.
I asked bee to start a new course of treatments, as prescribed by Ayourveda.

Like me, Chirra had grown up in India, but she had little idea of Ayuneda. Her grandparents’ generation was the last to “believe” in it, I would imagine today, every progressive Indian living in a big city would prefer. Western medicine if he could afford it. To explain to Chitra why I wanted her seemingly to turn her back on progress, I told her that her
cancer was not just a physical disease but a holistic one. Her whole body knew she had cancer and was suffering from it; a tissue sample taken from her lungs would show that malignant cells had migrated there, while a sample. from her liver would be negative. Yet, her liver had the so blood coursing through it, and therefore it picked up the
signals of disease that were coming from the lungs. This in turn affected its own functions.

Similarly, when she felt pain in her chest or had to sit down owing to shortness of breath, signals were racing throughout her body, going to and from her brain. Sensing the pain, her brain had to respond to if. The fatigue she was feeling, along with her depression and anxiety, was a brain response that had physical consequences. So it was wrong to think of her cancer as just an isolated tumor that needed to be destroyed. She had a holistic disease and for that she needed holistic medicine.

The word holistic, which tends to offend orthodox doctors, simply means an approach that includes the mind and body together. I believe Ayurveda does this better than any alternative, although it may not be very apparent on the surface. In fact, many well-publicized mind-body techniques such as hypnosis and biofeedback are far more flashy than Ayurveda. If Chitra had gotten sick at home in Bombay, her grandmother might have fixed her some special meals, brought home medicinal herbs in a brown paper sack from the Ayurvedic pharmacy, and . insisted that she stay in bed. Various purgatives and oil massages might be prescribed to clean the body of toxins generated by the cancer. If there was a spiritual tradition in the family, she would have begun to meditate. In essence, I was going to have her do these same things, with a few additions. There is as yet no scientific reason why any of this should work, except that it does. Ayurveda has hit on something deep in nature. Its knowledge is rooted not in technology but in wisdom, which I would define as a reliable understanding of the human organism gathered
over many centuries.

“I want you to go to a special clinic outside Boston for a week or two,” I told Chitra “Some things that will happen to you there will seem highly unusual. You are used to the idea of a hospital as a place with respirators, IV rubes, transfusions, and chemotherapy. By that standard, what we will do for you at this clinic will seem like nothing. Basically, I want to get your body into a deep, deep state of rest.”

Chicra was a trusting person; she agreed co go. In p”;’c, of course, she I had no alternative. Modern medicine had done all it could, using the strategy of physical assault on her cancer. The initial advantage of as salting a disease is that you hope to wipe it out physically as soon as possible. The tremendous disadvantage is that the whole body is damaged in the assault on one of its parts. In the case of chemotherapy, there I is the very real danger that the immune system will become so weakened I that the door is opened for other cancers to develop in the future. How
ever, untreated breast cancer is considered deadly, and today’s medicine is good at wiping it out over the short run. In a climate of opinion ruled by fear, people prefer to run the risks of the cure rather than the disease.

I referred Chitra to the clinic where I work, in Lancaster, Massachusetts. She stayed for a week and received treatments; she also learned an outpatient program to use at home that included a change of diet, some Ayurvedic herbs, a specific daily routine including simple yoga exercises, and instruction in meditation. These measures look different on the surface, but underneath they all aimed at bringing her day-to-day existence to a settled, restful state, building a foundation for healing. In Ayurveda, a level of total, deep relaxation is the most important precondition for cuting any disorder. ‘The underlying concept is that the body knows how to maintain balance unless thrown off by disease; therefore, if, one wants to restore the body’s own healing ability, everything should be done to bring it back into balance. It is a very simple notion that has profound consequences. Chitra was also given two special mental techniques that went directly to the root of her cancer. (I will say more about these later.)

Chitra followed her program faithfully and came back to see me every six weeks. She also continued the course of chemotherapy set up by her doctor at home in New York. When we talked about that I said, “If I could confidently put you on nothing but Ayurveda, I would-.the deterioration in your physical state would then be much less. But you came to me a very sick woman, and we know that the chemotherapy works as an outside approach. Let’s combine the outer and the inner and hope that they add up to a real cure.”

For almost a year I followed Chitra’s progress. She always listened with a trusting attitude, yet as she returned for each visit, it was clear that she was ‘i0t improving. Her lung X rays were still bad, her shortness of breath grew worse, and she began to look weaker and more dejected as the disease advanced. Her voice took on a note of panic. Finally the day came when Chitra did not show up for her appointment. I waited out the week and then called her home.

The news was not good. Chitra’s husband, Raman, told me that she had suddenly developed a high fever and had to be hospitalized over the weekend. For some time her lungs had been seeping fluid into the pleural cavity that surrounds them, and her doctor suspected that an infection had set in. Given her grim prognosis, there was no guarantee that Chitra would ever leave the hospital.

Then a very curious thing happened. After a day or two on antibiotics, Chitra’s fever went from 104 degrees F. back down to normal, which puzzled her attending physician. It is very unusual for a high-grade fever to reverse itself so rapidly if the underlying cause is an infection in a terminally ill patient. Could there be another cause besides infection? He decided to take chest X rays, and the next day Raman called me sounding both exhilarated and confused. “She doesn’t have cancer anymore!” Raman told me jubilantly over the telephone. “What do you mean?” I asked, taken aback. “They can’t find any cancer cells at all nothing.” He was almost unable to contain himself. “Chitra’s oncologist at first was sure that they had X-rayed the wrong patient and wanted to take some more pictures, but now he’s convinced.”

Overjoyed, relieved, and unable to explain this sudden stroke of salvation, Raman regarded his wife’s recovery as a miracle. When I called Chitra in her-hospital room, she kept crying into the phone, “You did it Deepak,” while I kept insisting, “No, no, Chitra, you did it.” I had never anticipated that such a rapid cure would result from her treatments, either conventional or Ayurvedic. In retrospect, I see that her high fever was a kind of burn-off from the dying cancer a process known .as tumor necrosis. But the exact mechanism involved has no explanation. If there is such a thing as a miraculous cure, this was one, I was certain. Within a few weeks, however, our mutual jubilation began to change. Chitra’s “miracle” wasn’t holding.

It eroded first within herself: instead of being able to trust in her inexplicable recovery, she became conflicted, morbidly afraid that the cancer would return. She called to ask me if she should resume chemotherapy. “It’s been two months since the cancer disappeared,” I said. “Does your doctor find any new cancer cells?” “No,” Chitra admitted, “but he thinks ·that the chemotherapy cured me and that I should continue with it.” I began to feel frustrated. I knew, as did her attending physician, that the particular chemotherapy Chitra had received was not known to pro. duce sudden, total recoveries of this kind, certainly not in advanced cases where the cancer had begun to spread to other sites in the body. Also, it was becoming obvious that she was being worn down past endurance. The chemotherapy had caused almost constant nausea, and her hair had fallen out in frightening amounts, adding to the shame she felt following her breast surgery.

All of trust compromised the Ayurvedic treatments we were trying. If even higher doses of chemotherapy were given, she would become more depressed, more prone to infections, and weaker in every way. Yet, at the same time, I did not have a strong enough reason to tell her not to proceed. What if she suffered a relapse in six months and died? “Go ahead with your chemotherapy,” I advised, “but stick with our program, too, okay?” She agreed . For several months more, Chitra remained free of disease, but she also remained disturbed and mystified. It seemed that Chitra’s cancer was easier to defeat than the sinister ‘ doubt that was creeping back into her lire, defying het to be well. China’s agonizing dilemma is the tea! starting point of this article. For her to be well again, she needed an explanation. What had happened to her? Was her cure a miracle, as she thought at first, or only a temporary stay of execution, as she came to dread? By going deeper into the mind-body connection, I believe an answer can be found.

Research on spontaneous cures ‘ of cancer, conducted in both the United States and Japan, has shown that just before’ the cure appears, almost: every patient experiences a dramatic shift in awareness. He knows that he will be healed and he reels that the force responsible is inside himself but not limited to him it extends beyond his personal throughout all of nature. Suddenly he feels, “I am not limited to my body. All that exists around me is part of myself.” At that moment, such patients apparently jump to a new level of consciousness that prohibits the existence of cancer. Then the cancer cells either disappear, literally overnight in some cases, or at the very least stabilize without damaging the body any further.

This leap in consciousness seems to be the key. It does not have to come in a flash, however. China was cultivating it deliberately, through her Ayurvedic techniques. Therefore, het ability to Stay at a higher level of awareness was strikingly correlated with her condition. Somehow she could motivate the absence of cancer, but just as easily she could return to it. (I think of this as being like a violin string whose pitch varies as you slide your finger up and down it.) The word that comes to mind when a scientist thinks of such sudden changes is quantum.
The wood
denotes a discrete jump from one level of functioning
to a higher level
the quantum leap.

Quantum is also a technical term, once known only to physicists hut now growing in popular usage. Formally a quantum is the indivisible
unit
in ‘waves may be emitted or absorbed,” the definition given by, the eminent British physicist stephen Hawking. In layman’s terms, the quantum is a building block. Light is built up from photons, electricity from the charge of one electron, gravity from the graviton ‘ (a hypothetical quantum, not yet found in nature), and so on for all forms of energy each of them is based on a quantum and cannot be broken down into anything smaller.

Both definitions the discrete jump to a higher level and the irreducible level of a force appear to apply to certain cases like Chitra’s. Therefore, I would like to introduce the term quantum healing to describe what happened to her. Although the term is new, the process itself is not. There have always been patients who do not follow the normal course of healing. A tiny minority, for example, do not waste away from cancer; others have tumors that grow much more slowly than what the statistics for their diseases predict. Many cures that share mysterious origins with healing, spontaneous remissions, and the effective use of placebos, or “dummy drugs’” also point toward a quantum leap. Why?
Because in all of these instances, the faculty of inner awareness seems to have promoted a drastic jump–a quantum leap in the healing mechanism.

Consciousness is a force that most of us ‘undervalue. Generally we do not focus our inner awareness or use its real power, even in the most difficult moments of crisis. 1bat may account for why “miracle” cures are greeted with a mixture of awe, disbelief, and reverence, Yet, everyone: consciousness, Perhaps these miracles are extensions’ of normal abilities. When your body mends a broken bone, why is that not a miracle? As a healing process, it is certainly complex, far too complex for medicine to duplicate; it involves an incredible number of perfectly synchronized processes, of which medicine knows only the ,major ones and those imperfectly’

The reason why curing cancer by yourself is a miracle but mending a broken arm is not comes down to the mind-body connection: The broken bone seems to mend itself physically, without the intervention of your mind; yet, a spontaneous cure of cancer so it is widely believed depends on a, special quality of mind, some deep will to live, a heroically positive outlook, or some other rare capacity. This implies that there are two kinds of healing, one that is normal, the other abnormal, or at least exceptional.

I believe that this distinction is false. The broken arm mends because consciousness makes it mend, and the same holds true for the miraculous cancer cure, the long-term survival of AIDS, the healing by faith, and even the ability to live to a great old age without falling prey to disease. The reason why not everyone. manages to take the healing process as far as it can go is that we differ drastically in our ability to mobilize it.

We can see this in the way that different people react ‘to disease. A minute fraction, far less than 1 percent, of all the patients who contract an incurable disease manage to cure themselves. A larger fraction, but still under 5 percent, live much longer than average this is confirmed. in the 2 percent of AIDS patients who have survived longer than eight years, while the vast majority do not survive beyond two. These findings are not. restricted to incurable diseases. Studies have generally shown that only 20 percent of patients with serious but treatable disorders recover with excellent results. That leaves nearly 80 percent who either do not recover or only partially recover. Why is unsuccessful healing so far out of proportion? What marks ‘a survivor as opposed to a non-survivor?

Apparently the successful patients have learned to motivate their own healing, and the most successful have gone much further than that. They have found the secret of quantum healing. They are the geniuses of the mind-body connection. Modem medicine. cannot even begin to duplicate their cures, because no cure that relies on drugs or surgery is so precisely timed, so beautifully coordinated, so benign and free of side effects, so effortless as theirs. Their ability springs from a level so deep that you cannot go any deeper. If we knew what their brains were doing to motivate their bodies, we would have the basic unit of the healing process in our hands.

As yet, medicine has not taken the quantum leap, and the word quantum has no clinical application. Because quantum. physics works with ultrahigh- speed accelerators, you may think that quantum healing uses radioisotopes or X rays. But that is the opposite of what it means. Quantum healing moves away from external, high-technology methods toward the deepest core of the mind-body system. This core is where healing begins. To go there and learn to promote the healing response, you must get past all the grosser levels of the body cells, tissues, organs, and systems -and arrive at the junction point between mind and matter, the point where consciousness actually starts to have an effect.

The quantum itself what it is, ,how it behaves takes up the first half of this article. The second half then blends .he quantum into Ayurveda, making a marriage of two cultures while trying to arrive at one answer. The scientific worldview of the West surprisingly supports
the vision of the ancient sages of India. This is a journey that breaks down barriers and ignores cultural fences. To me, the whole story has to be found out. Chitra asked me for it, and so I am writing for her and all patients like her. Until they find an answer, their lives still hang in the balance.

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Your Guide To More Aggressive Beauty Treatments

October 20, 2009 Uncategorized

Evaluating Your Options And Choosing What’s Best For You.

As a part time English professor who lives in a house on several woodland acres in Massachusetts, complete with two ponds and expansive Rower beds, Randy sounds like she shouldn’t have a care in the world. She has a loving partner, two dogs, and a passion for gardening. a form of outdoor exercise that keeps her in touch with the earth and its they then. Her face speaks another story, belying het current lifestyle and making her look older than she really is. That’s because most of the damage to her skin was done decades previously and is just now coming to fruition, a kind of unfortunate payback for time spent burning the candle at both ends. Her birthday age is fifty-nine, but her Skin Age is sixty-five. She exemplifies what’s possible on a beauty budget between $500 and $3,000 or more.

In her first appointment with me, I told her that smoking. sun, stress, and sleep deprivation were all major factors in her health, and so are reflected in her skin. She was very open with me about the fact she had smoked for thirty years, before stopping in 2000. “I taught at a school in Massachusetts for eight years mat was so understaffed, we had to work almost round the dock to keep it going.” she shared. “What kept me going was coffee, cigarettes, and five hours and forty minutes of sleep per night:’ She knew this figure exactly because her schedule wouldn’t let her sleep any longer. Add to that the sun exposure she received from years spent swimming outdoors and the years of gardening, and one can easily explain the lines and wrinkles, the crow’s feet, the sagging skin, and the broken capillaries on her nose and cheeks. “My skin is a fairly accurate index of some of my activities;’ she says. “I was a smoker and a drinker and a person who spent, and still does spend, considerable time outside, all of which don’t always register well on one’s face. And though I wouldn’t call this a high-stress time in my life, like anyone I’ve experienced relationship breakups, deaths, losses, and disappoint ments- all of those personal stressors that, if one is lucky enough to have a good long life, one undergoes:’ Plus, she hasn’t had the luxury of a natural peaches-and cream complexion to hide behind.”Lovely skin doesn’t run in my family-it’s not one of our generic strong points,” she admits.

So, when Randy walked into my office one day in 2007, she was a virtual canvas of things to fix. After interviewing and examining her, I had plenty of good news: Randy didn’t have any suspicious growths or signs of skin cancer, and she seemed to have put all of her unhealthy, beauty-busting habits behind her. Randy gets eight hours of sleep every night and uses sunscreen every day, though I reminded her to apply it to the back of her neck, an area that’s vulnerable when gardening. I could sense that she had a good handle on the stress in her life, too- you get better at managing it with experience. It’s the stress she has accumulated up to now that has taken a physical toll.

I started with my usual question, asking what she would like to change about her face, or what bothered her in particular. She gave me carte blanche, declaring, “You’re the doctor!” Using a mirror in front of her face, I encouraged her to share what she didn’t like when she looked in the mirror, and a few
specifics came spilling out. “I don’t like these marionette lines,” referring to the creases from her mouth to chin, “and the fact that I don’t have that youthful wide-eyed look anymore, maybe because the skin on my eyelids droops, making one eye kind of squinty. And there are lots of fine wrinkles on my face, which don’t show up in dim light but in good light look all creased, like badly ironed fabric;’ Randy said.

To help soften the crow’s feet under her eyes, the horizontal worry lines on her forehead, and the vertical scowl lines between her brows, we decided to try Botox. This purified form of a muscle-paralyzing substance helps stop the expressive movements that etch in lines and crevices in the first place. Batox can also be used to lift the face in certain places by relaxing the underlying muscles that pull the skin down, which is how I made further improvements. I injected a little Botox into the depressor muscles that drew down the corners of her mouth; to even out her eyelids and make her face symmetrical, I injected Botox in certain spots above her eyebrows. Everyone’s face is asymmetric, with more muscle movement on one side than the other, and so I adjusted the dose of Borax accordingly, to sculpt and correct while performing the injections.

A different substance was needed to smooth out the lines and folds that ran from her nose to the mouth, and from her mouth to the chin. To bring these creases up to the level of the skin, I injected a filler called Perlane, which contains hyaluronic acid, a natural component of skin that thins as we age. And though Randy was a cosmetic-surgery virgin, she didn’t flinch at the needle as it plumped up the lines on her face. Of course it helped that Randy’s skin was prepped beforehand with a topical anesthetic, a 30 percent lidocaine cream that I have especially compounded for my patients at a pharmacy. (Compare that to a ready-made tube of what most doctors use, Emla, which contains only 4 percent lidocaine.)

To even out Randy’s skin tone and refresh its texture, I painted on a mild 20 percent salicylic acid peel, which removed the top layer of dull, poreclogging dead skin cells. After three minutes of ring ling, the acid self neutralized, and Randy’s face was aglow. To cool things off she was given some ice packs as she left, pressing them to her face as she sat on the train home to Massachusetts. Was she self conscious? “Not at all she says, laughing. “There are a lot stranger sights on a train in New York, let me tell you:’ About two weeks later, after the slight bruising from the Perlane shots had faded and the flakiness from the peel had cleared, revealing fresh new skin, Randy began the at-home regimen I had prescribed: a twice-weekly applicarion of Renova (tretinoin cream .02 percent) to help treat surface fine lines, wrinkles. and brown spots.

Two months later, in September, Randy returned for a follow, up visit. This time I addressed the redness on Randy’s cheeks and nose, wielding a pulse-dye laser called the V-Beam to erase the squiggly little red blood vessels called
Randy donned a pair of goggles, held a squishy stress ball in each hand, and listened to me explain what would happen-a sound, a flash, and a pinprick of hear with each zap of the laser. I talked to Randy through the entire procedure, which only took a few minutes.

After the laser work, I took a good long look at Randy’s face and decided to inject a little more Perlane in her nose to-mouth lines and a little morc Botax in her crow’s feet. Such tweakings and touch-ups are an essential part of the dermatologist’s art, as it’s safer to undertreat a new patient than over treat. A few weeks later, after the lasered areas on Randy’s face had healed, she was a new woman with a new and improved visage, one that jibed with her inner sense of self “Even as I’ve aged, I’ve always felt young, but lately I’d been looking in the mirror and thinking, ‘Oh, my god, is that me!’ And now, I look and I think, ‘Oh hi! That’s me! I look good! I look friendly.’” And while she’s happy that the wrinkles are softer and the redness is diminished, she is most pleased that the squinchiness around her eyes is gone. “That’s delighted me the most, that my eyes look more symmetrical:’ The effects are manifold: Because she feels good about the way she looks, she says, she chooses her clothes more carefully. and pays more attention to her hair. “I suddenly want to do everything I can to give myself a good outward appearance:’

Randy’s partner also thinks she looks wonderful, as do her fellow professors and her students. They have been privy to the transformation, as Randy isn’t shy about having had some work done, and has been open from the start to questions from the curious. In fact, she has found herself in the unlikely position of being an authority on cosmetic dermatology, at least in the leafy confines of her college campus. ”A woman I work with wants to know everything,” Randy says, laughing. “She checks out my face up close every day, watching as the lines disappear. And a retired art history professor came up to me and pointed to his marionette lines, saying, ‘I just want to get rid of these; how do I do that!’”


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